JP2022521233A - 桂皮酸を含む組成物及びその使用方法 - Google Patents

桂皮酸を含む組成物及びその使用方法 Download PDF

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JP2022521233A
JP2022521233A JP2021548664A JP2021548664A JP2022521233A JP 2022521233 A JP2022521233 A JP 2022521233A JP 2021548664 A JP2021548664 A JP 2021548664A JP 2021548664 A JP2021548664 A JP 2021548664A JP 2022521233 A JP2022521233 A JP 2022521233A
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patient
cinnamic acid
pharmaceutical composition
composition
effective amount
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Japanese (ja)
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JP2022521233A5 (https=
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カリパーダ パハン，
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ラッシュ・ユニバーシティ・メディカル・センター
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021548664A 2019-02-25 2020-02-25 桂皮酸を含む組成物及びその使用方法 Withdrawn JP2022521233A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962810055P 2019-02-25 2019-02-25
US62/810,055 2019-02-25
PCT/US2020/019568 WO2020176432A1 (en) 2019-02-25 2020-02-25 Compositions including cinnamic acid and methods of use thereof

Publications (2)

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JP2022521233A true JP2022521233A (ja) 2022-04-06
JP2022521233A5 JP2022521233A5 (https=) 2023-03-07

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JP2021548664A Withdrawn JP2022521233A (ja) 2019-02-25 2020-02-25 桂皮酸を含む組成物及びその使用方法

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US (1) US12478598B2 (https=)
EP (1) EP3930704A4 (https=)
JP (1) JP2022521233A (https=)
KR (1) KR20210130772A (https=)
CN (1) CN113473981A (https=)
AU (1) AU2020229316A1 (https=)
CA (1) CA3130761A1 (https=)
EA (1) EA202192199A1 (https=)
WO (1) WO2020176432A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202002639D0 (en) * 2020-02-25 2020-04-08 Ucl Business Ltd Therapy
CN116390761A (zh) * 2020-10-28 2023-07-04 拉什大学医学中心 肉桂酸苄酯组合物在治疗甘氨酸脑病和尿素循环障碍中的应用
EP4440554A4 (en) * 2021-12-01 2025-10-29 Goldlake Lifesciences Pvt Ltd PHARMACEUTICAL FORMULATION AND ITS PREPARATION PROCESS
CA3241282A1 (en) * 2021-12-16 2023-06-22 Kalipada PAHAN Benzoic acid salts for treatment of nervous system injuries and disorders
WO2024201533A1 (en) * 2023-03-31 2024-10-03 Sava Healthcare Limited A parenteral composition of cinnamic acid

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100479405B1 (ko) * 2002-05-24 2005-03-30 주식회사 싸이제닉 신남산 이합체, 그 제조방법 및 퇴행성 뇌질환 치료를위한 그의 용도
JP6836905B2 (ja) * 2014-01-17 2021-03-03 ラッシュ・ユニバーシティ・メディカル・センター 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用
ES2799309T3 (es) * 2014-09-29 2020-12-16 Cellix Bio Private Ltd Compuestos y composiciones para el tratamiento de esclerosis múltiple
CN107205976A (zh) * 2014-11-19 2017-09-26 拉什大学医学中心 用于治疗溶酶体病症的组合物和方法
US11008277B2 (en) 2016-06-13 2021-05-18 Syneurx International (Taiwan) Corp. Co-crystals of sodium benzoate and uses thereof
EP3691630A4 (en) * 2017-10-06 2021-10-27 Rush University Medical Center USE OF A COMPOSITION CONTAINING BENZOATE TO TREAT GLYCINE ENCEPHALOPATHY
GB202002639D0 (en) 2020-02-25 2020-04-08 Ucl Business Ltd Therapy
CN116390761A (zh) * 2020-10-28 2023-07-04 拉什大学医学中心 肉桂酸苄酯组合物在治疗甘氨酸脑病和尿素循环障碍中的应用
EP4281118A4 (en) * 2021-01-20 2025-01-01 Rush University Medical Center Improved treatment for globoid cell leukodsytrophy or krabbe disease

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Publication number Publication date
EP3930704A1 (en) 2022-01-05
EP3930704A4 (en) 2022-11-16
WO2020176432A1 (en) 2020-09-03
AU2020229316A1 (en) 2021-09-16
US20220133664A1 (en) 2022-05-05
CA3130761A1 (en) 2020-09-03
US12478598B2 (en) 2025-11-25
CN113473981A (zh) 2021-10-01
EA202192199A1 (ru) 2021-12-17
KR20210130772A (ko) 2021-11-01

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