JP2022527499A5 - - Google Patents

Info

Publication number
JP2022527499A5
JP2022527499A5 JP2021557941A JP2021557941A JP2022527499A5 JP 2022527499 A5 JP2022527499 A5 JP 2022527499A5 JP 2021557941 A JP2021557941 A JP 2021557941A JP 2021557941 A JP2021557941 A JP 2021557941A JP 2022527499 A5 JP2022527499 A5 JP 2022527499A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutical product
mutations
product according
poziotinib
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021557941A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022527499A (ja
JP7700043B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/025478 external-priority patent/WO2020205632A1/en
Publication of JP2022527499A publication Critical patent/JP2022527499A/ja
Publication of JP2022527499A5 publication Critical patent/JP2022527499A5/ja
Application granted granted Critical
Publication of JP7700043B2 publication Critical patent/JP7700043B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021557941A 2019-03-29 2020-03-27 Her2エクソン21挿入を有するがん細胞に対する抗腫瘍活性を有する化合物 Active JP7700043B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826758P 2019-03-29 2019-03-29
US62/826,758 2019-03-29
PCT/US2020/025478 WO2020205632A1 (en) 2019-03-29 2020-03-27 Compounds with anti-tumor activity against cancer cells bearing her2 exon 21 insertions

Publications (3)

Publication Number Publication Date
JP2022527499A JP2022527499A (ja) 2022-06-02
JP2022527499A5 true JP2022527499A5 (https=) 2023-03-30
JP7700043B2 JP7700043B2 (ja) 2025-06-30

Family

ID=72666271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557941A Active JP7700043B2 (ja) 2019-03-29 2020-03-27 Her2エクソン21挿入を有するがん細胞に対する抗腫瘍活性を有する化合物

Country Status (13)

Country Link
US (1) US20220175778A1 (https=)
EP (1) EP3946632A4 (https=)
JP (1) JP7700043B2 (https=)
KR (1) KR20210145161A (https=)
CN (1) CN113766955A (https=)
AU (1) AU2020256119A1 (https=)
BR (1) BR112021019376A2 (https=)
CA (1) CA3132834A1 (https=)
IL (1) IL286576A (https=)
MX (1) MX2021011925A (https=)
PH (1) PH12021552110A1 (https=)
SG (1) SG11202109531UA (https=)
WO (1) WO2020205632A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3956035A4 (en) * 2019-04-17 2023-01-25 Board of Regents, The University of Texas System ANTI-CANCER LINKS WITH TYROSINE KINASE RESISTANT EGFR MUTATIONS
PY21113397A (es) * 2020-12-29 2022-10-12 Spectrum Pharmaceuticals Inc Tratamiento para tumores sólidos malignos
CA3264494A1 (en) * 2022-08-09 2024-02-15 Heligenics Inc. METHOD FOR EVALUATING THE CLINICAL RELEVANCE OF A GENETIC VARIANCE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101217526B1 (ko) * 2010-06-11 2013-01-02 한미사이언스 주식회사 아마이드 유도체 또는 이의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물
KR101317809B1 (ko) * 2011-06-07 2013-10-16 한미약품 주식회사 암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물
IN2014DN05803A (https=) * 2011-12-14 2015-05-15 Univ Texas
KR20190015360A (ko) * 2016-05-31 2019-02-13 네스텍 소시에테아노님 Her2 및 her3 경로 아형 분류를 기반으로 한, 유방암 환자에 대한 약물 치료법의 선택 방법
KR102771603B1 (ko) * 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
MX2021007554A (es) * 2018-12-21 2021-08-11 Univ Texas Terapia de combinacion para el tratamiento de cancer.
KR102477643B1 (ko) * 2019-05-09 2022-12-13 주식회사 엘지에너지솔루션 전기화학소자용 분리막 및 이를 포함하는 전기화학소자

Similar Documents

Publication Publication Date Title
JP2022529945A5 (https=)
JP2022527788A5 (https=)
JP2022529016A5 (https=)
JP2020502059A5 (https=)
Ponti et al. BRAF, NRAS and C-KIT advanced melanoma: clinico-pathological features, targeted-therapy strategies and survival
JP2022527499A5 (https=)
JP2021517894A5 (https=)
US20190381048A1 (en) Combination therapy involving diaryl macrocyclic compounds
JP2019533670A5 (https=)
JP2019532011A5 (https=)
WO2017129094A1 (zh) 一种egfr/her2受体酪氨酸激酶抑制剂在制备治疗her2突变癌症药物中的用途
JP2021519306A5 (https=)
WO2025179058A1 (en) Pyridopyrimidine derivative as kras g12c inhibitor for the treatment of brain metastasis
JP2022515128A5 (https=)
Malakar et al. The role of BRAF inhibitors in the management of ameloblastoma: a literature review
RU2020134932A (ru) Соединения с противоопухолевой активностью против раковых клеток, несущих мутации в экзоне 19her2
CN110840892A (zh) 酪氨酸激酶抑制剂与cdk4/6抑制剂联合在制备预防或治疗肿瘤疾病的药物中的用途
US20230241081A1 (en) Method for Treating Melanoma
CN113840608B (zh) Cdk4/6抑制剂与vegfr抑制剂联合在制备治疗肿瘤的药物中的用途
JP7334194B2 (ja) Tp53突然変異状態及び高頻度突然変異状態に基づくがん治療法
Grellety et al. A clinical case of invasive lobular breast carcinoma with ERBB2 and CDH1 mutations presenting a dramatic response to anti-HER2-directed therapy
CN115698338A (zh) 用妥卡替尼治疗her2突变型癌症的方法
Yim et al. The genomic landscape and its clinical implications in hepatocellular carcinoma
US20130005747A1 (en) Method for selecting a cancer therapy
Higashi et al. A Case of BRAF-V600E-Positive Pulmonary Pleomorphic Carcinoma Successfully Treated With Dabrafenib and Trametinib Administered via a Percutaneous Endoscopic Gastrojejunostomy Tube for Ileus Caused by Small Intestinal Metastasis