JP2022508218A5 - - Google Patents
Info
- Publication number
- JP2022508218A5 JP2022508218A5 JP2021529452A JP2021529452A JP2022508218A5 JP 2022508218 A5 JP2022508218 A5 JP 2022508218A5 JP 2021529452 A JP2021529452 A JP 2021529452A JP 2021529452 A JP2021529452 A JP 2021529452A JP 2022508218 A5 JP2022508218 A5 JP 2022508218A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxyphenyl
- difluoro
- amino
- oxadiazole
- pyrrolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862771196P | 2018-11-26 | 2018-11-26 | |
| US62/771,196 | 2018-11-26 | ||
| US201962819832P | 2019-03-18 | 2019-03-18 | |
| US62/819,832 | 2019-03-18 | ||
| PCT/US2019/062905 WO2020112583A1 (en) | 2018-11-26 | 2019-11-25 | Pyrrolidinone derivatives as formyl peptide 2 receptor agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022508218A JP2022508218A (ja) | 2022-01-19 |
| JP2022508218A5 true JP2022508218A5 (enExample) | 2022-12-02 |
| JP7398455B2 JP7398455B2 (ja) | 2023-12-14 |
Family
ID=68848531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529452A Active JP7398455B2 (ja) | 2018-11-26 | 2019-11-25 | ピラゾロンホルミルペプチド２受容体アゴニスト |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12281108B2 (enExample) |
| EP (1) | EP3887366B1 (enExample) |
| JP (1) | JP7398455B2 (enExample) |
| KR (1) | KR102877973B1 (enExample) |
| CN (1) | CN113166134B (enExample) |
| ES (1) | ES2964299T3 (enExample) |
| WO (1) | WO2020112583A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4178946A1 (en) * | 2020-07-09 | 2023-05-17 | Bristol-Myers Squibb Company | Oxopyrrolidine fpr2 agonists |
| ES2986512T3 (es) | 2020-07-09 | 2024-11-11 | Bristol Myers Squibb Co | Agonistas del receptor 2 del péptido formil pirazolona |
| WO2022035923A1 (en) * | 2020-08-12 | 2022-02-17 | Bristol-Myers Squibb Company | Oxopyrrolidine urea fpr2 agonists |
| WO2022076764A1 (en) * | 2020-10-09 | 2022-04-14 | Bristol-Myers Squibb Company | Aminoimidazole fpr2 agonists |
| JP7717816B2 (ja) * | 2021-01-21 | 2025-08-04 | バイオフロント セラピューティクス （ベイジン） カンパニー リミテッド | Ｆｐｒ１のモジュレーター及びそれを使用する方法 |
| JP7830488B2 (ja) * | 2021-01-21 | 2026-03-16 | ベイジン・ティアンタン・ホスピタル | Ｆｐｒ１のモジュレーター及びそれを使用する方法 |
| WO2022193187A1 (en) * | 2021-03-17 | 2022-09-22 | Biofront Ltd. (Cayman) | Modulators of fpr1 and methods of using same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3305763B1 (en) | 2013-11-28 | 2019-07-24 | Kyorin Pharmaceutical Co., Ltd. | Deuterated or isotopically labeled urea derivatives or pharmacologically acceptable salts thereof useful as fprl-1 agonists |
| AU2016266190A1 (en) | 2015-05-27 | 2018-01-18 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| WO2016189877A1 (en) | 2015-05-27 | 2016-12-01 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| KR20180081528A (ko) | 2015-11-24 | 2018-07-16 | 브리스톨-마이어스 스큅 컴퍼니 | 심장 질환의 치료를 위한 포르밀-펩타이드 수용체 2/리폭신 a4 수용체 (fpr2/alx) 타겟팅 |
| US10717708B2 (en) | 2015-12-10 | 2020-07-21 | Bristol-Myers Squibb Company | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| TW201815762A (zh) * | 2016-09-21 | 2018-05-01 | 德商歌林達有限公司 | 經尿素及苯基取代之６員環狀胺或內醯胺 |
| JP2020015664A (ja) * | 2016-11-21 | 2020-01-30 | 宇部興産株式会社 | 含窒素多環式ヘテロ環誘導体 |
| US11767291B2 (en) * | 2017-05-17 | 2023-09-26 | William Marsh Rice University | Preparation of secondary amines with electrophilic N-linchpin reagents |
| KR102615095B1 (ko) | 2017-06-09 | 2023-12-15 | 브리스톨-마이어스 스큅 컴퍼니 | 피페리디논 포르밀 펩티드 2 수용체 효능제 |
| JP7094989B2 (ja) | 2017-06-09 | 2022-07-04 | ブリストル－マイヤーズ スクイブ カンパニー | シクロプロピルウレアホルミルペプチド２受容体およびホルミルペプチド１受容体アゴニスト |
| EP3634956B1 (en) | 2017-06-09 | 2021-04-07 | Bristol-Myers Squibb Company | Aryl heterocyclic piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| WO2018227065A1 (en) | 2017-06-09 | 2018-12-13 | Bristol-Myers Squibb Company | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| WO2019173182A1 (en) | 2018-03-05 | 2019-09-12 | Bristol-Myers Squibb Company | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
| JP7494224B2 (ja) | 2019-06-18 | 2024-06-03 | ブリストル－マイヤーズ スクイブ カンパニー | ビアリールジアルキルホスフィンオキシドｆｐｒ２アゴニスト |
-
2019
- 2019-11-25 CN CN201980077329.9A patent/CN113166134B/zh active Active
- 2019-11-25 EP EP19818484.8A patent/EP3887366B1/en active Active
- 2019-11-25 ES ES19818484T patent/ES2964299T3/es active Active
- 2019-11-25 JP JP2021529452A patent/JP7398455B2/ja active Active
- 2019-11-25 WO PCT/US2019/062905 patent/WO2020112583A1/en not_active Ceased
- 2019-11-25 US US17/295,092 patent/US12281108B2/en active Active
- 2019-11-25 KR KR1020217019403A patent/KR102877973B1/ko active Active
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