JP2022530028A5 - - Google Patents
Info
- Publication number
- JP2022530028A5 JP2022530028A5 JP2021562948A JP2021562948A JP2022530028A5 JP 2022530028 A5 JP2022530028 A5 JP 2022530028A5 JP 2021562948 A JP2021562948 A JP 2021562948A JP 2021562948 A JP2021562948 A JP 2021562948A JP 2022530028 A5 JP2022530028 A5 JP 2022530028A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- fumarate
- compound
- temperature
- fumaric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962837858P | 2019-04-24 | 2019-04-24 | |
| US62/837,858 | 2019-04-24 | ||
| PCT/CA2020/050535 WO2020215155A1 (en) | 2019-04-24 | 2020-04-23 | Crystal form s4 of the plk4 inhibitor (lr,2s)-(e)-2-(3-(4-((cis-2,6-dimethylmorpholino)methyl)styryl)- 1 h-imidazol-6- yl)-5'-methoxyspiro[cyclopropane-l,3'-indolin]-2'-one fumarate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022530028A JP2022530028A (ja) | 2022-06-27 |
| JP2022530028A5 true JP2022530028A5 (enExample) | 2023-04-25 |
| JP7705351B2 JP7705351B2 (ja) | 2025-07-09 |
Family
ID=72940551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021562948A Active JP7705351B2 (ja) | 2019-04-24 | 2020-04-23 | ＰＬＫ４阻害剤である（１Ｒ，２Ｓ）－（Ｅ）－２－（３－（４－（（ｃｉｓ－２，６－ジメチルモルホリノ）メチル）スチリル）－１Ｈ－イミダゾール－６－イル）－５’－メトキシスピロ［シクロプロパン－１，３’－インドリン］－２’－オンフマル酸塩のＳ４結晶形 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12325700B2 (enExample) |
| EP (1) | EP3959209A4 (enExample) |
| JP (1) | JP7705351B2 (enExample) |
| KR (1) | KR20220004102A (enExample) |
| CN (1) | CN113966330B (enExample) |
| BR (1) | BR112021021106A2 (enExample) |
| CA (1) | CA3137191A1 (enExample) |
| EA (1) | EA202192903A1 (enExample) |
| IL (1) | IL287394A (enExample) |
| MA (1) | MA55767A (enExample) |
| MX (1) | MX2021012993A (enExample) |
| SA (1) | SA521430647B1 (enExample) |
| SG (1) | SG11202111003UA (enExample) |
| TW (1) | TWI862582B (enExample) |
| WO (1) | WO2020215155A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023013225A (es) | 2021-05-11 | 2024-01-15 | Oric Pharmaceuticals Inc | Inhibidores de la cinasa 4 similar a polo. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7205328B2 (en) | 2002-10-21 | 2007-04-17 | Irm Llc | Oxindoles with anti-HIV activity |
| DE102005005395A1 (de) | 2005-02-03 | 2006-08-10 | Schering Aktiengesellschaft | Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
| GB0606234D0 (en) | 2006-03-29 | 2006-05-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutically acceptable salts and polymorphic forms |
| US20110201818A1 (en) | 2007-09-25 | 2011-08-18 | Takeda Pharmaceutical Company Limited | Polo-like kinase inhibitors |
| JP2011506494A (ja) | 2007-12-21 | 2011-03-03 | ユニバーシティ・ヘルス・ネットワーク | 癌の治療に有用なキナーゼ阻害剤としてのインダゾリル、ベンズイミダゾリル、ベンゾトリアゾリル置換インドルモン誘導体 |
| EP2417127B1 (en) | 2009-04-06 | 2014-02-26 | University Health Network | Kinase inhibitors and method of treating cancer with same |
| ES2660146T3 (es) | 2009-04-29 | 2018-03-21 | Nerviano Medical Sciences S.R.L. | Sales del inhibidor de cdk |
| PT2556071T (pt) | 2010-04-06 | 2016-11-22 | Univ Health Network | Inibidores de quinase e seus usos no tratamento de cancro |
| WO2012000103A1 (en) | 2010-07-02 | 2012-01-05 | University Health Network | Methods of targeting pten mutant diseases and compositions therefor |
| WO2012048411A1 (en) | 2010-10-13 | 2012-04-19 | University Health Network | Plk-4 inhibitors and method of treating cancer with same |
| KR20130105675A (ko) | 2010-11-25 | 2013-09-25 | 라티오팜 게엠베하 | 아파티닙의 신규 염 및 다형 |
| US9580390B2 (en) | 2011-10-12 | 2017-02-28 | University Health Network | Indazole compounds as kinase inhibitors and method of treating cancer with same |
| ES2908200T3 (es) | 2013-10-18 | 2022-04-28 | Univ Health Network | Tratamiento para el cáncer de páncreas |
| HRP20190564T1 (hr) | 2013-10-18 | 2019-05-17 | University Health Network | Sol i kristalni oblici inhibitora plk-4 |
-
2020
- 2020-04-23 EP EP20795605.3A patent/EP3959209A4/en active Pending
- 2020-04-23 JP JP2021562948A patent/JP7705351B2/ja active Active
- 2020-04-23 CN CN202080030678.8A patent/CN113966330B/zh active Active
- 2020-04-23 MA MA055767A patent/MA55767A/fr unknown
- 2020-04-23 MX MX2021012993A patent/MX2021012993A/es unknown
- 2020-04-23 BR BR112021021106A patent/BR112021021106A2/pt unknown
- 2020-04-23 TW TW109113591A patent/TWI862582B/zh active
- 2020-04-23 US US17/605,108 patent/US12325700B2/en active Active
- 2020-04-23 EA EA202192903A patent/EA202192903A1/ru unknown
- 2020-04-23 KR KR1020217037777A patent/KR20220004102A/ko not_active Ceased
- 2020-04-23 SG SG11202111003UA patent/SG11202111003UA/en unknown
- 2020-04-23 CA CA3137191A patent/CA3137191A1/en active Pending
- 2020-04-23 WO PCT/CA2020/050535 patent/WO2020215155A1/en not_active Ceased
-
2021
- 2021-10-19 IL IL287394A patent/IL287394A/en unknown
- 2021-10-20 SA SA521430647A patent/SA521430647B1/ar unknown
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