CA3138933A1 - Drug conjugates and methods of using same - Google Patents

Drug conjugates and methods of using same Download PDF

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Publication number
CA3138933A1
CA3138933A1 CA3138933A CA3138933A CA3138933A1 CA 3138933 A1 CA3138933 A1 CA 3138933A1 CA 3138933 A CA3138933 A CA 3138933A CA 3138933 A CA3138933 A CA 3138933A CA 3138933 A1 CA3138933 A1 CA 3138933A1
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CA
Canada
Prior art keywords
conjugate
fragment
peptide
drug
heavy chain
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Pending
Application number
CA3138933A
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English (en)
French (fr)
Inventor
Jennifer R. Cochran
Caitlyn MILLER
James R. KINTZING
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Leland Stanford Junior University
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Leland Stanford Junior University
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Publication date
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Publication of CA3138933A1 publication Critical patent/CA3138933A1/en
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    • A—HUMAN NECESSITIES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
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CA3247329A1 (en) * 2022-02-02 2023-08-10 Cancer Targeted Technology Llc PHOSPHORAMIDATE-BASED SMALL MOLECULE DRUG CONJUGATES TARGETING PSMA
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