JP2022534420A5 - - Google Patents

Info

Publication number
JP2022534420A5
JP2022534420A5 JP2021570895A JP2021570895A JP2022534420A5 JP 2022534420 A5 JP2022534420 A5 JP 2022534420A5 JP 2021570895 A JP2021570895 A JP 2021570895A JP 2021570895 A JP2021570895 A JP 2021570895A JP 2022534420 A5 JP2022534420 A5 JP 2022534420A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
alkyl
hydrogen
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021570895A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022534420A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/035592 external-priority patent/WO2020243720A1/en
Publication of JP2022534420A publication Critical patent/JP2022534420A/ja
Publication of JP2022534420A5 publication Critical patent/JP2022534420A5/ja
Pending legal-status Critical Current

Links

JP2021570895A 2019-05-31 2020-06-01 眼のタンパク質凝集疾患を治療するための薬剤 Pending JP2022534420A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962855560P 2019-05-31 2019-05-31
US62/855,560 2019-05-31
PCT/US2020/035592 WO2020243720A1 (en) 2019-05-31 2020-06-01 Pharmacological agents for treating protein aggregation diseases of the eye

Publications (2)

Publication Number Publication Date
JP2022534420A JP2022534420A (ja) 2022-07-29
JP2022534420A5 true JP2022534420A5 (enExample) 2023-06-09

Family

ID=73553335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021570895A Pending JP2022534420A (ja) 2019-05-31 2020-06-01 眼のタンパク質凝集疾患を治療するための薬剤

Country Status (8)

Country Link
US (1) US20220241247A1 (enExample)
EP (1) EP3976017A4 (enExample)
JP (1) JP2022534420A (enExample)
CN (1) CN114173771A (enExample)
BR (1) BR112021024151A2 (enExample)
CA (1) CA3141998A1 (enExample)
MX (1) MX2021014682A (enExample)
WO (1) WO2020243720A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023512116A (ja) * 2020-01-28 2023-03-23 プロテゴ バイオファーマ, インコーポレイテッド トランスサイレチンの安定化及びトランスサイレチンの誤った折り畳みの阻害のための化合物、組成物、及び方法
CN116963727A (zh) * 2020-11-13 2023-10-27 普莱克斯医药公司 用于治疗眼部病症的药剂
WO2023278604A1 (en) * 2021-06-29 2023-01-05 Plex Pharmaceuticals, Inc. Pharmacological agents for treating ophthalmic diseases
WO2023009585A2 (en) * 2021-07-28 2023-02-02 Protego Biopharma, Inc. Transthyretin stabilizing compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005112913A1 (en) * 2004-05-20 2005-12-01 The Scripps Research Institute Transthyretin stabilization
WO2011116123A1 (en) * 2010-03-19 2011-09-22 Irm Llc Tafamidis for the treatment of ophthalmic diseases
WO2013038351A1 (en) * 2011-09-16 2013-03-21 Pfizer Inc. Solid forms of a transthyretin dissociation inhibitor
JP6068484B2 (ja) * 2011-10-24 2017-01-25 ソム、イノベーション、バイオテック、ソシエダッド、リミターダSom Innovation Biotech, S.L. トランスサイレチン関連アミロイドーシスの新規療法
US9499527B2 (en) * 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of familial amyloid polyneuropathy
US9169214B2 (en) * 2012-12-21 2015-10-27 The Board Of Trustees Of The Leland Stanford Junior University Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
JP2016514091A (ja) * 2013-02-08 2016-05-19 ミスフォールディング ダイアグノスティクス, インコーポレイテッド トランスサイレチン抗体およびその使用
BR112015021836A2 (pt) * 2013-03-08 2017-07-18 Allergan Inc conjugados de antibióticos diretamente ligados com drogas esteroides
US9789091B2 (en) * 2013-03-14 2017-10-17 University Of Massachusetts Methods of inhibiting cataracts and presbyopia
US11872236B2 (en) * 2018-04-05 2024-01-16 Calasia Pharmaceuticals, Inc. Pharmacological agents for treating ocular diseases

Similar Documents

Publication Publication Date Title
JP2021063088A5 (enExample)
CN116249683A8 (zh) 氘甲基取代吡嗪并吡嗪并喹啉酮类衍生物、其制备方法及其在医药上的应用
RU2011103741A (ru) Композиции и способы лечения заболевания сетчатки
RU2005135016A (ru) Производные хинолина в качестве ингибиторов фосфодиэстеразы
JP2022000482A5 (enExample)
JP2023546565A5 (enExample)
JP2017502073A5 (enExample)
JP2008509187A5 (enExample)
JPH08510479A (ja) 眼の炎症障害を処置するための3‐ベンゾイルフェニル酢酸誘導体を含む局所的に投与可能な組成物
JP2006515838A5 (enExample)
JPH06100446A (ja) (S)−α−フルオロメチル−ヒスチジン及びそのエステルを使用するぜん息の治療方法
EA200900827A1 (ru) Фармацевтический состав, содержащий антагонист нейрокининов
CN111295202A (zh) 治疗甲癣的外用制剂
JP2019515040A5 (enExample)
JP2024541569A5 (enExample)
JP2002525318A (ja) 眼、耳および鼻治療用の抗生物質組成物
WO2010075315A2 (en) Topical formulations of flap inhibitors for administration to an eye
EP2983788A1 (en) The local treatment of inflammatory ophthalmic diseases
RU99121654A (ru) Средства для предотвращения или лечения болезней, связанных с чрезмерной пролиферацией эпителиальных пигментных клеток сетчатки
JP2005508341A5 (enExample)
JP5955774B2 (ja) プロスタグランジンアゴニストのプロドラッグの安定した水性組成物およびその使用方法
RU2008108175A (ru) Комбинация соединений, которые можно использовать при лечении респираторных заболеваний, особенно хронической оструктивной болезни легких (copo) и астмы
JP5746224B2 (ja) ミラミスチンを含有する薬剤
JP2021512898A5 (enExample)
JP2018519252A5 (enExample)