JP2022533671A5 - - Google Patents
Info
- Publication number
- JP2022533671A5 JP2022533671A5 JP2021568852A JP2021568852A JP2022533671A5 JP 2022533671 A5 JP2022533671 A5 JP 2022533671A5 JP 2021568852 A JP2021568852 A JP 2021568852A JP 2021568852 A JP2021568852 A JP 2021568852A JP 2022533671 A5 JP2022533671 A5 JP 2022533671A5
- Authority
- JP
- Japan
- Prior art keywords
- complex according
- cell surface
- peptide
- linker
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962851443P | 2019-05-22 | 2019-05-22 | |
| US62/851,443 | 2019-05-22 | ||
| PCT/US2020/034050 WO2020237078A1 (en) | 2019-05-22 | 2020-05-21 | Drug conjugates and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022533671A JP2022533671A (ja) | 2022-07-25 |
| JP2022533671A5 true JP2022533671A5 (https=) | 2023-05-26 |
Family
ID=73458657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568852A Pending JP2022533671A (ja) | 2019-05-22 | 2020-05-21 | 薬物複合体およびその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220211861A1 (https=) |
| EP (1) | EP3972647A4 (https=) |
| JP (1) | JP2022533671A (https=) |
| KR (1) | KR20220012278A (https=) |
| CN (1) | CN113891731A (https=) |
| AU (1) | AU2020277470A1 (https=) |
| CA (1) | CA3138933A1 (https=) |
| SG (1) | SG11202112129SA (https=) |
| WO (1) | WO2020237078A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020357806A1 (en) * | 2019-09-30 | 2022-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Knottin-immunostimulant conjugates and related compositions and methods |
| JP2024532362A (ja) * | 2021-08-27 | 2024-09-05 | イエール ユニバーシティ | 細胞外タンパク質の分子分解誘導剤 |
| WO2023028590A1 (en) | 2021-08-27 | 2023-03-02 | Yale University | Molecular degraders of extracellular proteins |
| CA3247329A1 (en) * | 2022-02-02 | 2023-08-10 | Cancer Targeted Technology Llc | PHOSPHORAMIDATE-BASED SMALL MOLECULE DRUG CONJUGATES TARGETING PSMA |
| WO2024012524A1 (zh) * | 2022-07-14 | 2024-01-18 | 苏州宜联生物医药有限公司 | 抗体药物偶联物及其制备方法和用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1958957A1 (en) * | 2007-02-16 | 2008-08-20 | NascaCell Technologies AG | Polypeptide comprising a knottin protein moiety |
| US10844106B2 (en) * | 2010-11-08 | 2020-11-24 | The Board Of Trustees Of The Leland Stanford Junior University | Fusion proteins comprising an engineered knottin peptide and uses thereof |
| KR101972446B1 (ko) * | 2011-05-27 | 2019-04-25 | 글락소 그룹 리미티드 | Ｂｃｍａ（ｃｄ２６９／ｔｎｆｒｓｆ１７）결합 단백질 |
| UA112434C2 (uk) * | 2011-05-27 | 2016-09-12 | Ґлаксо Ґруп Лімітед | Антигензв'язувальний білок, який специфічно зв'язується з всма |
| US9587001B2 (en) * | 2012-10-19 | 2017-03-07 | The Board Of Trustees Of The Leland Stanford Junior University | Conjugated knottin mini-proteins containing non-natural amino acids |
| CA2957717C (en) * | 2014-08-12 | 2021-10-19 | Massachusetts Institute Of Technology | Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein |
| WO2016102679A1 (en) * | 2014-12-23 | 2016-06-30 | Nbe-Therapeutics Ag | Binding protein drug conjugates comprising anthracycline derivatives |
| WO2016165762A1 (en) * | 2015-04-15 | 2016-10-20 | Ganymed Pharmaceuticals Ag | Drug conjugates comprising antibodies against claudin 18.2 |
| CA2987636A1 (en) * | 2015-06-26 | 2016-12-29 | Fred Hutchinson Cancer Research Center | Therapeutic peptides and methods of use thereof |
| US10888603B2 (en) * | 2016-02-12 | 2021-01-12 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of treating cancer cells expressing tumor-associated integrins |
| US10765625B2 (en) * | 2016-03-15 | 2020-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | Knottin-drug conjugates and methods of using the same |
| US20190292243A1 (en) * | 2016-08-22 | 2019-09-26 | Fred Hutchinson Cancer Research Center | Peptides and methods of use thereof |
| AU2018207303A1 (en) * | 2017-01-10 | 2019-07-25 | xCella Biosciences, Inc. | Combination tumor treatment with an integrin-binding-Fc fusion protein and immune modulator |
| AU2018289581C1 (en) * | 2017-06-23 | 2025-01-30 | VelosBio Inc. | ROR1 antibody immunoconjugates |
| AU2020357806A1 (en) * | 2019-09-30 | 2022-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Knottin-immunostimulant conjugates and related compositions and methods |
| WO2022026906A2 (en) * | 2020-07-30 | 2022-02-03 | The Board Of Trustees Of The Leland Stanford Junior University | Lysosomal targeting molecules comprising knottin peptides and related compositions and methods |
-
2020
- 2020-05-21 JP JP2021568852A patent/JP2022533671A/ja active Pending
- 2020-05-21 AU AU2020277470A patent/AU2020277470A1/en active Pending
- 2020-05-21 WO PCT/US2020/034050 patent/WO2020237078A1/en not_active Ceased
- 2020-05-21 CN CN202080037432.3A patent/CN113891731A/zh active Pending
- 2020-05-21 KR KR1020217041069A patent/KR20220012278A/ko active Pending
- 2020-05-21 EP EP20809958.0A patent/EP3972647A4/en active Pending
- 2020-05-21 SG SG11202112129SA patent/SG11202112129SA/en unknown
- 2020-05-21 CA CA3138933A patent/CA3138933A1/en active Pending
- 2020-05-21 US US17/609,284 patent/US20220211861A1/en active Pending
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