|
RU2019130504A
(ru)
|
2017-02-28 |
2021-03-30 |
Вор Байофарма, Инк. |
Композиции и способы ингибирования линиеспецифических белков
|
|
CA3110837A1
(en)
|
2018-08-28 |
2020-03-05 |
Vor Biopharma Inc. |
Genetically engineered hematopoietic stem cells and uses thereof
|
|
WO2020051562A2
(en)
|
2018-09-07 |
2020-03-12 |
Beam Therapeutics Inc. |
Compositions and methods for improving base editing
|
|
WO2020160517A1
(en)
*
|
2019-01-31 |
2020-08-06 |
Beam Therapeutics Inc. |
Nucleobase editors having reduced off-target deamination and methods of using same to modify a nucleobase target sequence
|
|
CN120174005A
(zh)
|
2019-02-13 |
2025-06-20 |
比姆医疗股份有限公司 |
具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
|
|
EP3773918A4
(en)
|
2019-03-05 |
2022-01-05 |
Nkarta, Inc. |
CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
|
|
CN114981409A
(zh)
*
|
2019-09-03 |
2022-08-30 |
美洛德生物医药公司 |
用于基因组整合的方法和组合物
|
|
EP4034138A4
(en)
|
2019-09-27 |
2024-07-31 |
Beam Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
|
|
US20240238344A1
(en)
*
|
2020-08-28 |
2024-07-18 |
Vor Biopharma Inc. |
Compositions and methods for cd123 modification
|
|
WO2022056459A1
(en)
*
|
2020-09-14 |
2022-03-17 |
Vor Biopharma, Inc. |
Compositions and methods for cd5 modification
|
|
WO2022061115A1
(en)
*
|
2020-09-18 |
2022-03-24 |
Vor Biopharma Inc. |
Compositions and methods for cd7 modification
|
|
CN116322716A
(zh)
*
|
2020-09-23 |
2023-06-23 |
克里斯珀医疗股份公司 |
Regnase-1和/或TGFBRII被破坏的基因工程化T细胞具有改善的功能性和持久性
|
|
CA3196831A1
(en)
*
|
2020-09-25 |
2022-03-31 |
Beam Therapeutics Inc. |
Fratricide resistant modified immune cells and methods of using the same
|
|
WO2022072643A1
(en)
*
|
2020-09-30 |
2022-04-07 |
Vor Biopharma Inc. |
Compositions and methods for cd30 gene modification
|
|
CN116801890A
(zh)
*
|
2020-11-04 |
2023-09-22 |
小利兰·斯坦福大学董事会 |
用于增强治疗性免疫细胞功效的方法和组合物
|
|
US11459372B2
(en)
|
2020-11-30 |
2022-10-04 |
Crispr Therapeutics Ag |
Gene-edited natural killer cells
|
|
EP4255453A4
(en)
*
|
2020-12-03 |
2025-03-26 |
Nkarta, Inc. |
Methods for manipulating immune cells for increased potency and persistence, as well as uses of engineered cells in immunotherapy
|
|
IL303506A
(en)
*
|
2020-12-11 |
2023-08-01 |
Intellia Therapeutics Inc |
Polynucleotides, compositions, and methods for genome editing involving deamination
|
|
WO2022144632A1
(en)
|
2020-12-30 |
2022-07-07 |
Crispr Therapeutics Ag |
Compositions and methods for differentiating stem cells into nk cells
|
|
CA3204417A1
(en)
*
|
2021-01-29 |
2022-08-04 |
Allogene Therapeutics, Inc. |
Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products
|
|
WO2022215978A1
(ko)
*
|
2021-04-05 |
2022-10-13 |
주식회사 셀렌진 |
Pdcd-1 유전자에 상보적인 가이드 rna 및 이의 용도
|
|
CN113179160B
(zh)
*
|
2021-04-15 |
2022-03-18 |
中国电子科技集团公司第三十研究所 |
一种适用于qkd中私钥放大的最优输入码长处理方法及单元
|
|
WO2022235971A2
(en)
*
|
2021-05-06 |
2022-11-10 |
Systems Oncology, Llc |
Compositions for inhibiting growth of targeted cells
|
|
BR112023023642A2
(pt)
*
|
2021-05-11 |
2024-01-30 |
Myeloid Therapeutics Inc |
Métodos e composições para integração genômica
|
|
AU2022331424A1
(en)
*
|
2021-08-16 |
2024-02-22 |
Beam Therapeutics Inc. |
Persistent allogeneic modified immune cells and methods of use thereof
|
|
AU2022335499A1
(en)
|
2021-08-27 |
2024-02-22 |
Metagenomi Therapeutics, Inc. |
Enzymes with ruvc domains
|
|
JP2024532382A
(ja)
*
|
2021-08-30 |
2024-09-05 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
アデノシンデアミナーゼの細胞表面発現を有するt細胞及びその使用
|
|
JP2024537991A
(ja)
|
2021-10-14 |
2024-10-18 |
アーセナル バイオサイエンシズ インコーポレイテッド |
共発現されるshRNAと論理ゲートシステムとを有する免疫細胞
|
|
CN113980896B
(zh)
*
|
2021-10-27 |
2023-10-20 |
中国人民解放军军事科学院军事医学研究院 |
Irf1在调控间充质干细胞免疫调节作用及产品上的应用
|
|
JP2024540723A
(ja)
*
|
2021-11-03 |
2024-11-01 |
インテリア セラピューティクス,インコーポレーテッド |
免疫療法のためのcd38組成物及び方法
|
|
EP4430195A4
(en)
*
|
2021-11-12 |
2025-09-24 |
Georgia Tech Res Inst |
ADENOSINE DEAMINASE 1 COMPOSITIONS AND METHODS OF USE THEREOF
|
|
AU2022396533A1
(en)
|
2021-11-24 |
2024-05-02 |
Metagenomi Therapeutics, Inc. |
Endonuclease systems
|
|
WO2023114777A2
(en)
*
|
2021-12-14 |
2023-06-22 |
The Trustees Of The University Of Pennsylvania |
Cd5 modified cells comprising chimeric antigen receptors (cars) for treatment of solid tumors
|
|
CN114774364B
(zh)
*
|
2022-04-26 |
2024-04-26 |
深圳市体内生物医药科技有限公司 |
一种嵌合抗原受体t细胞及其制备方法和应用
|
|
EP4532697A2
(en)
*
|
2022-06-03 |
2025-04-09 |
Beam Therapeutics Inc. |
Modified regulatory t cells and methods of using the same
|
|
KR20250057777A
(ko)
|
2022-07-25 |
2025-04-29 |
인테리우스 바이오테라퓨틱스, 인코포레이티드 |
돌연변이된 폴리펩티드, 이를 포함하는 조성물, 및 그 용도(mutated polypeptides, compositions comprising the same, and uses thereof)
|
|
JP2025529590A
(ja)
*
|
2022-09-08 |
2025-09-04 |
エイゾスバイオ、インコーポレイテッド |
細胞内トランスフェクションのための新規なポリペプチド組成物
|
|
EP4587570A2
(en)
*
|
2022-09-16 |
2025-07-23 |
Arsenal Biosciences, Inc. |
Immune cells with combination gene perturbations
|
|
WO2024064642A2
(en)
*
|
2022-09-19 |
2024-03-28 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for modulating t cell function
|
|
KR20250084940A
(ko)
*
|
2022-09-30 |
2025-06-11 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
입양 t 세포 치료를 향상시키기 위한 조성물 및 방법
|
|
IL322949A
(en)
|
2023-03-03 |
2025-10-01 |
Arsenal Biosciences Inc |
Systems targeting PSMA and CA9
|
|
WO2024186841A2
(en)
*
|
2023-03-06 |
2024-09-12 |
La Jolla Institute For Immunology |
Nfkbid cells and methods for immunotherapy
|
|
CN121358848A
(zh)
*
|
2023-03-21 |
2026-01-16 |
苏州沙砾生物科技有限公司 |
一种修饰的细胞及其用途
|
|
EP4694917A1
(en)
*
|
2023-04-12 |
2026-02-18 |
Beam Therapeutics Inc. |
Modified immune effector cells with improved efficacy
|
|
EP4455157A1
(en)
*
|
2023-04-27 |
2024-10-30 |
Fundacion Publica Andaluza Progreso Y Salud M.P.- Fps |
Polynuceotide for t cell specific transgene expression
|
|
AU2024274412A1
(en)
*
|
2023-05-16 |
2025-12-11 |
Prime Medicine, Inc. |
Genome editing compositions targeting the b2m gene and methods of use
|
|
KR20260018068A
(ko)
*
|
2023-05-26 |
2026-02-06 |
에디타스 메디신, 인코포레이티드 |
Cd70 발현을 표적화하는 crispr 관련 방법 및 조성물
|
|
CN116590237B
(zh)
*
|
2023-05-29 |
2023-10-31 |
上海贝斯昂科生物科技有限公司 |
一种遗传修饰的自然杀伤细胞及其制备和用途
|
|
WO2025111533A1
(en)
*
|
2023-11-22 |
2025-05-30 |
The General Hospital Corporation |
Car-t cells comprising a cdkn1b gene knockout and methods of use thereof
|
|
WO2025119306A1
(zh)
*
|
2023-12-06 |
2025-06-12 |
北京齐禾生科生物科技有限公司 |
优化工程化t细胞的碱基编辑系统及其应用
|
|
WO2025122896A1
(en)
*
|
2023-12-08 |
2025-06-12 |
The Trustees Of The University Of Pennsylvania |
Cd5 modified cells comprising heterologous tcrs and methods of using the same
|
|
WO2025238594A2
(en)
*
|
2024-05-16 |
2025-11-20 |
Fondazione Istituto Italiano Di Tecnologia |
DESIGN OF SYNTHETIC miRNAS TO RESTORE THE CORRECT GENE DOSAGE OF GENES ASSOCIATED WITH T LYMPHOCYTE EXHAUSTION
|