JP2024500153A5 - - Google Patents
Info
- Publication number
- JP2024500153A5 JP2024500153A5 JP2023537555A JP2023537555A JP2024500153A5 JP 2024500153 A5 JP2024500153 A5 JP 2024500153A5 JP 2023537555 A JP2023537555 A JP 2023537555A JP 2023537555 A JP2023537555 A JP 2023537555A JP 2024500153 A5 JP2024500153 A5 JP 2024500153A5
- Authority
- JP
- Japan
- Prior art keywords
- rodent
- gene
- humanized
- il7ra
- tslpr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063128258P | 2020-12-21 | 2020-12-21 | |
| US63/128,258 | 2020-12-21 | ||
| PCT/US2021/064270 WO2022140221A1 (en) | 2020-12-21 | 2021-12-20 | Non-human animals having a humanized tslp gene, a humanized tslp receptor gene, and/or a humanized il7ra gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500153A JP2024500153A (ja) | 2024-01-04 |
| JP2024500153A5 true JP2024500153A5 (https=) | 2024-12-27 |
Family
ID=80050757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023537555A Pending JP2024500153A (ja) | 2020-12-21 | 2021-12-20 | ヒト化ｔｓｌｐ遺伝子、ヒト化ｔｓｌｐ受容体遺伝子、及び／又はヒト化ｉｌ７ｒａ遺伝子を有する非ヒト動物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20220192165A1 (https=) |
| EP (1) | EP4262374A1 (https=) |
| JP (1) | JP2024500153A (https=) |
| KR (1) | KR20230124973A (https=) |
| CN (1) | CN116802200A (https=) |
| AU (1) | AU2021409632A1 (https=) |
| CA (1) | CA3171455A1 (https=) |
| IL (1) | IL303724A (https=) |
| WO (1) | WO2022140221A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023046201A1 (en) * | 2021-09-27 | 2023-03-30 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric genes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6586251B2 (en) | 2000-10-31 | 2003-07-01 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| ES2463476T3 (es) | 2004-10-19 | 2014-05-28 | Regeneron Pharmaceuticals, Inc. | Método para generar un ratón homocigótico para una modificación genética |
| EP4502152A3 (en) | 2009-10-06 | 2025-04-30 | Regeneron Pharmaceuticals, Inc. | Genetically modified mice and engraftment |
| US8962913B2 (en) * | 2012-06-18 | 2015-02-24 | Regeneron Pharmaceuticals, Inc. | Humanized IL-7 rodents |
| MX384291B (es) | 2013-02-20 | 2025-03-14 | Regeneron Pharma | Modificación genética de ratas. |
| DK3456831T3 (da) | 2013-04-16 | 2021-09-06 | Regeneron Pharma | Målrettet modifikation af rottegenom |
| TR201901782T4 (tr) | 2013-09-23 | 2019-03-21 | Regeneron Pharma | İnsanlaştirilmiş bi̇r si̇nyal düzenleyi̇ci̇ protei̇n geni̇ne sahi̇p olan i̇nsan dişi hayvanlar. |
| NO2785538T3 (https=) * | 2014-05-07 | 2018-08-04 | ||
| HRP20210650T1 (hr) * | 2015-09-09 | 2021-05-28 | Novartis Ag | Protutijela koja vežu timusni stromalni limfopoetin (tslp) i postupci uporabe protutijela |
| WO2018177441A1 (en) | 2017-03-31 | 2018-10-04 | Beijing Biocytogen Co., Ltd | GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPα |
| WO2020008066A1 (en) * | 2018-07-06 | 2020-01-09 | Institut Pasteur | Human immune system mouse model |
| CN109678957B (zh) * | 2018-12-06 | 2021-04-06 | 浙江工业大学 | 一种抗人tslp单克隆抗体及其制备与应用 |
| CN111808882B (zh) * | 2020-09-01 | 2020-12-29 | 北京百奥赛图基因生物技术有限公司 | Il7r基因人源化改造的动物模型的构建方法及其应用 |
-
2021
- 2021-12-20 JP JP2023537555A patent/JP2024500153A/ja active Pending
- 2021-12-20 CA CA3171455A patent/CA3171455A1/en active Pending
- 2021-12-20 CN CN202180086511.8A patent/CN116802200A/zh active Pending
- 2021-12-20 EP EP21848364.2A patent/EP4262374A1/en active Pending
- 2021-12-20 KR KR1020237024353A patent/KR20230124973A/ko active Pending
- 2021-12-20 US US17/555,550 patent/US20220192165A1/en not_active Abandoned
- 2021-12-20 IL IL303724A patent/IL303724A/en unknown
- 2021-12-20 AU AU2021409632A patent/AU2021409632A1/en active Pending
- 2021-12-20 WO PCT/US2021/064270 patent/WO2022140221A1/en not_active Ceased
-
2025
- 2025-04-25 US US19/189,370 patent/US20250248377A1/en active Pending
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