JP2022522803A - 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー - Google Patents

結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー Download PDF

Info

Publication number
JP2022522803A
JP2022522803A JP2021551880A JP2021551880A JP2022522803A JP 2022522803 A JP2022522803 A JP 2022522803A JP 2021551880 A JP2021551880 A JP 2021551880A JP 2021551880 A JP2021551880 A JP 2021551880A JP 2022522803 A JP2022522803 A JP 2022522803A
Authority
JP
Japan
Prior art keywords
cyfra21
flt3l
areg
colorectal cancer
precancerous stage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021551880A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022522803A5 (https=
Inventor
ロドリゲス アナ カルメン マルティン
パラシオス ロサ ペレス
アランス ロシオ アロジョ
Original Assignee
アドバンスド マーカー ディスカバリー エセ． エレ．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アドバンスド マーカー ディスカバリー エセ． エレ． filed Critical アドバンスド マーカー ディスカバリー エセ． エレ．
Publication of JP2022522803A publication Critical patent/JP2022522803A/ja
Publication of JP2022522803A5 publication Critical patent/JP2022522803A5/ja
Priority to JP2024224464A priority Critical patent/JP2025038186A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021551880A 2019-03-01 2020-02-28 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー Pending JP2022522803A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024224464A JP2025038186A (ja) 2019-03-01 2024-12-19 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19382157.6 2019-03-01
EP19382157 2019-03-01
EP19382156 2019-03-01
EP19382156.8 2019-03-01
PCT/EP2020/055277 WO2020178172A1 (en) 2019-03-01 2020-02-28 Protein signature for the diagnosis of colorectal cancer and/or pre-cancerous stage thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024224464A Division JP2025038186A (ja) 2019-03-01 2024-12-19 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー

Publications (2)

Publication Number Publication Date
JP2022522803A true JP2022522803A (ja) 2022-04-20
JP2022522803A5 JP2022522803A5 (https=) 2023-03-07

Family

ID=69631636

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021551880A Pending JP2022522803A (ja) 2019-03-01 2020-02-28 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー
JP2024224464A Pending JP2025038186A (ja) 2019-03-01 2024-12-19 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024224464A Pending JP2025038186A (ja) 2019-03-01 2024-12-19 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー

Country Status (10)

Country Link
US (1) US20220276249A1 (https=)
EP (1) EP3931571B1 (https=)
JP (2) JP2022522803A (https=)
KR (1) KR102769007B1 (https=)
CN (1) CN113785199B (https=)
AU (1) AU2020230963B2 (https=)
CA (1) CA3131729A1 (https=)
ES (1) ES2952139T3 (https=)
MX (1) MX2021010451A (https=)
WO (1) WO2020178172A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2952139T3 (es) * 2019-03-01 2023-10-27 Advanced Marker Discovery S L Firma proteica para el diagnóstico de cáncer colorrectal y/o etapa precancerosa del mismo
WO2021185982A1 (en) * 2020-03-19 2021-09-23 Advanced Marker Discovery S.l. Protein signature for screening general population for colorectal cancer and/or pre-cancerous stage thereof
CA3202255A1 (en) 2020-12-21 2022-06-30 Hayley WARSINSKE Markers for the early detection of colon cell proliferative disorders
KR102900859B1 (ko) * 2021-12-31 2025-12-17 주식회사 이노제닉스 대장암 및 대장 용종 또는 진행 선종의 선별 방법 및 그 응용

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522172A (ja) * 2004-12-23 2008-06-26 エフ．ホフマン−ラ ロシュ アーゲー 直腸結腸癌用マーカーとしてのｃｙｆｒａ２１−１の使用
JP2011506917A (ja) * 2007-12-10 2011-03-03 エフ．ホフマン−ラ ロシュ アーゲー 結腸直腸癌のためのマーカーパネル
US20140220006A1 (en) * 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
JP2015190959A (ja) * 2014-03-28 2015-11-02 学校法人北里研究所 卵巣明細胞腺癌細胞の検出方法、卵巣明細胞腺癌診断薬、卵巣明細胞腺癌診断用プライマー、卵巣明細胞腺癌診断用キット、及び卵巣明細胞腺癌診断用プローブ
JP2016536568A (ja) * 2013-09-18 2016-11-24 アデレード リサーチ アンド イノベイション ピーティーワイ エルティーディーＡｄｅｌａｉｄｅ Ｒｅｓｅａｒｃｈ ＆ Ｉｎｎｏｖａｔｉｏｎ Ｐｔｙ Ｌｔｄ 卵巣がんの自己抗体バイオマーカー
US20180080937A1 (en) * 2015-03-27 2018-03-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Biomarker Panel For Diagnosing Cancer
JP2018136122A (ja) * 2015-05-29 2018-08-30 国立研究開発法人国立がん研究センター 膵がんを診断するための血漿バイオマーカーパネル
WO2019023371A1 (en) * 2017-07-26 2019-01-31 Lambert David E REFLECTIVE ROAD MARKER

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103140760B (zh) * 2010-07-14 2016-01-27 联邦科学与工业研究组织 结肠直肠癌的诊断
US20180160885A1 (en) * 2016-12-13 2018-06-14 Prosper Abitbol Endoscopy based medical devices, methods, and innovations
KR102018205B1 (ko) * 2017-07-24 2019-09-05 (주) 바이오인프라생명과학 대장암 진단용 조성물 및 상기 조성물을 이용한 대장암 진단 방법
ES2952139T3 (es) * 2019-03-01 2023-10-27 Advanced Marker Discovery S L Firma proteica para el diagnóstico de cáncer colorrectal y/o etapa precancerosa del mismo
WO2021185982A1 (en) * 2020-03-19 2021-09-23 Advanced Marker Discovery S.l. Protein signature for screening general population for colorectal cancer and/or pre-cancerous stage thereof

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522172A (ja) * 2004-12-23 2008-06-26 エフ．ホフマン−ラ ロシュ アーゲー 直腸結腸癌用マーカーとしてのｃｙｆｒａ２１−１の使用
JP2011506917A (ja) * 2007-12-10 2011-03-03 エフ．ホフマン−ラ ロシュ アーゲー 結腸直腸癌のためのマーカーパネル
US20140220006A1 (en) * 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
JP2016536568A (ja) * 2013-09-18 2016-11-24 アデレード リサーチ アンド イノベイション ピーティーワイ エルティーディーＡｄｅｌａｉｄｅ Ｒｅｓｅａｒｃｈ ＆ Ｉｎｎｏｖａｔｉｏｎ Ｐｔｙ Ｌｔｄ 卵巣がんの自己抗体バイオマーカー
JP2015190959A (ja) * 2014-03-28 2015-11-02 学校法人北里研究所 卵巣明細胞腺癌細胞の検出方法、卵巣明細胞腺癌診断薬、卵巣明細胞腺癌診断用プライマー、卵巣明細胞腺癌診断用キット、及び卵巣明細胞腺癌診断用プローブ
US20180080937A1 (en) * 2015-03-27 2018-03-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Biomarker Panel For Diagnosing Cancer
JP2018136122A (ja) * 2015-05-29 2018-08-30 国立研究開発法人国立がん研究センター 膵がんを診断するための血漿バイオマーカーパネル
WO2019023371A1 (en) * 2017-07-26 2019-01-31 Lambert David E REFLECTIVE ROAD MARKER

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
HONGDA CHEN: "Development and validation of a panel of five proteins as blood biomarkers for early detection of co", CLINICAL EPIDEMIOLOGY, vol. 9, JPN6023053043, 2017, pages 517 - 526, ISSN: 0005395251 *
HONGDA CHEN: "Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer", JOURNAL OF CLINICAL EPIDEMIOLOGY, vol. 75, JPN6023053041, 2016, pages 108 - 114, ISSN: 0005395249 *
HONGDA CHEN: "Head-to-head comparison and Evaluation of 92 Plasma Protein Biomarkers for Early Detection of Colore", CLINICAL CANCER RESEARCH, vol. 21, no. 4, JPN6023053040, July 2015 (2015-07-01), pages 3318 - 3326, ISSN: 0005395248 *
JING QIAN: "Biomarker discovery study of inflammatory proteins for colorectal cancer early detection demonstrate", JOURNAL OF CLINICAL EPIDEMIOLOGY, vol. 104, JPN6023053045, 1 August 2018 (2018-08-01), pages 24 - 34, ISSN: 0005232607 *
LIM DO HYOUNG: "Feasibility of CYFRA 21-1 as a serum biomarker for the detection of colorectal adenoma and advanced", JOURNAL OF CLINICAL LABORATORY ANALYSIS, vol. 32, no. 1, JPN6023053046, 2018, pages 22163, ISSN: 0005395250 *
宮下知治: "大腸癌における血清CEA・CA19-9・CYFRA21-1・IAP測定によるcombination assayの臨床的意義", 日本大腸肛門病会誌, vol. 53, JPN6023053036, 2000, pages 76 - 82, ISSN: 0005395247 *

Also Published As

Publication number Publication date
US20220276249A1 (en) 2022-09-01
AU2020230963A1 (en) 2021-09-30
CN113785199A (zh) 2021-12-10
EP3931571B1 (en) 2023-06-07
BR112021017248A2 (pt) 2021-11-09
EP3931571C0 (en) 2023-06-07
KR102769007B1 (ko) 2025-02-14
ES2952139T3 (es) 2023-10-27
CA3131729A1 (en) 2020-09-10
JP2025038186A (ja) 2025-03-18
WO2020178172A1 (en) 2020-09-10
EP3931571A1 (en) 2022-01-05
KR20210134946A (ko) 2021-11-11
AU2020230963B2 (en) 2026-03-12
MX2021010451A (es) 2021-12-10
CN113785199B (zh) 2024-02-09

Similar Documents

Publication Publication Date Title
Rho et al. Protein and glycomic plasma markers for early detection of adenoma and colon cancer
US11193935B2 (en) Compositions, methods and kits for diagnosis of lung cancer
JP2025038186A (ja) 結腸直腸癌及び／又はその前癌段階の診断用タンパク質シグネチャー
US11193934B2 (en) Sample hepatocarcinoma classification with YKL-40 to MASP2 concentration ratio
Lucas et al. Validation of a serum-based biomarker signature for detection of early-stage pancreatic ductal adenocarcinoma
US20170168058A1 (en) Compositions, methods and kits for diagnosis of lung cancer
CN118465282A (zh) 预测结直肠癌肝转移的生物标志物组合、试剂盒、系统及其应用
TWI522367B (zh) Urine biomarkers are used to predict bladder and kidney cancer
WO2021185982A1 (en) Protein signature for screening general population for colorectal cancer and/or pre-cancerous stage thereof
RU2830580C2 (ru) Белковая сигнатура для диагностики колоректального рака или его предраковой стадии
WO2024004523A1 (ja) 大腸がんバイオマーカーおよびその用途
Dimitrov et al. The high elevation of c-reactive protein levels at admission represents an early mortality predictor in patients with complicated intra-abdominal infections
BR112021017248B1 (pt) Método in vitro para o diagnóstico de câncer colorretal e/ou um seu estágio pré- canceroso, usos in vitro da combinação de [flt3l e cyfra21-1] e da combinação de da combinação de [flt3l e cyfra21-1 e areg], ou [flt3l e cyfra21-1 e areg e erbb4], ou {flt3l e cyfra21-1 e areg e clec2c] em uma amostra biológica obtida do paciente,e uso de um kit de partes
JP7660077B2 (ja) 診断方法
Budnik et al. Landscaping of Urine Proteome: Unlocking Diagnostic Potential and Overcoming Unique Challenges
CN120369969A (zh) 一种用于区分肺癌和肺炎的生物标志物及其应用
CN120405156A (zh) 一种用于肺癌分型的血清蛋白生物标志物及其应用
CN115505641A (zh) 生物标志物在制备胰腺癌源性新发糖尿病预测和/或预后评估的试剂盒中的应用
US20160060708A1 (en) Method for detecting the risk of early gastric cancer
HK1227103A1 (en) Compositions, methods and kits for diagnosis of lung cancer

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20210922

RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20210922

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230227

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230227

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20231222

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240109

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20240409

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240607

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240820