JP2022518504A5 - - Google Patents

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Publication number
JP2022518504A5
JP2022518504A5 JP2021542384A JP2021542384A JP2022518504A5 JP 2022518504 A5 JP2022518504 A5 JP 2022518504A5 JP 2021542384 A JP2021542384 A JP 2021542384A JP 2021542384 A JP2021542384 A JP 2021542384A JP 2022518504 A5 JP2022518504 A5 JP 2022518504A5
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JP
Japan
Application number
JP2021542384A
Other languages
Japanese (ja)
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JP2022518504A (ja
JPWO2020154645A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/015026 external-priority patent/WO2020154645A1/en
Publication of JP2022518504A publication Critical patent/JP2022518504A/ja
Publication of JP2022518504A5 publication Critical patent/JP2022518504A5/ja
Publication of JPWO2020154645A5 publication Critical patent/JPWO2020154645A5/ja
Pending legal-status Critical Current

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JP2021542384A 2019-01-24 2020-01-24 閉端dna(cedna)ならびに遺伝子療法または核酸療法に関連する免疫応答を低減させる方法における使用 Pending JP2022518504A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201962796417P 2019-01-24 2019-01-24
US201962796450P 2019-01-24 2019-01-24
US62/796,417 2019-01-24
US62/796,450 2019-01-24
US201962800303P 2019-02-01 2019-02-01
US201962800285P 2019-02-01 2019-02-01
US62/800,285 2019-02-01
US62/800,303 2019-02-01
US201962814414P 2019-03-06 2019-03-06
US201962814424P 2019-03-06 2019-03-06
US62/814,414 2019-03-06
US62/814,424 2019-03-06
US201962857542P 2019-06-05 2019-06-05
US62/857,542 2019-06-05
PCT/US2020/015026 WO2020154645A1 (en) 2019-01-24 2020-01-24 Close-ended dna (cedna) and use in methods of reducing gene or nucleic acid therapy related immune response

Publications (3)

Publication Number Publication Date
JP2022518504A JP2022518504A (ja) 2022-03-15
JP2022518504A5 true JP2022518504A5 (https=) 2023-02-02
JPWO2020154645A5 JPWO2020154645A5 (https=) 2023-02-02

Family

ID=71735812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021542384A Pending JP2022518504A (ja) 2019-01-24 2020-01-24 閉端dna(cedna)ならびに遺伝子療法または核酸療法に関連する免疫応答を低減させる方法における使用

Country Status (11)

Country Link
US (1) US20220119840A1 (https=)
EP (1) EP3914717A4 (https=)
JP (1) JP2022518504A (https=)
KR (1) KR20210119416A (https=)
CN (1) CN113412331A (https=)
AU (1) AU2020211457A1 (https=)
CA (1) CA3127799A1 (https=)
MA (1) MA54826A (https=)
MX (1) MX2021008874A (https=)
SG (1) SG11202107922QA (https=)
WO (1) WO2020154645A1 (https=)

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Publication number Priority date Publication date Assignee Title
TW202545984A (zh) 2017-08-09 2025-12-01 美商生物化學醫療公司 核酸分子及其用途
SG11202005271TA (en) * 2018-01-19 2020-07-29 Generation Bio Co Closed-ended dna vectors obtainable from cell-free synthesis and process for obtaining cedna vectors
CN108920903B (zh) * 2018-07-09 2022-04-01 湘潭大学 基于朴素贝叶斯的LncRNA与疾病的关联关系预测方法及系统
WO2020033863A1 (en) 2018-08-09 2020-02-13 Bioverativ Therapeutics Inc. Nucleic acid molecules and uses thereof for non-viral gene therapy
EP3956448A4 (en) * 2019-04-18 2022-10-19 University of Massachusetts AIM2 INHIBITORS AND USES THEREOF
US20210371465A1 (en) * 2020-03-26 2021-12-02 Yale University Method of using a tlr9 antagonist as an anti-inflammatory and anti-fibrotic agent
CN116234917A (zh) 2020-07-27 2023-06-06 安杰瑞姆生物科学公司 Dna分子组合物及其制备方法和使用方法
US20220090130A1 (en) * 2020-08-23 2022-03-24 Bioverativ Therapeutics Inc. MODIFIED BACULOVIRUS SYSTEM FOR IMPROVED PRODUCTION OF CLOSED-ENDED DNA (ceDNA)
CN112138164B (zh) * 2020-09-25 2022-06-03 徐州医科大学 Aim2在制备降低car-t治疗毒副作用的药物中的应用
EP4297728A1 (en) 2021-02-23 2024-01-03 Poseida Therapeutics, Inc. Compositions and methods for delivery of nucleic acids
CA3230386A1 (en) * 2021-07-23 2023-01-26 Spark Therapeutics, Inc. Methods and composition for non-viral dna delivery
AU2022211795A1 (en) * 2021-08-06 2023-02-23 Syte.Bio Inc. Hairpin loop ended self-complementary double-stranded covalently closed linear dna vector, manufacturing system and process, and uses of said resulting dna vector
JP2024532476A (ja) * 2021-09-02 2024-09-05 モレキュラー アクシオム エルエルシー Nlrp3またはnlrp1発現を調節するための組成物及び方法
CN114796216A (zh) * 2022-01-04 2022-07-29 南京医科大学 甲氟喹在防治全身代谢性炎症疾病中的应用
JP2025532680A (ja) * 2022-09-20 2025-10-01 ザ・カウンシル・オヴ・ザ・クイーンズランド・インスティテュート・オヴ・メディカル・リサーチ 抗線維化マイクロrna組成物
EP4630561A1 (en) 2022-12-09 2025-10-15 Takeda Pharmaceutical Company Limited Modified immunomodulators
AU2024224841A1 (en) 2023-02-21 2025-08-21 Poseida Therapeutics, Inc. Aav piggybac transposon polynucleotide compositions and methods of use therefor
CN121532216A (zh) * 2023-04-18 2026-02-13 赛仁生物技术公司 腺相关病毒载体组合物和使用方法
WO2025064507A1 (en) 2023-09-19 2025-03-27 Poseida Therapeutics, Inc. Compositions and methods for integration of viral vectors
WO2025114932A1 (en) * 2023-11-30 2025-06-05 Sanofi Purification of closed-ended dna molecules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8377898B2 (en) * 2006-10-12 2013-02-19 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
EP2500434A1 (en) * 2011-03-12 2012-09-19 Association Institut de Myologie Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
US20140242093A1 (en) * 2011-07-29 2014-08-28 Fred Hutchinson Cancer Research Center Methods and compositions for modulating the innate immune response and/or myogenesis in a mammalian subject
ES2977259T3 (es) * 2014-11-05 2024-08-21 Cartesian Therapeutics Inc Métodos y composiciones relacionadas con nanovehículos sintéticos con rapamicina en un estado sobresaturado estable
WO2017152149A1 (en) * 2016-03-03 2017-09-08 University Of Massachusetts Closed-ended linear duplex dna for non-viral gene transfer
US11339396B2 (en) * 2016-06-08 2022-05-24 President And Fellows Of Harvard College Engineered viral vector reduces induction of inflammatory and immune responses

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