JP2022514085A5 - - Google Patents

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Publication number
JP2022514085A5
JP2022514085A5 JP2021535571A JP2021535571A JP2022514085A5 JP 2022514085 A5 JP2022514085 A5 JP 2022514085A5 JP 2021535571 A JP2021535571 A JP 2021535571A JP 2021535571 A JP2021535571 A JP 2021535571A JP 2022514085 A5 JP2022514085 A5 JP 2022514085A5
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JP
Japan
Prior art keywords
chromatography
cation exchange
mammalian cells
nacl
multimodal
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JP2021535571A
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English (en)
Japanese (ja)
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JP7458404B2 (ja
JP2022514085A (ja
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Priority claimed from PCT/US2019/067868 external-priority patent/WO2020132452A1/en
Publication of JP2022514085A publication Critical patent/JP2022514085A/ja
Publication of JP2022514085A5 publication Critical patent/JP2022514085A5/ja
Application granted granted Critical
Publication of JP7458404B2 publication Critical patent/JP7458404B2/ja
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JP2021535571A 2018-12-20 2019-12-20 イズロン酸－２－スルファターゼ免疫グロブリン融合タンパク質の精製 Active JP7458404B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862782834P 2018-12-20 2018-12-20
US62/782,834 2018-12-20
PCT/US2019/067868 WO2020132452A1 (en) 2018-12-20 2019-12-20 Purification of iduronate-2-sulfatase immunoglobulin fusion protein

Publications (3)

Publication Number Publication Date
JP2022514085A JP2022514085A (ja) 2022-02-09
JP2022514085A5 true JP2022514085A5 (https=) 2022-12-26
JP7458404B2 JP7458404B2 (ja) 2024-03-29

Family

ID=69187966

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021535571A Active JP7458404B2 (ja) 2018-12-20 2019-12-20 イズロン酸－２－スルファターゼ免疫グロブリン融合タンパク質の精製

Country Status (4)

Country Link
US (1) US20220002688A1 (https=)
EP (1) EP3898689A1 (https=)
JP (1) JP7458404B2 (https=)
WO (1) WO2020132452A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2485761B1 (en) 2009-10-09 2019-02-27 Armagen, Inc. Methods and compositions for increasing iduronate 2-sulfatase activity in the cns
EP4291246A4 (en) * 2021-02-11 2024-12-11 Denali Therapeutics Inc. ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF
EP4389772A4 (en) * 2021-08-18 2025-08-20 Joint Stock Company Generium TARGETED ADMINISTRATION OF THERAPEUTIC FERMENTS
CN118414350A (zh) * 2021-10-19 2024-07-30 阿特根公司 纯化具有igg fc结构域的融合蛋白的方法
CN114316072B (zh) * 2021-12-30 2024-01-19 华润昂德生物药业有限公司 重组人GLP-1-Fc融合蛋白的纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087510A2 (en) 2001-04-30 2002-11-07 Symbiontics, Inc. Subcellular targeting of therapeutic proteins
US7629309B2 (en) 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US20040005309A1 (en) 2002-05-29 2004-01-08 Symbiontics, Inc. Targeted therapeutic proteins
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
AU2002347910A1 (en) 2001-10-16 2003-04-28 Symbiontics Inc. Methods and compositions for targeting proteins across the blood brain barrier
EP1514106A4 (en) 2002-05-29 2007-05-09 Zystor Therapeutics Inc TARGETED THERAPEUTIC PROTEINS
US7388079B2 (en) 2002-11-27 2008-06-17 The Regents Of The University Of California Delivery of pharmaceutical agents via the human insulin receptor
US20050142141A1 (en) 2002-11-27 2005-06-30 Pardridge William M. Delivery of enzymes to the brain
CA2553955C (en) 2004-02-10 2012-08-28 Zystor Therapeutics, Inc. Acid alpha-glucosidase and fragments thereof
JP5627571B2 (ja) 2008-05-07 2014-11-19 バイオマリン ファーマシューティカル インコーポレイテッド リソソーム標的化ペプチドおよびその使用
EP2485761B1 (en) 2009-10-09 2019-02-27 Armagen, Inc. Methods and compositions for increasing iduronate 2-sulfatase activity in the cns
KR101976853B1 (ko) * 2010-05-25 2019-05-09 제넨테크, 인크. 폴리펩티드의 정제 방법
KR20230159646A (ko) 2010-06-25 2023-11-21 샤이어 휴먼 지네틱 테라피즈 인크. 이듀로네이트-2-설파타제의 cns 전달을 위한 방법들 및 조성물들
US8580922B2 (en) 2011-03-04 2013-11-12 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
KR101380740B1 (ko) * 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
WO2015009961A1 (en) * 2013-07-19 2015-01-22 Armagen Technologies, Inc. Compositions and methods related to structures that cross the blood brain barrier

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