JP2022527788A5 - - Google Patents

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Publication number
JP2022527788A5
JP2022527788A5 JP2021557927A JP2021557927A JP2022527788A5 JP 2022527788 A5 JP2022527788 A5 JP 2022527788A5 JP 2021557927 A JP2021557927 A JP 2021557927A JP 2021557927 A JP2021557927 A JP 2021557927A JP 2022527788 A5 JP2022527788 A5 JP 2022527788A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
composition according
exon
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021557927A
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English (en)
Japanese (ja)
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JP2022527788A (ja
JP7650814B2 (ja
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Priority claimed from PCT/US2020/025228 external-priority patent/WO2020205521A1/en
Publication of JP2022527788A publication Critical patent/JP2022527788A/ja
Publication of JP2022527788A5 publication Critical patent/JP2022527788A5/ja
Priority to JP2025038928A priority Critical patent/JP2025090740A/ja
Application granted granted Critical
Publication of JP7650814B2 publication Critical patent/JP7650814B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021557927A 2019-03-29 2020-03-27 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物 Active JP7650814B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025038928A JP2025090740A (ja) 2019-03-29 2025-03-12 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826843P 2019-03-29 2019-03-29
US62/826,843 2019-03-29
PCT/US2020/025228 WO2020205521A1 (en) 2019-03-29 2020-03-27 Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025038928A Division JP2025090740A (ja) 2019-03-29 2025-03-12 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Publications (3)

Publication Number Publication Date
JP2022527788A JP2022527788A (ja) 2022-06-06
JP2022527788A5 true JP2022527788A5 (https=) 2023-04-04
JP7650814B2 JP7650814B2 (ja) 2025-03-25

Family

ID=72666976

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021557927A Active JP7650814B2 (ja) 2019-03-29 2020-03-27 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物
JP2025038928A Pending JP2025090740A (ja) 2019-03-29 2025-03-12 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025038928A Pending JP2025090740A (ja) 2019-03-29 2025-03-12 Egfrまたはher2エクソン20挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Country Status (13)

Country Link
US (2) US20220143023A1 (https=)
EP (1) EP3946293A4 (https=)
JP (2) JP7650814B2 (https=)
KR (1) KR20210149103A (https=)
CN (1) CN113939284A (https=)
AU (1) AU2020254499A1 (https=)
BR (1) BR112021019489A2 (https=)
CA (1) CA3131864A1 (https=)
IL (1) IL286742A (https=)
MX (1) MX2021011948A (https=)
PH (1) PH12021552395A1 (https=)
SG (1) SG11202110669WA (https=)
WO (1) WO2020205521A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110129434A (zh) * 2018-02-08 2019-08-16 埃提斯生物技术(上海)有限公司 胆汁中生物标志物在诊断恶性肿瘤中的应用
BR112021016149A2 (pt) 2019-02-26 2021-10-13 Janssen Biotech, Inc. Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.
EP3956035A4 (en) * 2019-04-17 2023-01-25 Board of Regents, The University of Texas System ANTI-CANCER LINKS WITH TYROSINE KINASE RESISTANT EGFR MUTATIONS
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
US11879013B2 (en) 2019-05-14 2024-01-23 Janssen Biotech, Inc. Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
JP7783182B2 (ja) 2020-02-12 2025-12-09 ヤンセン バイオテツク,インコーポレーテツド c-METエクソン14スキッピング変異を有する患者の治療
PY21113397A (es) * 2020-12-29 2022-10-12 Spectrum Pharmaceuticals Inc Tratamiento para tumores sólidos malignos
WO2022206929A1 (zh) * 2021-04-01 2022-10-06 上海医药集团股份有限公司 一种化合物在制备靶向ErbB2突变体的抑制药物中的应用
WO2023015149A1 (en) * 2021-08-02 2023-02-09 Spectrum Pharmaceuticals, Inc. Treatment of non-small cell lung cancer with poziotinib
KR20230063731A (ko) 2021-11-02 2023-05-09 주식회사 엘지에너지솔루션 전해액의 분할 주입을 포함하는 이차전지의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10308658B2 (en) * 2015-10-19 2019-06-04 Sunshine Lake Pharma Co., Ltd. Salt of EGFR inhibitor, crystalline form and uses thereof
KR102771603B1 (ko) * 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
EP3687542A1 (en) * 2017-09-27 2020-08-05 AI Therapeutics, Inc. Therapeutic methods relating to hsp90 inhibitors
WO2019178239A1 (en) * 2018-03-13 2019-09-19 Board Of Regents, The University Of Texas System Methods for treatment of cancers with egfr activating mutations
AU2019243738B2 (en) * 2018-03-27 2024-05-30 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing HER2 exon 19 mutations
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.

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