JP2022514381A5 - - Google Patents
Info
- Publication number
- JP2022514381A5 JP2022514381A5 JP2021535670A JP2021535670A JP2022514381A5 JP 2022514381 A5 JP2022514381 A5 JP 2022514381A5 JP 2021535670 A JP2021535670 A JP 2021535670A JP 2021535670 A JP2021535670 A JP 2021535670A JP 2022514381 A5 JP2022514381 A5 JP 2022514381A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- administration
- crazakizumab
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783136P | 2018-12-20 | 2018-12-20 | |
| US62/783,136 | 2018-12-20 | ||
| US201962855993P | 2019-06-01 | 2019-06-01 | |
| US62/855,993 | 2019-06-01 | ||
| PCT/US2019/068103 WO2020132600A1 (en) | 2018-12-20 | 2019-12-20 | Clazakizumab in the treatment of chronic antibody-mediated rejection of organ transplant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514381A JP2022514381A (ja) | 2022-02-10 |
| JP2022514381A5 true JP2022514381A5 (enExample) | 2022-12-19 |
Family
ID=71101983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021535670A Pending JP2022514381A (ja) | 2018-12-20 | 2019-12-20 | 臓器移植の慢性抗体介在性拒絶反応の処置でのクラザキズマブ |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20220073605A1 (enExample) |
| EP (1) | EP3897718A4 (enExample) |
| JP (1) | JP2022514381A (enExample) |
| KR (1) | KR20210106521A (enExample) |
| CN (1) | CN113194996B (enExample) |
| AU (1) | AU2019404553A1 (enExample) |
| BR (1) | BR112021010615A2 (enExample) |
| CA (1) | CA3121934A1 (enExample) |
| WO (1) | WO2020132600A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
| CN114423782A (zh) * | 2019-09-04 | 2022-04-29 | 西达赛奈医疗中心 | 不含钙调磷酸酶抑制剂的ctla4-ig+抗il6/il6r用于对实体器官移植受体进行长期免疫抑制的用途 |
| WO2025122579A1 (en) * | 2023-12-04 | 2025-06-12 | Cedars-Sinai Medical Center | Cadherin 6 expression status in determination of renal fibrosis and related uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| CA1294215C (en) | 1986-10-27 | 1992-01-14 | Ze'ev Shaked | Pharmaceutical compositions of recombinant beta-interferon and formulation processes |
| CA1292686C (en) | 1986-10-27 | 1991-12-03 | Ze'ev Shaked | Pharmaceutical compositions of recombinant interleukin-2 and formulation process |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| CN101754772B (zh) * | 2007-05-21 | 2015-08-19 | 奥尔德生物控股有限责任公司 | 针对il-6的抗体及其用途 |
| US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
| WO2013150375A2 (en) * | 2012-04-04 | 2013-10-10 | Assistance Publique Hôpitaux De Paris | Endothelial cells activation biomarkers characterizing antibody mediated rejection and uses thereof |
| US9963513B2 (en) * | 2013-02-05 | 2018-05-08 | Engmab Sàrl | Method for the selection of antibodies against BCMA |
| ES2708655T3 (es) * | 2013-11-22 | 2019-04-10 | Shire Viropharma Inc | Métodos para tratar el rechazo mediado por anticuerpos en pacientes con trasplante de órganos con el inhibidor de la c1-esterasa |
| US11065319B2 (en) * | 2014-02-04 | 2021-07-20 | 3Dt Holdings, Llc | Methods for diagnosing and reducing incidences of cardiac allograft rejection |
| US20170022280A1 (en) * | 2015-07-24 | 2017-01-26 | Cedars-Sinai Medical Center | Method for treating antibody-mediated rejection post-transplantation |
| AU2019205488A1 (en) * | 2018-01-04 | 2020-07-23 | Cedars-Sinai Medical Center | Use of anti-iL-6 antibody, e.g., Clazakizumab for desensitization of solid organ transplant recipients and/or for preventing, stabilizing or reducing antibody mediated rejection (ABMR) |
| BR112021007633A2 (pt) * | 2018-11-08 | 2021-10-13 | Cedars-Sinai Medical Center | Uso de clazakizumabe para dessensibilizar e melhorar o transplante renal em pacientes sensibilizados por hla |
-
2019
- 2019-12-20 BR BR112021010615A patent/BR112021010615A2/pt unknown
- 2019-12-20 US US17/415,993 patent/US20220073605A1/en not_active Abandoned
- 2019-12-20 CN CN201980084166.7A patent/CN113194996B/zh active Active
- 2019-12-20 CA CA3121934A patent/CA3121934A1/en active Pending
- 2019-12-20 EP EP19900083.7A patent/EP3897718A4/en active Pending
- 2019-12-20 WO PCT/US2019/068103 patent/WO2020132600A1/en not_active Ceased
- 2019-12-20 KR KR1020217022866A patent/KR20210106521A/ko active Pending
- 2019-12-20 JP JP2021535670A patent/JP2022514381A/ja active Pending
- 2019-12-20 AU AU2019404553A patent/AU2019404553A1/en active Pending
-
2025
- 2025-03-17 US US19/081,867 patent/US20250263480A1/en active Pending
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