JP2024521618A5 - - Google Patents

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Publication number
JP2024521618A5
JP2024521618A5 JP2023564563A JP2023564563A JP2024521618A5 JP 2024521618 A5 JP2024521618 A5 JP 2024521618A5 JP 2023564563 A JP2023564563 A JP 2023564563A JP 2023564563 A JP2023564563 A JP 2023564563A JP 2024521618 A5 JP2024521618 A5 JP 2024521618A5
Authority
JP
Japan
Prior art keywords
heptan
azaspiro
methanone
triazole
cyclopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023564563A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521618A (ja
JP7886348B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/060644 external-priority patent/WO2022223750A1/en
Publication of JP2024521618A publication Critical patent/JP2024521618A/ja
Publication of JP2024521618A5 publication Critical patent/JP2024521618A5/ja
Application granted granted Critical
Publication of JP7886348B2 publication Critical patent/JP7886348B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023564563A 2021-04-23 2022-04-22 複素環式化合物 Active JP7886348B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP21170090.1 2021-04-23
EP21170090 2021-04-23
CN2022083125 2022-03-25
CNPCT/CN2022/083125 2022-03-25
PCT/EP2022/060644 WO2022223750A1 (en) 2021-04-23 2022-04-22 Heterocyclic compounds

Publications (3)

Publication Number Publication Date
JP2024521618A JP2024521618A (ja) 2024-06-04
JP2024521618A5 true JP2024521618A5 (enExample) 2025-04-22
JP7886348B2 JP7886348B2 (ja) 2026-07-07

Family

ID=81750728

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023564563A Active JP7886348B2 (ja) 2021-04-23 2022-04-22 複素環式化合物

Country Status (16)

Country Link
US (1) US20240199587A1 (enExample)
EP (1) EP4326714A1 (enExample)
JP (1) JP7886348B2 (enExample)
KR (1) KR20240000574A (enExample)
CN (1) CN117295726A (enExample)
AR (1) AR125401A1 (enExample)
AU (1) AU2022260537A1 (enExample)
CA (1) CA3215260A1 (enExample)
CL (1) CL2023003154A1 (enExample)
CO (1) CO2023014721A2 (enExample)
CR (1) CR20230496A (enExample)
IL (1) IL306126A (enExample)
MX (1) MX2023012477A (enExample)
PE (1) PE20240239A1 (enExample)
TW (1) TW202309010A (enExample)
WO (1) WO2022223750A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY210507A (en) 2018-08-13 2025-09-28 Hoffmann La Roche New heterocyclic compounds as monoacylglycerol lipase inhibitors
WO2020104494A1 (en) 2018-11-22 2020-05-28 F. Hoffmann-La Roche Ag New heterocyclic compounds
CN114072405A (zh) 2019-07-03 2022-02-18 豪夫迈·罗氏有限公司 杂环单酰基甘油脂肪酶(magl)抑制剂
KR20220034104A (ko) 2019-07-09 2022-03-17 에프. 호프만-라 로슈 아게 신규 헤테로고리 화합물
IL313987A (en) 2021-12-29 2024-08-01 Psy Therapeutics Inc Inhibiting monoacylglycerol lipase (magl)
WO2023130050A1 (en) * 2021-12-29 2023-07-06 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment and management of pain
US20250170100A1 (en) * 2021-12-29 2025-05-29 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment of anxiety and related conditions
AR128333A1 (es) * 2022-01-25 2024-04-17 Hoffmann La Roche Nuevos compuestos heterociclicos
WO2023247670A1 (en) * 2022-06-24 2023-12-28 F. Hoffmann-La Roche Ag New heterocyclic-carbonyl-cyclic compounds as magl inhibitors
AU2023320565A1 (en) 2022-08-05 2025-01-23 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2024215863A2 (en) * 2023-04-13 2024-10-17 Psy Therapeutics, Inc. Inhibiting monoacylglycerol lipase (magl)
WO2025010392A2 (en) * 2023-07-06 2025-01-09 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment of neurological disorders
WO2025010394A2 (en) * 2023-07-06 2025-01-09 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment and management of inflammatory conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20170118A (es) * 2014-10-08 2017-07-10 Hoffmann La Roche Derivados espirodiamina como inhibidores de la aldosterona sintasa
MD3316969T2 (ro) * 2015-07-02 2022-07-31 Janssen Sciences Ireland Unlimited Co Compuși antibacterieni
SG11202001498QA (en) * 2017-09-05 2020-03-30 Blackthorn Therapeutics Inc Vasopressin receptor antagonists and products and methods related thereto
CA3129516A1 (en) * 2018-02-28 2019-09-06 The Trustees Of The University Of Pennsylvania Low affinity poly(ad-ribose) polymerase 1 dependent cytotoxic agents
CN112566636A (zh) * 2018-04-25 2021-03-26 优曼尼蒂治疗公司 化合物及其用途
WO2020104494A1 (en) * 2018-11-22 2020-05-28 F. Hoffmann-La Roche Ag New heterocyclic compounds
CN111793064B (zh) * 2019-04-02 2023-06-23 上海美悦生物科技发展有限公司 一种作为irak抑制剂的化合物及其制备方法和用途
CA3195738A1 (en) * 2020-09-22 2022-03-31 Janssen Pharmaceutica Nv Cyclobutyl amide monoacylglycerol lipase modulators

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