JP2022529016A5 - - Google Patents

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Publication number
JP2022529016A5
JP2022529016A5 JP2021561677A JP2021561677A JP2022529016A5 JP 2022529016 A5 JP2022529016 A5 JP 2022529016A5 JP 2021561677 A JP2021561677 A JP 2021561677A JP 2021561677 A JP2021561677 A JP 2021561677A JP 2022529016 A5 JP2022529016 A5 JP 2022529016A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
composition according
egfr
tki
Prior art date
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Granted
Application number
JP2021561677A
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English (en)
Japanese (ja)
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JP2022529016A (ja
JP7822597B2 (ja
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Priority claimed from PCT/US2020/028547 external-priority patent/WO2020214831A1/en
Publication of JP2022529016A publication Critical patent/JP2022529016A/ja
Publication of JP2022529016A5 publication Critical patent/JP2022529016A5/ja
Application granted granted Critical
Publication of JP7822597B2 publication Critical patent/JP7822597B2/ja
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JP2021561677A 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがん細胞に対する抗腫瘍活性を有する化合物 Active JP7822597B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962835354P 2019-04-17 2019-04-17
US62/835,354 2019-04-17
PCT/US2020/028547 WO2020214831A1 (en) 2019-04-17 2020-04-16 Compounds with anti-tumor activity against cancer cells bearing tyrosine kinase inhibitor resistant egfr mutations

Publications (3)

Publication Number Publication Date
JP2022529016A JP2022529016A (ja) 2022-06-16
JP2022529016A5 true JP2022529016A5 (https=) 2023-04-24
JP7822597B2 JP7822597B2 (ja) 2026-03-03

Family

ID=72837840

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021561677A Active JP7822597B2 (ja) 2019-04-17 2020-04-16 チロシンキナーゼ阻害剤耐性egfr変異を有するがん細胞に対する抗腫瘍活性を有する化合物

Country Status (7)

Country Link
US (1) US20220193074A1 (https=)
EP (1) EP3955928A4 (https=)
JP (1) JP7822597B2 (https=)
KR (1) KR20220003546A (https=)
CN (1) CN113784718A (https=)
CA (1) CA3132816A1 (https=)
WO (1) WO2020214831A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021016149A2 (pt) 2019-02-26 2021-10-13 Janssen Biotech, Inc. Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
US11879013B2 (en) 2019-05-14 2024-01-23 Janssen Biotech, Inc. Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
JP7783182B2 (ja) 2020-02-12 2025-12-09 ヤンセン バイオテツク,インコーポレーテツド c-METエクソン14スキッピング変異を有する患者の治療
MX2024008057A (es) 2021-12-30 2024-08-28 Biomea Fusion Inc Compuestos de pirazina como inhibidores de flt3.
WO2024097994A1 (en) * 2022-11-03 2024-05-10 Board Of Regents, The University Of Texas System Methods for the detection and treatment of non-small-cell lung cancer
CN115998743B (zh) * 2023-01-16 2024-05-28 威尚(上海)生物医药有限公司 喹唑啉类化合物在克服奥希替尼耐药中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017136709A (ru) * 2015-04-23 2019-05-23 Медиммьюн Лимитед Комбинированное лечение немелкоклеточного рака легкого с выявленной мутацией в egfr
KR102771603B1 (ko) * 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
EP3585389A4 (en) * 2017-02-22 2020-12-23 G1 Therapeutics, Inc. EGFR-CAUSED CANCER TREATMENT WITH LESS SIDE EFFECTS

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