|
US3662333A
(en)
|
1970-09-08 |
1972-05-09 |
Bendix Corp |
Hydraulic accumulator charge detector and indicating system
|
|
JPS5123197U
(https=)
|
1974-08-12 |
1976-02-20 |
|
|
|
WO1985000043A1
(en)
|
1983-06-15 |
1985-01-03 |
Kingdon Craig R |
Peptides, pharmaceutical compositions, genes, vectors, host organisms, processes for their production and diagnostic reagents
|
|
JPS62129297A
(ja)
|
1985-08-09 |
1987-06-11 |
Toyo Jozo Co Ltd |
カルシトニン遺伝子関連ペプチド誘導体
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
US5266561A
(en)
|
1988-01-11 |
1993-11-30 |
Amylin Pharmaceuticals, Inc. |
Treatment of type 2 diabetes mellitus
|
|
US5364841A
(en)
|
1988-01-11 |
1994-11-15 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and essential hypertension and related disorders
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
DE69433747D1
(de)
|
1994-08-16 |
2004-06-03 |
Human Genome Sciences Inc |
Calcitoninrezeptor
|
|
FR2732221B1
(fr)
|
1995-03-28 |
1997-04-25 |
Oreal |
Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue
|
|
EP0851759A4
(en)
|
1995-09-05 |
2000-12-06 |
Smithkline Beecham Corp |
COMPOUNDS AND RELATED METHODS
|
|
JP2002511836A
(ja)
|
1996-09-09 |
2002-04-16 |
スミスクライン・ビーチャム・コーポレイション |
化合物および方法
|
|
DE59711622D1
(de)
|
1996-09-10 |
2004-06-17 |
Boehringer Ingelheim Pharma |
Abgewandelte aminosäuren, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
WO1998056779A1
(en)
|
1997-06-13 |
1998-12-17 |
Smithkline Beecham Corporation |
4-sulfinyl benzamides as calcitonin gene-related peptide receptor antagonists
|
|
US6956107B2
(en)
|
1998-02-20 |
2005-10-18 |
Tanox, Inc. |
Inhibitors of complement activation
|
|
US6552043B1
(en)
|
1998-09-30 |
2003-04-22 |
Merck Sharpe & Dohme Ltd. |
Benzimidazolinyl piperidines as CGRP ligands
|
|
WO2000023579A1
(en)
|
1998-10-22 |
2000-04-27 |
The Regents Of The University Of California |
Functionally assembled antigen-specific intact recombinant antibody and a method for production thereof
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
EP1031350A1
(en)
|
1999-02-23 |
2000-08-30 |
Warner-Lambert Company |
Use of a gabapentin-analog for the manufacture of a medicament for preventing and treating visceral pain
|
|
US6313097B1
(en)
|
1999-03-02 |
2001-11-06 |
Boehringer Ingelheim Pharma Kg |
Antagonists of calcitonin gene-related peptide
|
|
US6521609B1
(en)
|
1999-08-10 |
2003-02-18 |
Boehringer Ingelheim Pharma Kg |
Use of CGRP antagonists and CGRP release inhibitors for combating menopausal hot flushes
|
|
SK287400B6
(sk)
|
1999-09-25 |
2010-08-09 |
University Of Iowa Research Foundation |
Prostriedok s obsahom imunostimulačnej nukleovej kyseliny a jeho použitie na stimuláciu imunitnej reakcie
|
|
EP2341075A1
(en)
|
2000-03-01 |
2011-07-06 |
MedImmune, LLC |
Antibodies binding to the f protein of a respiratory syncytial virus (rsv)
|
|
US6406863B1
(en)
|
2000-06-23 |
2002-06-18 |
Genetastix Corporation |
High throughput generation and screening of fully human antibody repertoire in yeast
|
|
US20020162125A1
(en)
|
2001-03-06 |
2002-10-31 |
Anne-Marie Salmon |
Methods and compositions for the modulation of neurogenic inflammatory pain and physical opiate withdrawal
|
|
US20030181462A1
(en)
|
2001-08-17 |
2003-09-25 |
Boehringer Ingelheim Pharma Kg |
Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine
|
|
CA2471833A1
(en)
|
2001-11-26 |
2003-06-05 |
Protemix Corporation Limited |
Methods of compositions for normalizing lipid levels in mammalian tissues
|
|
ES2327830T3
(es)
|
2002-03-29 |
2009-11-04 |
Schering Corporation |
Anticuerpos monoclonales humanos anti-interleuquina-5 y metodos y composiciones que los contienen.
|
|
US7879991B2
(en)
|
2002-05-06 |
2011-02-01 |
Noxxon Pharma Ag |
CGRP binding nucleic acids
|
|
US20040110170A1
(en)
|
2002-05-18 |
2004-06-10 |
The Regents Of The University Of California |
Cloning and characterization of calcitonin gene related peptide receptors
|
|
US7345065B2
(en)
|
2002-05-21 |
2008-03-18 |
Allergan, Inc. |
Methods and compositions for alleviating pain
|
|
BRPI0311812B8
(pt)
|
2002-06-05 |
2021-05-25 |
Bristol Myers Squibb Co |
antagonistas de receptor de peptídeo relacionado com o gene de calcitonina, composição farmacêutica e seu uso
|
|
ES2263984T3
(es)
|
2002-06-28 |
2006-12-16 |
Domantis Limited |
Ligandos doble-especificos con una vida media serica aumentada.
|
|
CA2495498C
(en)
|
2002-08-12 |
2014-04-15 |
Birkir Sveinsson |
Use of cgrp antagonist compounds for treatment of psoriasis
|
|
UA80447C2
(en)
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
|
DE10250082A1
(de)
|
2002-10-25 |
2004-05-13 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
DE60333228D1
(de)
|
2002-12-02 |
2010-08-12 |
Amgen Fremont Inc |
Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen
|
|
CN101014364B
(zh)
|
2002-12-24 |
2012-01-18 |
里纳特神经系统学公司 |
抗ngf抗体及其使用方法
|
|
JP4673296B2
(ja)
|
2003-03-14 |
2011-04-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
アリールスピロヒダントインｃｇｒｐ受容体拮抗物質
|
|
CA2519475A1
(en)
|
2003-03-14 |
2004-09-30 |
Merck & Co., Inc. |
Bicyclic anilide spirohydantoin cgrp receptor antagonists
|
|
US7205293B2
(en)
|
2003-03-14 |
2007-04-17 |
Merck & Co., Inc. |
Benodiazepine spirohydantoin CGRP receptor antagonists
|
|
AU2004221891B2
(en)
|
2003-03-14 |
2009-11-19 |
Merck Sharp & Dohme Corp. |
Monocyclic anilide spirohydantoin CGRP receptor antagonists
|
|
CA2518830A1
(en)
|
2003-03-14 |
2004-09-30 |
Merck & Co., Inc. |
Carboxamide spirohydantoin cgrp receptor antagonists
|
|
JP4705908B2
(ja)
|
2003-04-15 |
2011-06-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Ｃｇｒｐ受容体拮抗薬
|
|
JO2355B1
(en)
|
2003-04-15 |
2006-12-12 |
ميرك شارب اند دوم كوربوريشن |
Hereditary calcitonin polypeptide receptor antagonists
|
|
WO2004097421A2
(en)
|
2003-04-29 |
2004-11-11 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with calcitonin receptor-like receptor (calcrl)
|
|
US20070065463A1
(en)
|
2003-06-20 |
2007-03-22 |
Ronald Aung-Din |
Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
|
|
CN100418948C
(zh)
|
2003-07-15 |
2008-09-17 |
麦克公司 |
羟基吡啶cgrp受体抗拮抗剂
|
|
PT1678314E
(pt)
|
2003-10-22 |
2012-11-27 |
Keck Graduate Inst |
Métodos de síntese de polipéptidos heteromultiméricos em levedura utilizando uma estratégia de conjugação haplóide
|
|
WO2005041757A2
(en)
|
2003-10-29 |
2005-05-12 |
University Of Rochester |
Detection of neuropeptides associated with pelvic pain disorders and uses thereof
|
|
JP2007517911A
(ja)
|
2004-01-13 |
2007-07-05 |
バソジェニックス ファーマシューティカルズ， インコーポレイテッド |
心臓血管の適応症および腎臓の適応症に対してｃｇｒｐを使用する方法
|
|
DE102004015723A1
(de)
|
2004-03-29 |
2005-10-20 |
Boehringer Ingelheim Pharma |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
DE102004018794A1
(de)
|
2004-04-15 |
2005-10-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
US7279471B2
(en)
|
2004-04-15 |
2007-10-09 |
Boehringer Ingelheim International Gmbh |
Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
|
|
TWI432196B
(zh)
|
2005-01-18 |
2014-04-01 |
Euro Celtique Sa |
內臟痛的治療
|
|
EP1770091A1
(de)
|
2005-09-29 |
2007-04-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
|
WO2007025212A2
(en)
|
2005-08-25 |
2007-03-01 |
Wex Pharmaceuticals, Inc. |
Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment
|
|
US8168592B2
(en)
|
2005-10-21 |
2012-05-01 |
Amgen Inc. |
CGRP peptide antagonists and conjugates
|
|
US20070108378A1
(en)
|
2005-11-14 |
2007-05-17 |
Toru Terabayashi |
High pressure optical cell for a downhole optical fluid analyzer
|
|
MY153249A
(en)
|
2005-11-14 |
2015-01-29 |
Rinat Neuroscience Corp |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
|
ATE493412T1
(de)
|
2005-11-18 |
2011-01-15 |
Merck Sharp & Dohme |
Spirohydantoin-aryl-cgrp-rezeptorantagonisten
|
|
WO2007076336A1
(en)
|
2005-12-22 |
2007-07-05 |
Eli Lilly And Company |
Treatment of migraine with anti-cgrp antibodies
|
|
US9074352B2
(en)
|
2006-03-27 |
2015-07-07 |
John R. Ramun |
Universal control scheme for mobile hydraulic equipment and method for achieving the same
|
|
PE20080370A1
(es)
|
2006-06-08 |
2008-06-13 |
Boehringer Ingelheim Int |
Derivados de quinazolinona como antagonistas de cgrp
|
|
JP5511379B2
(ja)
|
2006-07-21 |
2014-06-04 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Ｃｇｒｐレセプターアンタゴニスト
|
|
JP2008268874A
(ja)
|
2007-03-23 |
2008-11-06 |
Nec Corp |
標識体及びその製造方法
|
|
HUE032563T2
(en)
|
2007-05-21 |
2017-09-28 |
Alderbio Holdings Llc |
Antibodies to IL-6 and their use
|
|
KR20170036814A
(ko)
|
2007-05-21 |
2017-04-03 |
앨더바이오 홀딩스 엘엘씨 |
신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
|
|
CA2716424C
(en)
|
2008-03-04 |
2015-04-28 |
Pfizer Limited |
Methods of treating chronic pain
|
|
DK2265288T3
(en)
|
2008-03-04 |
2016-06-06 |
Labrys Biologics Inc |
Methods for the treatment of inflammatory pain
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
KR101519192B1
(ko)
|
2009-08-28 |
2015-05-11 |
리나트 뉴로사이언스 코프. |
칼시토닌 유전자-관련된 펩티드에 대해 지시된 길항제 항체의 투여에 의한 내장 통증의 치료 방법
|
|
AR081434A1
(es)
|
2010-06-10 |
2012-08-29 |
Lilly Co Eli |
Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
|
|
NZ717704A
(en)
|
2011-05-20 |
2022-08-26 |
H Lundbeck As |
Use of anti-cgrp or anti-cgrp-r antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea
|
|
TWI685505B
(zh)
|
2011-05-20 |
2020-02-21 |
美商艾爾德生物控股有限責任公司 |
抗降血鈣素基因相關胜肽（ａｎｔｉ-ｃｇｒｐ）組成物及其用途
|
|
AU2012258980B8
(en)
*
|
2011-05-20 |
2017-06-15 |
H. Lundbeck A/S |
Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
|
|
US20170114122A1
(en)
|
2015-10-23 |
2017-04-27 |
Alderbio Holdings Llc |
Regulation of glucose metabolism using anti-cgrp antibodies
|
|
PE20161439A1
(es)
|
2014-03-21 |
2017-01-26 |
Teva Pharmaceuticals Int Gmbh |
Anticuerpos antagonistas dirigidos contra el peptido relacionado con el gen de calcitonina y metodos que usan los mismos
|
|
GB201408469D0
(en)
|
2014-05-13 |
2014-06-25 |
Obs Medical Ltd |
Method and apparatus for monitoring patient status
|
|
TWI799849B
(zh)
|
2015-04-24 |
2023-04-21 |
美商安美基公司 |
治療或預防偏頭痛之方法
|
|
AR104847A1
(es)
|
2015-06-17 |
2017-08-16 |
Lilly Co Eli |
Formulación de anticuerpo anti-cgrp
|
|
EA201890578A1
(ru)
|
2015-09-24 |
2018-12-28 |
Тева Фармасьютикалз Интернэшнл Гмбх |
Предотвращение, лечение и снижение (персистирующей) посттравматической головной боли
|
|
WO2017186928A1
(en)
*
|
2016-04-29 |
2017-11-02 |
Curevac Ag |
Rna encoding an antibody
|
|
WO2018055574A1
(en)
*
|
2016-09-23 |
2018-03-29 |
Teva Pharmaceuticals International Gmbh |
Treating refractory migraine
|
|
PE20211708A1
(es)
|
2019-01-08 |
2021-09-01 |
H Lundbeck As |
Tratamiento de cefalea por uso excesivo de medicamentos usando anticuerpos anticgrp o anti-cgrp-r
|
|
CN113227140A
(zh)
|
2019-01-08 |
2021-08-06 |
H.隆德贝克有限公司 |
使用抗cgrp抗体急性治疗和快速治疗头痛
|