JP2022507828A5 - - Google Patents

Info

Publication number
JP2022507828A5
JP2022507828A5 JP2021527948A JP2021527948A JP2022507828A5 JP 2022507828 A5 JP2022507828 A5 JP 2022507828A5 JP 2021527948 A JP2021527948 A JP 2021527948A JP 2021527948 A JP2021527948 A JP 2021527948A JP 2022507828 A5 JP2022507828 A5 JP 2022507828A5
Authority
JP
Japan
Prior art keywords
cre0058
cre0065
cre0051
cre0066
crm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021527948A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022507828A (ja
JP7489161B2 (ja
Filing date
Publication date
Priority claimed from GBGB1818816.9A external-priority patent/GB201818816D0/en
Application filed filed Critical
Publication of JP2022507828A publication Critical patent/JP2022507828A/ja
Publication of JP2022507828A5 publication Critical patent/JP2022507828A5/ja
Priority to JP2024075266A priority Critical patent/JP7860164B2/ja
Application granted granted Critical
Publication of JP7489161B2 publication Critical patent/JP7489161B2/ja
Priority to JP2026075526A priority patent/JP2026124829A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021527948A 2018-11-19 2019-11-19 肝臓特異的調節性核酸配列 Active JP7489161B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024075266A JP7860164B2 (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列
JP2026075526A JP2026124829A (ja) 2018-11-19 2026-04-28 肝臓特異的調節性核酸配列

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1818816.9A GB201818816D0 (en) 2018-11-19 2018-11-19 Regulatory nucleic acid sequences
GB1818816.9 2018-11-19
PCT/GB2019/053267 WO2020104782A1 (en) 2018-11-19 2019-11-19 Liver-Specific Regulatory Nucleic Acid Sequences

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024075266A Division JP7860164B2 (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列

Publications (3)

Publication Number Publication Date
JP2022507828A JP2022507828A (ja) 2022-01-18
JP2022507828A5 true JP2022507828A5 (enExample) 2022-11-25
JP7489161B2 JP7489161B2 (ja) 2024-05-23

Family

ID=64740036

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021527948A Active JP7489161B2 (ja) 2018-11-19 2019-11-19 肝臓特異的調節性核酸配列
JP2024075266A Active JP7860164B2 (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列
JP2026075526A Pending JP2026124829A (ja) 2018-11-19 2026-04-28 肝臓特異的調節性核酸配列

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024075266A Active JP7860164B2 (ja) 2018-11-19 2024-05-07 肝臓特異的調節性核酸配列
JP2026075526A Pending JP2026124829A (ja) 2018-11-19 2026-04-28 肝臓特異的調節性核酸配列

Country Status (9)

Country Link
US (2) US12590129B2 (enExample)
EP (2) EP3883951A1 (enExample)
JP (3) JP7489161B2 (enExample)
CN (1) CN113454104A (enExample)
AU (2) AU2019382955B2 (enExample)
CA (1) CA3120253A1 (enExample)
GB (1) GB201818816D0 (enExample)
IL (1) IL283219A (enExample)
WO (2) WO2020104783A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021207526A1 (en) 2020-04-09 2021-10-14 The Regents Of The University Of California Humanized notch receptors with hinge domain
KR102726511B1 (ko) 2021-01-20 2024-11-07 주식회사 큐로젠 Ssu72 단백질 또는 Ssu72 단백질을 코딩하는 뉴클레오티드를 포함하는 간암 예방 또는 치료용 약학적 조성물
AU2022214501B2 (en) 2021-01-29 2025-05-22 Curogen Technology Co., Ltd. Pharmaceutical composition for treating liver diseases using ssu72
WO2023008925A1 (ko) * 2021-07-29 2023-02-02 주식회사 리보퓨틱스 융합 프로모터, 이를 포함하는 재조합 벡터 및 이를 이용하는 간암 치료용 조성물
JP2026516710A (ja) * 2023-04-20 2026-05-26 アスクバイオ インコーポレイテッド 肝臓特異的調節核酸配列
CN116555266B (zh) * 2023-06-09 2024-11-12 呈诺再生医学科技(北京)有限公司 肝脏特异性表达的重组启动子和载体及其在肝脏相关疾病治疗中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5721096A (en) * 1991-01-24 1998-02-24 Children's Medical Center Corporation Methods of screening for compounds with ability to alter apolipoprotein AI gene expression
US5578444A (en) 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
US6268212B1 (en) 1993-10-18 2001-07-31 Amgen Inc. Tissue specific transgene expression
EP0933997A4 (en) 1996-09-06 2000-08-16 Chiron Corp METHODS AND COMPOSITIONS FOR LIVER-SPECIFIC ADMINISTRATION OF THERAPEUTIC MOLECULES USING RECOMBINANT AAV VECTORS
US7351813B2 (en) 2000-06-20 2008-04-01 The Board Of Trustees Of The Leland Stanford Junior University Liver-specific gene expression cassettes, and methods of use
WO2002092134A1 (en) 2001-05-14 2002-11-21 Cell Genesys, Inc. Lentiviral vectors encoding clotting factors for gene therapy
CN102634515B (zh) 2008-02-14 2013-11-06 财团法人牧岩生命工学研究所 适于表达用于基因治疗的编码序列的表达载体
CN102628041B (zh) 2008-02-14 2013-09-11 财团法人牧岩生命工学研究所 适于表达用于基因治疗的编码序列的表达载体
US9617548B2 (en) 2008-04-22 2017-04-11 Vib Vzw Liver-specific nucleic acid regulatory elements and methods and use thereof
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
EP2479278A1 (en) 2011-01-25 2012-07-25 Synpromics Ltd. Method for the construction of specific promoters
JP6879486B2 (ja) * 2015-03-17 2021-06-02 フリーイェ・ユニヴェルシテイト・ブリュッセルVrije Universieit Brussel Fviiiおよびfix用の最適化された肝臓特異的発現系
PE20181922A1 (es) 2016-04-15 2018-12-11 Univ Pennsylvania Terapia genica para tratar la hemofilia a
WO2018144709A2 (en) 2017-02-01 2018-08-09 The Trustees Of The University Of Pennsylvania Gene therapy for treating citrullenemia
BR112019024608A2 (pt) 2017-05-24 2020-06-23 Universitat Autonoma De Barcelona Construto de expressão viral que compreende uma sequência de codificação do fator de crescimento de fibroblastos 21 (fgf21)
JP2020533971A (ja) 2017-08-28 2020-11-26 アルター・バイオサイエンス・コーポレーション Il−15をベースとするil−7及びil−21への融合物
CN108588097B (zh) 2018-04-28 2021-07-13 北京锦篮基因科技有限公司 改造后的hbv基因组和相关组合物及其应用

Similar Documents

Publication Publication Date Title
Bridgen et al. Rescue of a segmented negative-strand RNA virus entirely from cloned complementary DNAs
Carelli et al. Mitochondria: biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations
Casas-Mollano et al. CRISPR-Cas activators for engineering gene expression in higher eukaryotes
Wagner Gene duplications, robustness and evolutionary innovations
JP2021526858A5 (enExample)
Yang et al. The evo‐devo of molluscs: insights from a genomic perspective
Kim et al. Effects of NV gene knock-out recombinant viral hemorrhagic septicemia virus (VHSV) on Mx gene expression in Epithelioma papulosum cyprini (EPC) cells and olive flounder (Paralichthys olivaceus)
JP2023509118A5 (enExample)
AR041752A1 (es) Promotores sinteticos que inducen una actividad transcripcional aumentada en celulas cardiacas
JP2021522858A5 (enExample)
JP2006526394A5 (enExample)
JP2022535412A5 (enExample)
JP2019528793A5 (enExample)
Katano et al. Cardiac septation in heart development and evolution
JPS6156200A (ja) 修飾インタ−フエロン
Grisorio et al. Gene therapy for cardiac diseases: methods, challenges, and future directions
Zhang et al. The activation of antiviral RNA interference not only exists in neural progenitor cells but also in somatic cells in mammals
JP2023118937A5 (enExample)
JP2024513907A5 (enExample)
Weasner et al. Retinal expression of the Drosophila eyes absent gene is controlled by several cooperatively acting cis-regulatory elements
JP2022533813A5 (enExample)
Jane et al. Understanding fetal globin gene expression: a step towards effective HbF reactivation in haemoglobinopathies.
Jeffery Evolution of ascidian development
Niculescu Cancer exploits a late premetazoan gene module conserved in the human genome
CN107287216B (zh) CvBV5-3基因在降低果蝇免疫力和制备免疫低下型果蝇模型中的应用