JP2022512974A5 - - Google Patents
Info
- Publication number
- JP2022512974A5 JP2022512974A5 JP2021525082A JP2021525082A JP2022512974A5 JP 2022512974 A5 JP2022512974 A5 JP 2022512974A5 JP 2021525082 A JP2021525082 A JP 2021525082A JP 2021525082 A JP2021525082 A JP 2021525082A JP 2022512974 A5 JP2022512974 A5 JP 2022512974A5
- Authority
- JP
- Japan
- Prior art keywords
- synthesis
- ifn
- subject
- pharmaceutical composition
- repression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862757679P | 2018-11-08 | 2018-11-08 | |
| US62/757,679 | 2018-11-08 | ||
| US201962899584P | 2019-09-12 | 2019-09-12 | |
| US62/899,584 | 2019-09-12 | ||
| PCT/US2019/060285 WO2020097344A1 (en) | 2018-11-08 | 2019-11-07 | Synthetic immunomodulation with a crispr super-repressor in vivo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022512974A JP2022512974A (ja) | 2022-02-07 |
| JP2022512974A5 true JP2022512974A5 (https=) | 2023-06-12 |
Family
ID=70611555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525082A Pending JP2022512974A (ja) | 2018-11-08 | 2019-11-07 | 生体内ｃｒｉｓｐｒ超抑制因子による合成免疫調節 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11884925B2 (https=) |
| EP (1) | EP3877398A4 (https=) |
| JP (1) | JP2022512974A (https=) |
| KR (1) | KR20210102247A (https=) |
| CN (1) | CN113330023A (https=) |
| AU (1) | AU2019375914A1 (https=) |
| CA (1) | CA3119302A1 (https=) |
| IL (1) | IL283022A (https=) |
| SG (1) | SG11202104802RA (https=) |
| WO (1) | WO2020097344A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11773407B2 (en) | 2017-06-26 | 2023-10-03 | Arizona Board Of Regents On Behalf Of Arizona State University | CRISPR logic circuits for safer and controllable gene therapies |
| US20200123567A1 (en) | 2017-06-26 | 2020-04-23 | Samira Kiani | A universal platform to enhance crispr-based gene editing for in vivo therapies |
| WO2023288306A2 (en) * | 2021-07-16 | 2023-01-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Targeting myd88 gene in vitro and in vivo |
| EP4479538A4 (en) * | 2022-02-17 | 2026-01-28 | Syntax Bio Inc | CELL PROGRAMMING SYSTEMS AND ASSOCIATED PROCESSES |
| EP4711456A1 (en) * | 2024-09-11 | 2026-03-18 | GenCC GmbH & Co. KG | Method for the manufacture of individualized crispr/cas complexes and individualized crispr/cas complexes |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0931158A1 (en) | 1996-09-06 | 1999-07-28 | The Trustees Of The University Of Pennsylvania | An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase |
| US20030148986A1 (en) * | 2001-12-17 | 2003-08-07 | Cedars-Sinai Medical Center | Methods for treating vascular disease by inhibiting myeloid differentiation factor 88 |
| CN102166214B (zh) | 2011-03-02 | 2012-12-12 | 华中科技大学同济医学院附属同济医院 | 氨基噻唑类MyD88特异性抑制剂在医学上的用途 |
| US9228207B2 (en) * | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| JP6793547B2 (ja) * | 2013-12-12 | 2020-12-02 | ザ・ブロード・インスティテュート・インコーポレイテッド | 最適化機能ＣＲＩＳＰＲ−Ｃａｓ系による配列操作のための系、方法および組成物 |
| CN106456801A (zh) * | 2014-02-07 | 2017-02-22 | Sbi生物技术有限公司 | 用于治疗肿瘤的抑制性寡核苷酸 |
| WO2016049258A2 (en) * | 2014-09-25 | 2016-03-31 | The Broad Institute Inc. | Functional screening with optimized functional crispr-cas systems |
| WO2016094872A1 (en) * | 2014-12-12 | 2016-06-16 | The Broad Institute Inc. | Dead guides for crispr transcription factors |
| TWI906646B (zh) * | 2015-06-18 | 2025-12-01 | 美商博得學院股份有限公司 | 降低脫靶效應的ｃｒｉｓｐｒ酶突變 |
| US9790490B2 (en) * | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| NZ735250A (en) | 2015-07-08 | 2020-08-28 | Research & Business Found Sungkyunkwan Univ | Pyrrolidine carboxamido derivatives and methods for preparing and using the same |
| WO2017068077A1 (en) | 2015-10-20 | 2017-04-27 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods and products for genetic engineering |
| US11439692B2 (en) * | 2017-05-17 | 2022-09-13 | Modalis Therapeutics Corporation | Method of treating diseases associated with MYD88 pathways using CRISPR-GNDM system |
| US11773407B2 (en) * | 2017-06-26 | 2023-10-03 | Arizona Board Of Regents On Behalf Of Arizona State University | CRISPR logic circuits for safer and controllable gene therapies |
-
2019
- 2019-11-07 SG SG11202104802RA patent/SG11202104802RA/en unknown
- 2019-11-07 CN CN201980088195.0A patent/CN113330023A/zh active Pending
- 2019-11-07 EP EP19881214.1A patent/EP3877398A4/en not_active Withdrawn
- 2019-11-07 KR KR1020217017529A patent/KR20210102247A/ko not_active Ceased
- 2019-11-07 AU AU2019375914A patent/AU2019375914A1/en not_active Abandoned
- 2019-11-07 WO PCT/US2019/060285 patent/WO2020097344A1/en not_active Ceased
- 2019-11-07 US US17/292,407 patent/US11884925B2/en active Active
- 2019-11-07 JP JP2021525082A patent/JP2022512974A/ja active Pending
- 2019-11-07 CA CA3119302A patent/CA3119302A1/en active Pending
-
2021
- 2021-05-07 IL IL283022A patent/IL283022A/en unknown
-
2023
- 2023-12-11 US US18/535,658 patent/US20240117364A1/en active Pending
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