KR20210149103A - Egfr 또는 her2 엑손 20 삽입을 지니는 암 세포에 대한 항종양 활성을 갖는 화합물 - Google Patents

Egfr 또는 her2 엑손 20 삽입을 지니는 암 세포에 대한 항종양 활성을 갖는 화합물 Download PDF

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KR20210149103A
KR20210149103A KR1020217035240A KR20217035240A KR20210149103A KR 20210149103 A KR20210149103 A KR 20210149103A KR 1020217035240 A KR1020217035240 A KR 1020217035240A KR 20217035240 A KR20217035240 A KR 20217035240A KR 20210149103 A KR20210149103 A KR 20210149103A
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cancer
exon
mutations
egfr
her2
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재클린 로비쇼
모니크 닐슨
존 브이. 헤이마치
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더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
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KR1020217035240A 2019-03-29 2020-03-27 Egfr 또는 her2 엑손 20 삽입을 지니는 암 세포에 대한 항종양 활성을 갖는 화합물 Pending KR20210149103A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826843P 2019-03-29 2019-03-29
US62/826,843 2019-03-29
PCT/US2020/025228 WO2020205521A1 (en) 2019-03-29 2020-03-27 Compounds with anti-tumor activity against cancer cells bearing egfr or her2 exon 20 insertions

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Publication Number Publication Date
KR20210149103A true KR20210149103A (ko) 2021-12-08

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KR1020217035240A Pending KR20210149103A (ko) 2019-03-29 2020-03-27 Egfr 또는 her2 엑손 20 삽입을 지니는 암 세포에 대한 항종양 활성을 갖는 화합물

Country Status (13)

Country Link
US (2) US20220143023A1 (https=)
EP (1) EP3946293A4 (https=)
JP (2) JP7650814B2 (https=)
KR (1) KR20210149103A (https=)
CN (1) CN113939284A (https=)
AU (1) AU2020254499A1 (https=)
BR (1) BR112021019489A2 (https=)
CA (1) CA3131864A1 (https=)
IL (1) IL286742A (https=)
MX (1) MX2021011948A (https=)
PH (1) PH12021552395A1 (https=)
SG (1) SG11202110669WA (https=)
WO (1) WO2020205521A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023080475A1 (ko) 2021-11-02 2023-05-11 주식회사 엘지에너지솔루션 전해액의 분할 주입을 포함하는 이차전지의 제조방법

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CN110129434A (zh) * 2018-02-08 2019-08-16 埃提斯生物技术（上海）有限公司 胆汁中生物标志物在诊断恶性肿瘤中的应用
BR112021016149A2 (pt) 2019-02-26 2021-10-13 Janssen Biotech, Inc. Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.
EP3956035A4 (en) * 2019-04-17 2023-01-25 Board of Regents, The University of Texas System ANTI-CANCER LINKS WITH TYROSINE KINASE RESISTANT EGFR MUTATIONS
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
US11879013B2 (en) 2019-05-14 2024-01-23 Janssen Biotech, Inc. Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
JP7783182B2 (ja) 2020-02-12 2025-12-09 ヤンセン バイオテツク，インコーポレーテツド ｃ－ＭＥＴエクソン１４スキッピング変異を有する患者の治療
PY21113397A (es) * 2020-12-29 2022-10-12 Spectrum Pharmaceuticals Inc Tratamiento para tumores sólidos malignos
WO2022206929A1 (zh) * 2021-04-01 2022-10-06 上海医药集团股份有限公司 一种化合物在制备靶向ErbB2突变体的抑制药物中的应用
WO2023015149A1 (en) * 2021-08-02 2023-02-09 Spectrum Pharmaceuticals, Inc. Treatment of non-small cell lung cancer with poziotinib

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US10308658B2 (en) * 2015-10-19 2019-06-04 Sunshine Lake Pharma Co., Ltd. Salt of EGFR inhibitor, crystalline form and uses thereof
KR102771603B1 (ko) * 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
EP3687542A1 (en) * 2017-09-27 2020-08-05 AI Therapeutics, Inc. Therapeutic methods relating to hsp90 inhibitors
WO2019178239A1 (en) * 2018-03-13 2019-09-19 Board Of Regents, The University Of Texas System Methods for treatment of cancers with egfr activating mutations
AU2019243738B2 (en) * 2018-03-27 2024-05-30 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing HER2 exon 19 mutations
MX2021011948A (es) * 2019-03-29 2022-01-04 Univ Texas Compuestos con actividad antitumoral contra células cancerígenas que llevan inserciones de exon 20 effr o her2.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023080475A1 (ko) 2021-11-02 2023-05-11 주식회사 엘지에너지솔루션 전해액의 분할 주입을 포함하는 이차전지의 제조방법

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Publication number Publication date
JP2022527788A (ja) 2022-06-06
JP7650814B2 (ja) 2025-03-25
US20220143023A1 (en) 2022-05-12
US20250312348A1 (en) 2025-10-09
EP3946293A4 (en) 2023-05-03
MX2021011948A (es) 2022-01-04
EP3946293A1 (en) 2022-02-09
SG11202110669WA (en) 2021-10-28
CN113939284A (zh) 2022-01-14
JP2025090740A (ja) 2025-06-17
BR112021019489A2 (pt) 2022-02-08
CA3131864A1 (en) 2020-10-08
IL286742A (en) 2021-10-31
WO2020205521A1 (en) 2020-10-08
PH12021552395A1 (en) 2022-06-13
AU2020254499A1 (en) 2021-10-28

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