JP2022517101A5 - - Google Patents
Info
- Publication number
- JP2022517101A5 JP2022517101A5 JP2021540415A JP2021540415A JP2022517101A5 JP 2022517101 A5 JP2022517101 A5 JP 2022517101A5 JP 2021540415 A JP2021540415 A JP 2021540415A JP 2021540415 A JP2021540415 A JP 2021540415A JP 2022517101 A5 JP2022517101 A5 JP 2022517101A5
- Authority
- JP
- Japan
- Prior art keywords
- gpr156
- rodent
- gene
- human
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962793523P | 2019-01-17 | 2019-01-17 | |
| US62/793,523 | 2019-01-17 | ||
| US201962899849P | 2019-09-13 | 2019-09-13 | |
| US62/899,849 | 2019-09-13 | ||
| PCT/US2020/013801 WO2020150426A1 (en) | 2019-01-17 | 2020-01-16 | A rodent model of mood disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022517101A JP2022517101A (ja) | 2022-03-04 |
| JP2022517101A5 true JP2022517101A5 (https=) | 2023-01-04 |
| JP7509786B2 JP7509786B2 (ja) | 2024-07-02 |
Family
ID=69529068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021540415A Active JP7509786B2 (ja) | 2019-01-17 | 2020-01-16 | 気分障害の齧歯類モデル |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11470828B2 (https=) |
| EP (1) | EP3911154A1 (https=) |
| JP (1) | JP7509786B2 (https=) |
| KR (1) | KR20210116480A (https=) |
| CN (1) | CN113423266A (https=) |
| AU (1) | AU2020209184A1 (https=) |
| CA (1) | CA3124514A1 (https=) |
| IL (1) | IL284078A (https=) |
| MX (1) | MX2021008291A (https=) |
| SG (1) | SG11202106423PA (https=) |
| WO (1) | WO2020150426A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7509786B2 (ja) * | 2019-01-17 | 2024-07-02 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 気分障害の齧歯類モデル |
| CN116676334B (zh) * | 2023-02-08 | 2025-05-27 | 深圳大学 | 抑郁症动物模型的构建方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001004137A1 (en) | 1999-07-09 | 2001-01-18 | Genaissance Pharmaceuticals, Inc. | Drug target isogenes: polymorphisms in the osteoclastogenesis inhibitory factor gene |
| ATE437948T1 (de) * | 2000-06-20 | 2009-08-15 | Bionomics Ltd | Mutation, welche mit epilepsie assoziiert ist |
| EP1581648A2 (en) | 2002-09-09 | 2005-10-05 | Nura, Inc. | G protein coupled receptors and uses thereof |
| US20040216177A1 (en) | 2003-04-25 | 2004-10-28 | Otsuka Pharmaceutical Co., Ltd. | Congenic rats containing a mutant GPR10 gene |
| ES2463476T3 (es) | 2004-10-19 | 2014-05-28 | Regeneron Pharmaceuticals, Inc. | Método para generar un ratón homocigótico para una modificación genética |
| EP1940876A1 (en) | 2005-10-28 | 2008-07-09 | Takeda Cambridge Limited | Gpr 26 g-protein coupled receptor |
| EP2091556B1 (en) * | 2006-11-15 | 2018-07-25 | Omeros Corporation | Non-human animal comprising a mutation in the sreb2/gpr85 gene as animal model of metabolic disease |
| US8518392B2 (en) | 2009-08-14 | 2013-08-27 | Regeneron Pharmaceuticals, Inc. | Promoter-regulated differentiation-dependent self-deleting cassette |
| EP4502152A3 (en) * | 2009-10-06 | 2025-04-30 | Regeneron Pharmaceuticals, Inc. | Genetically modified mice and engraftment |
| US20160058891A1 (en) | 2011-11-01 | 2016-03-03 | Roche Glycart Ag | In vivo adcc model |
| MX384291B (es) | 2013-02-20 | 2025-03-14 | Regeneron Pharma | Modificación genética de ratas. |
| DK3456831T3 (da) | 2013-04-16 | 2021-09-06 | Regeneron Pharma | Målrettet modifikation af rottegenom |
| DK3422845T3 (da) | 2016-02-29 | 2021-08-30 | Regeneron Pharma | Gnavere med et humaniseret tmprss-gen |
| EP3491014B1 (en) | 2016-07-28 | 2023-04-05 | Regeneron Pharmaceuticals, Inc. | Allele-specific primer or probe hybridized to a nucleic acid molecule encoding a gpr156 variant |
| JP7509786B2 (ja) * | 2019-01-17 | 2024-07-02 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 気分障害の齧歯類モデル |
-
2020
- 2020-01-16 JP JP2021540415A patent/JP7509786B2/ja active Active
- 2020-01-16 WO PCT/US2020/013801 patent/WO2020150426A1/en not_active Ceased
- 2020-01-16 US US16/744,493 patent/US11470828B2/en active Active
- 2020-01-16 AU AU2020209184A patent/AU2020209184A1/en not_active Abandoned
- 2020-01-16 EP EP20704748.1A patent/EP3911154A1/en not_active Withdrawn
- 2020-01-16 MX MX2021008291A patent/MX2021008291A/es unknown
- 2020-01-16 CA CA3124514A patent/CA3124514A1/en active Pending
- 2020-01-16 SG SG11202106423PA patent/SG11202106423PA/en unknown
- 2020-01-16 KR KR1020217022378A patent/KR20210116480A/ko not_active Ceased
- 2020-01-16 CN CN202080007946.4A patent/CN113423266A/zh active Pending
-
2021
- 2021-06-16 IL IL284078A patent/IL284078A/en unknown
-
2022
- 2022-08-10 US US17/818,730 patent/US20230123787A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI848486B (zh) | 組織選擇性轉基因表現 | |
| CN110269047A (zh) | 人源化IL-4和IL-4Rα动物 | |
| JP2017514501A5 (https=) | ||
| JP2011501652A5 (https=) | ||
| CN106282122A (zh) | 一种非人哺乳动物恐惧症或其相关疾病动物模型的建立方法及其用途 | |
| JP4468429B2 (ja) | ニューロンニコチン性アセチルコリン受容体のβ2−サブユニットの調節配列及びこれをコードする配列を含むゲノムDNA断片、及びこれらの断片又は突然変異断片を用いて作製されたトランスジェニック動物 | |
| JP2019505216A5 (https=) | ||
| JP5393492B2 (ja) | 動物モデル、その作製方法、及び、それを用いた薬物候補のスクリーニング方法 | |
| JP2022517101A5 (https=) | ||
| US20230123787A1 (en) | Rodent model of mood disorders | |
| JP7504030B2 (ja) | 進行性骨化性線維異形成症のげっ歯類モデル | |
| JP2001500385A (ja) | 組換え血管内皮増殖因子b(vegf−b)dnaによるトランスジェニック動物およびその利用方法 | |
| JP2024500153A5 (https=) | ||
| KR100699453B1 (ko) | 신경퇴행성 질환용 모델로서의 형질전환 동물 | |
| WO2021070866A1 (ja) | アルツハイマー病モデル非ヒト動物及びその製造方法 | |
| CN113082193B (zh) | 受调节的内分泌特异性蛋白18及其基因的用途 | |
| JP2018201495A (ja) | 多系統萎縮症モデル動物 | |
| JPH0851890A (ja) | プロテオリピド蛋白質が欠損しているトランスジエニツク動物およびそのような動物の作製方法 | |
| CN1952159A (zh) | 用于taar1功能的基因敲除动物 | |
| ES2257902B1 (es) | Modelo de animal transgenico para el desarrollo de nuevas aproximaciones terapeuticas. | |
| JP6323876B2 (ja) | ノックインマウス | |
| JP2007129938A (ja) | ノックアウトマウス | |
| JP2006314242A (ja) | 哺乳動物由来の変異sdhc遺伝子を有する遺伝子組み換え動物 | |
| KR20150122373A (ko) | 뇌하수체 종양 동물모델 | |
| JP2006158397A (ja) | sca2遺伝子の病原性変異体を発現するF066トランスジェニックマウス |