CN113785199B - 用于诊断结肠直肠癌和/或其癌前阶段的蛋白质特征 - Google Patents

用于诊断结肠直肠癌和/或其癌前阶段的蛋白质特征 Download PDF

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CN113785199B
CN113785199B CN202080032932.8A CN202080032932A CN113785199B CN 113785199 B CN113785199 B CN 113785199B CN 202080032932 A CN202080032932 A CN 202080032932A CN 113785199 B CN113785199 B CN 113785199B
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areg
cyfra21
flt3l
colorectal cancer
combination
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CN113785199A (zh
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安娜·卡门·马丁·罗德里古兹
罗莎·佩雷斯·帕拉西奥斯
罗西奥·阿罗约·阿兰兹
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Advanced Marker Discovery SL AMADIX
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Advanced Marker Discovery SL AMADIX
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202080032932.8A 2019-03-01 2020-02-28 用于诊断结肠直肠癌和/或其癌前阶段的蛋白质特征 Active CN113785199B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19382157.6 2019-03-01
EP19382157 2019-03-01
EP19382156 2019-03-01
EP19382156.8 2019-03-01
PCT/EP2020/055277 WO2020178172A1 (en) 2019-03-01 2020-02-28 Protein signature for the diagnosis of colorectal cancer and/or pre-cancerous stage thereof

Publications (2)

Publication Number Publication Date
CN113785199A CN113785199A (zh) 2021-12-10
CN113785199B true CN113785199B (zh) 2024-02-09

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US (1) US20220276249A1 (https=)
EP (1) EP3931571B1 (https=)
JP (2) JP2022522803A (https=)
KR (1) KR102769007B1 (https=)
CN (1) CN113785199B (https=)
AU (1) AU2020230963B2 (https=)
CA (1) CA3131729A1 (https=)
ES (1) ES2952139T3 (https=)
MX (1) MX2021010451A (https=)
WO (1) WO2020178172A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2952139T3 (es) * 2019-03-01 2023-10-27 Advanced Marker Discovery S L Firma proteica para el diagnóstico de cáncer colorrectal y/o etapa precancerosa del mismo
WO2021185982A1 (en) * 2020-03-19 2021-09-23 Advanced Marker Discovery S.l. Protein signature for screening general population for colorectal cancer and/or pre-cancerous stage thereof
CA3202255A1 (en) 2020-12-21 2022-06-30 Hayley WARSINSKE Markers for the early detection of colon cell proliferative disorders
KR102900859B1 (ko) * 2021-12-31 2025-12-17 주식회사 이노제닉스 대장암 및 대장 용종 또는 진행 선종의 선별 방법 및 그 응용

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105755112A (zh) * 2010-07-14 2016-07-13 联邦科学与工业研究组织 结肠直肠癌的诊断
WO2019022371A1 (ko) * 2017-07-24 2019-01-31 (주) 바이오인프라생명과학 대장암 진단용 조성물 및 상기 조성물을 이용한 대장암 진단 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005014386D1 (de) * 2004-12-23 2009-06-18 Roche Diagnostics Gmbh Verwendung von cyfra 21-1 und osteopontin als marker für kolorektalkarzinome
CN101896817A (zh) * 2007-12-10 2010-11-24 霍夫曼-拉罗奇有限公司 用于结直肠癌的标记物组
US20140220006A1 (en) * 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
US20160291025A1 (en) * 2013-09-18 2016-10-06 Adelaide Research & Innovation Pty Ltd Autoantibody biomarkers of ovarian cancer
JP6339399B2 (ja) * 2014-03-28 2018-06-06 学校法人北里研究所 卵巣明細胞腺癌細胞の検出方法、卵巣明細胞腺癌診断薬、卵巣明細胞腺癌診断用プライマー、卵巣明細胞腺癌診断用キット、及び卵巣明細胞腺癌診断用プローブ
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
JP2018136122A (ja) * 2015-05-29 2018-08-30 国立研究開発法人国立がん研究センター 膵がんを診断するための血漿バイオマーカーパネル
US20180160885A1 (en) * 2016-12-13 2018-06-14 Prosper Abitbol Endoscopy based medical devices, methods, and innovations
US10968583B2 (en) * 2017-07-26 2021-04-06 David E. Lambert Reflective road marker
ES2952139T3 (es) * 2019-03-01 2023-10-27 Advanced Marker Discovery S L Firma proteica para el diagnóstico de cáncer colorrectal y/o etapa precancerosa del mismo
WO2021185982A1 (en) * 2020-03-19 2021-09-23 Advanced Marker Discovery S.l. Protein signature for screening general population for colorectal cancer and/or pre-cancerous stage thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105755112A (zh) * 2010-07-14 2016-07-13 联邦科学与工业研究组织 结肠直肠癌的诊断
WO2019022371A1 (ko) * 2017-07-24 2019-01-31 (주) 바이오인프라생명과학 대장암 진단용 조성물 및 상기 조성물을 이용한 대장암 진단 방법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer;Hongda Chen等;《Clinical Epidemiology》;第第9卷卷;517-526页 *

Also Published As

Publication number Publication date
US20220276249A1 (en) 2022-09-01
AU2020230963A1 (en) 2021-09-30
CN113785199A (zh) 2021-12-10
EP3931571B1 (en) 2023-06-07
JP2022522803A (ja) 2022-04-20
BR112021017248A2 (pt) 2021-11-09
EP3931571C0 (en) 2023-06-07
KR102769007B1 (ko) 2025-02-14
ES2952139T3 (es) 2023-10-27
CA3131729A1 (en) 2020-09-10
JP2025038186A (ja) 2025-03-18
WO2020178172A1 (en) 2020-09-10
EP3931571A1 (en) 2022-01-05
KR20210134946A (ko) 2021-11-11
AU2020230963B2 (en) 2026-03-12
MX2021010451A (es) 2021-12-10

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