|
US3662333A
(en)
|
1970-09-08 |
1972-05-09 |
Bendix Corp |
Hydraulic accumulator charge detector and indicating system
|
|
JPS5123197U
(https=)
|
1974-08-12 |
1976-02-20 |
|
|
|
DE3484377D1
(de)
|
1983-06-15 |
1991-05-08 |
Celltech Ltd |
Peptide, pharmazeutische zusammensetzungen, gene, vektoren, wirtorganismen, verfahren zu deren herstellung und diagnostische reagenzien.
|
|
JPS62129297A
(ja)
|
1985-08-09 |
1987-06-11 |
Toyo Jozo Co Ltd |
カルシトニン遺伝子関連ペプチド誘導体
|
|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・2・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
|
US5266561A
(en)
|
1988-01-11 |
1993-11-30 |
Amylin Pharmaceuticals, Inc. |
Treatment of type 2 diabetes mellitus
|
|
US5364841A
(en)
|
1988-01-11 |
1994-11-15 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and essential hypertension and related disorders
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
EP0777684B1
(en)
|
1994-08-16 |
2004-04-28 |
Human Genome Sciences, Inc. |
Calcitonin receptor
|
|
FR2732221B1
(fr)
|
1995-03-28 |
1997-04-25 |
Oreal |
Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue
|
|
JPH11512396A
(ja)
|
1995-09-05 |
1999-10-26 |
スミスクライン・ビーチャム・コーポレイション |
化合物および方法
|
|
WO1998009630A1
(en)
|
1996-09-09 |
1998-03-12 |
Smithkline Beecham Corporation |
Compounds and methods
|
|
SK285631B6
(sk)
|
1996-09-10 |
2007-05-03 |
Dr. Karl Thomae Gmbh |
Modifikované aminokyseliny, farmaceutický prostriedok s ich obsahom a ich použitie
|
|
WO1998056779A1
(en)
|
1997-06-13 |
1998-12-17 |
Smithkline Beecham Corporation |
4-sulfinyl benzamides as calcitonin gene-related peptide receptor antagonists
|
|
US6956107B2
(en)
|
1998-02-20 |
2005-10-18 |
Tanox, Inc. |
Inhibitors of complement activation
|
|
WO2000018764A1
(en)
|
1998-09-30 |
2000-04-06 |
Merck Sharp & Dohme Limited |
Benzimidazolinyl piperidines as cgrp ligands
|
|
AU1219000A
(en)
|
1998-10-22 |
2000-05-08 |
Regents Of The University Of California, The |
Functionally assembled antigen-specific intact recombinant antibody and a methodfor production thereof
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
EP1031350A1
(en)
|
1999-02-23 |
2000-08-30 |
Warner-Lambert Company |
Use of a gabapentin-analog for the manufacture of a medicament for preventing and treating visceral pain
|
|
US6313097B1
(en)
|
1999-03-02 |
2001-11-06 |
Boehringer Ingelheim Pharma Kg |
Antagonists of calcitonin gene-related peptide
|
|
US6521609B1
(en)
|
1999-08-10 |
2003-02-18 |
Boehringer Ingelheim Pharma Kg |
Use of CGRP antagonists and CGRP release inhibitors for combating menopausal hot flushes
|
|
NZ517929A
(en)
|
1999-09-25 |
2004-02-27 |
Univ Iowa Res Found |
Immunostimulatory nucleic acids
|
|
DK1259547T3
(da)
|
2000-03-01 |
2012-10-15 |
Medimmune Inc |
Højpotente, rekombinante antistoffer og fremgangsmåde til fremstilling heraf
|
|
US6406863B1
(en)
|
2000-06-23 |
2002-06-18 |
Genetastix Corporation |
High throughput generation and screening of fully human antibody repertoire in yeast
|
|
US20020162125A1
(en)
|
2001-03-06 |
2002-10-31 |
Anne-Marie Salmon |
Methods and compositions for the modulation of neurogenic inflammatory pain and physical opiate withdrawal
|
|
US20030181462A1
(en)
|
2001-08-17 |
2003-09-25 |
Boehringer Ingelheim Pharma Kg |
Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine
|
|
EP1461068A4
(en)
|
2001-11-26 |
2006-03-29 |
Protemix Corp Ltd |
METHOD AND COMPOSITIONS FOR NORMALIZING LIPID MIRRORS IN MIRACLE TISSUE
|
|
PT1527100E
(pt)
|
2002-03-29 |
2009-08-25 |
Schering Corp |
Anticorpos monoclonais humanos para interleucina-5 e métodos e composições compreendendo os mesmos
|
|
EP1501929B1
(de)
|
2002-05-06 |
2013-03-27 |
Noxxon Pharma AG |
Cgrp bindende nukleinsäuren
|
|
US20040110170A1
(en)
|
2002-05-18 |
2004-06-10 |
The Regents Of The University Of California |
Cloning and characterization of calcitonin gene related peptide receptors
|
|
US7345065B2
(en)
|
2002-05-21 |
2008-03-18 |
Allergan, Inc. |
Methods and compositions for alleviating pain
|
|
RS52552B
(sr)
|
2002-06-05 |
2013-04-30 |
Bristol-Myers Squibb Company |
Antagonisti, peptidnog receptora koji je u vezi sa kalcitoninskim genom
|
|
AU2003244817B2
(en)
|
2002-06-28 |
2010-08-26 |
Domantis Limited |
Antigen-binding immunoglobulin single variable domains and dual-specific constructs
|
|
EA008744B1
(ru)
|
2002-08-12 |
2007-08-31 |
Актавис Груп Хф. |
Применение соединений антагонистов кальцитонин генсвязанного пептида (cgrp) для лечения псориаза
|
|
UA80447C2
(en)
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
|
DE10250082A1
(de)
|
2002-10-25 |
2004-05-13 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
US7285269B2
(en)
|
2002-12-02 |
2007-10-23 |
Amgen Fremont, Inc. |
Antibodies directed to tumor necrosis factor
|
|
DK2270048T3
(en)
|
2002-12-24 |
2016-01-18 |
Rinat Neuroscience Corp |
Anti-NGF antibodies and methods for their use
|
|
EP1606264B1
(en)
|
2003-03-14 |
2012-05-02 |
Merck Sharp & Dohme Corp. |
Monocyclic anilide spirohydantoin cgrp receptor antagonists
|
|
AU2004222378B2
(en)
|
2003-03-14 |
2008-08-14 |
Merck Sharp & Dohme Corp. |
Carboxamide spirohydantoin CGRP receptor antagonists
|
|
AU2004222328B2
(en)
|
2003-03-14 |
2009-10-08 |
Merck Sharp & Dohme Corp. |
Aryl spirohydantoin CGRP receptor antagonists
|
|
ATE394400T1
(de)
|
2003-03-14 |
2008-05-15 |
Merck & Co Inc |
Bicyclische anilidspirohydantoine als cgrp- rezeptorantagonisten
|
|
CA2519515A1
(en)
|
2003-03-14 |
2004-10-14 |
Merck & Co., Inc. |
Benodiazepine spirohydantoin cgrp receptor antagonists
|
|
ATE466860T1
(de)
|
2003-04-15 |
2010-05-15 |
Merck Sharp & Dohme |
Cgrp-rezeptorantagonisten
|
|
JO2355B1
(en)
|
2003-04-15 |
2006-12-12 |
ميرك شارب اند دوم كوربوريشن |
Hereditary calcitonin polypeptide receptor antagonists
|
|
WO2004097421A2
(en)
|
2003-04-29 |
2004-11-11 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with calcitonin receptor-like receptor (calcrl)
|
|
US20070065463A1
(en)
|
2003-06-20 |
2007-03-22 |
Ronald Aung-Din |
Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
|
|
WO2005009962A1
(en)
|
2003-07-15 |
2005-02-03 |
Merck & Co., Inc. |
Hydroxypyridine cgrp receptor antagonists
|
|
CA2541651C
(en)
|
2003-10-22 |
2011-05-24 |
Keck Graduate Institute |
Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy
|
|
US20080070239A1
(en)
|
2003-10-29 |
2008-03-20 |
University Of Rochester |
Detection of neureopeptides associated with pelvic pain disorders and uses thereof
|
|
JP2007517911A
(ja)
|
2004-01-13 |
2007-07-05 |
バソジェニックス ファーマシューティカルズ, インコーポレイテッド |
心臓血管の適応症および腎臓の適応症に対してcgrpを使用する方法
|
|
DE102004015723A1
(de)
|
2004-03-29 |
2005-10-20 |
Boehringer Ingelheim Pharma |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
DE102004018794A1
(de)
|
2004-04-15 |
2005-10-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
US7279471B2
(en)
|
2004-04-15 |
2007-10-09 |
Boehringer Ingelheim International Gmbh |
Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
|
|
TWI432196B
(zh)
|
2005-01-18 |
2014-04-01 |
Euro Celtique Sa |
內臟痛的治療
|
|
EP1770091A1
(de)
|
2005-09-29 |
2007-04-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
|
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
|
WO2007025212A2
(en)
|
2005-08-25 |
2007-03-01 |
Wex Pharmaceuticals, Inc. |
Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment
|
|
US8168592B2
(en)
|
2005-10-21 |
2012-05-01 |
Amgen Inc. |
CGRP peptide antagonists and conjugates
|
|
US20070108378A1
(en)
|
2005-11-14 |
2007-05-17 |
Toru Terabayashi |
High pressure optical cell for a downhole optical fluid analyzer
|
|
EP3069731A1
(en)
|
2005-11-14 |
2016-09-21 |
Labrys Biologics Inc. |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
|
JP2009515971A
(ja)
|
2005-11-18 |
2009-04-16 |
メルク エンド カムパニー インコーポレーテッド |
スピロヒダントインアリールcgrp受容体アンタゴニスト
|
|
WO2007076336A1
(en)
|
2005-12-22 |
2007-07-05 |
Eli Lilly And Company |
Treatment of migraine with anti-cgrp antibodies
|
|
US9074352B2
(en)
|
2006-03-27 |
2015-07-07 |
John R. Ramun |
Universal control scheme for mobile hydraulic equipment and method for achieving the same
|
|
KR20090021214A
(ko)
|
2006-06-08 |
2009-02-27 |
베링거 인겔하임 인터내셔날 게엠베하 |
Cgrp-길항제에 의한 위장 장애의 치료
|
|
DE602007006961D1
(de)
|
2006-07-21 |
2010-07-15 |
Vertex Pharma |
Cgrp-rezeptorantagonisten
|
|
JP2008268874A
(ja)
|
2007-03-23 |
2008-11-06 |
Nec Corp |
標識体及びその製造方法
|
|
DK2164514T3
(en)
|
2007-05-21 |
2017-02-27 |
Alderbio Holdings Llc |
Antibodies to IL-6 and its use
|
|
KR20170036814A
(ko)
|
2007-05-21 |
2017-04-03 |
앨더바이오 홀딩스 엘엘씨 |
신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
|
|
RU2522493C2
(ru)
|
2008-03-04 |
2014-07-20 |
Пфайзер Лимитед |
Способы лечения хронической боли
|
|
WO2009109908A1
(en)
|
2008-03-04 |
2009-09-11 |
Pfizer Limited |
Methods of treating inflammatory pain
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
CN102740884A
(zh)
|
2009-08-28 |
2012-10-17 |
瑞纳神经科学公司 |
通过施用针对降钙素基因相关肽的拮抗性抗体来治疗内脏痛的方法
|
|
AR081434A1
(es)
|
2010-06-10 |
2012-08-29 |
Lilly Co Eli |
Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
|
|
PE20141787A1
(es)
|
2011-05-20 |
2014-12-07 |
Alderbio Holdings Llc |
Composiciones anti-cgrp y uso de las mismas
|
|
TWI705825B
(zh)
|
2011-05-20 |
2020-10-01 |
美商艾爾德生物控股有限責任公司 |
抗降血鈣素基因相關胜肽(anti-cgrp)或抗降血鈣素基因相關胜肽受器(anti-cgrp-r)抗體或抗體片段治療或預防慢性及急性型腹瀉之用途
|
|
CN107827982B
(zh)
|
2011-05-20 |
2021-07-06 |
H.伦德贝克公司 |
抗cgrp抗体和抗体片段用于在有需要的受试者中预防或抑制畏光或厌光的用途
|
|
US20170114122A1
(en)
|
2015-10-23 |
2017-04-27 |
Alderbio Holdings Llc |
Regulation of glucose metabolism using anti-cgrp antibodies
|
|
AU2015230933B2
(en)
*
|
2014-03-21 |
2020-08-13 |
Teva Pharmaceuticals International Gmbh |
Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
|
|
GB201408469D0
(en)
|
2014-05-13 |
2014-06-25 |
Obs Medical Ltd |
Method and apparatus for monitoring patient status
|
|
TWI799849B
(zh)
|
2015-04-24 |
2023-04-21 |
美商安美基公司 |
治療或預防偏頭痛之方法
|
|
AR104847A1
(es)
|
2015-06-17 |
2017-08-16 |
Lilly Co Eli |
Formulación de anticuerpo anti-cgrp
|
|
MX2018003713A
(es)
|
2015-09-24 |
2018-08-15 |
Teva Pharmaceuticals Int Gmbh |
Prevencion, tratamiento y reduccion del dolor de cabeza postraumatico (persistente).
|
|
EP3448427A1
(en)
*
|
2016-04-29 |
2019-03-06 |
CureVac AG |
Rna encoding an antibody
|
|
CN109952314A
(zh)
*
|
2016-09-23 |
2019-06-28 |
泰瓦制药国际有限公司 |
治疗难治性偏头痛
|
|
WO2020146527A1
(en)
|
2019-01-08 |
2020-07-16 |
Alder Biopharmaceuticals, Inc. |
Acute treatment and rapid treatment of headache using anti-cgrp antibodies
|
|
WO2020146535A1
(en)
|
2019-01-08 |
2020-07-16 |
Alder Biopharmaceuticals, Inc. |
Treatment of medication overuse headache using anti-cgrp or anti-cgrp-r antibodies
|