JP2023118937A5 - - Google Patents
Info
- Publication number
- JP2023118937A5 JP2023118937A5 JP2023111541A JP2023111541A JP2023118937A5 JP 2023118937 A5 JP2023118937 A5 JP 2023118937A5 JP 2023111541 A JP2023111541 A JP 2023111541A JP 2023111541 A JP2023111541 A JP 2023111541A JP 2023118937 A5 JP2023118937 A5 JP 2023118937A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- upr
- expression construct
- synthetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1713545.0 | 2017-08-23 | ||
| GBGB1713545.0A GB201713545D0 (en) | 2017-08-23 | 2017-08-23 | Expression control using a regulatable intron |
| PCT/GB2018/052387 WO2019038544A1 (en) | 2017-08-23 | 2018-08-22 | EXPRESSION CONTROL USING AN ADJUSTABLE INTRON |
| JP2020531824A JP7830029B2 (ja) | 2017-08-23 | 2018-08-22 | 制御可能なイントロンを用いる発現調節 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531824A Division JP7830029B2 (ja) | 2017-08-23 | 2018-08-22 | 制御可能なイントロンを用いる発現調節 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023118937A JP2023118937A (ja) | 2023-08-25 |
| JP2023118937A5 true JP2023118937A5 (enExample) | 2026-05-18 |
Family
ID=59996625
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531824A Active JP7830029B2 (ja) | 2017-08-23 | 2018-08-22 | 制御可能なイントロンを用いる発現調節 |
| JP2023111541A Pending JP2023118937A (ja) | 2017-08-23 | 2023-07-06 | 制御可能なイントロンを用いる発現調節 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531824A Active JP7830029B2 (ja) | 2017-08-23 | 2018-08-22 | 制御可能なイントロンを用いる発現調節 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11492618B2 (enExample) |
| EP (1) | EP3673068A1 (enExample) |
| JP (2) | JP7830029B2 (enExample) |
| CN (2) | CN111566216B (enExample) |
| AU (2) | AU2018319637B2 (enExample) |
| GB (1) | GB201713545D0 (enExample) |
| IL (2) | IL314845A (enExample) |
| WO (1) | WO2019038544A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3171636A1 (en) * | 2020-03-26 | 2021-09-30 | Graham WHYTESIDE | Forskolin-inducible promoters and hypoxia-inducible promoters |
| US20230407327A1 (en) * | 2020-03-26 | 2023-12-21 | Asklepios Biopharmaceutical, Inc. | Inducible promoter for viral vector production |
| WO2021209743A1 (en) * | 2020-04-15 | 2021-10-21 | Synpromics Limited | Forskolin-inducible promoters and hypoxia-inducible promoters |
| JP7898267B2 (ja) * | 2021-10-20 | 2026-07-31 | リファインホールディングス株式会社 | 小胞体ストレス抑制剤、神経変性疾患予防改善剤および認知症の予防・進行防止・改善剤、並びに食品 |
| WO2025024776A2 (en) * | 2023-07-27 | 2025-01-30 | Duke University | Compositions comprising xbp1 fragments and methods of use in gene therapy |
| WO2026015884A1 (en) * | 2024-07-11 | 2026-01-15 | Helix Nanotechnologies Inc | Compositions comprising ire-1 binding sequences and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| JP4446057B2 (ja) * | 2002-08-28 | 2010-04-07 | 独立行政法人理化学研究所 | 生体刺激存在下でのｍＲＮＡのフレームシフトを利用した蛋白質の発現方法 |
| AU2003268356A1 (en) * | 2002-08-30 | 2004-03-19 | President And Fellows Of Harvard College | Methods and compositions for modulating xbp-1 activity |
| US20070111258A1 (en) * | 2005-06-22 | 2007-05-17 | Kaufman Randal J | Compositions and methods for modulating the acute phase response |
| US8227184B2 (en) * | 2008-01-14 | 2012-07-24 | President And Fellows Of Harvard College | Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity |
| WO2010151827A1 (en) * | 2009-06-25 | 2010-12-29 | Bayer Healthcare Llc | X-box binding proteins (xbp-1) variants and methods of using the same |
| US20200393447A1 (en) * | 2017-07-09 | 2020-12-17 | Thomas Hughes | Biosensors for measuring cell signaling in stressed and healthy cells |
| WO2021195491A2 (en) * | 2020-03-26 | 2021-09-30 | Asklepios Biopharmaceutical, Inc. | Inducible promoter for viral vector production |
-
2017
- 2017-08-23 GB GBGB1713545.0A patent/GB201713545D0/en not_active Ceased
-
2018
- 2018-08-22 US US16/640,434 patent/US11492618B2/en active Active
- 2018-08-22 WO PCT/GB2018/052387 patent/WO2019038544A1/en not_active Ceased
- 2018-08-22 AU AU2018319637A patent/AU2018319637B2/en active Active
- 2018-08-22 IL IL314845A patent/IL314845A/en unknown
- 2018-08-22 JP JP2020531824A patent/JP7830029B2/ja active Active
- 2018-08-22 CN CN201880068443.0A patent/CN111566216B/zh active Active
- 2018-08-22 CN CN202410738295.6A patent/CN118562839A/zh active Pending
- 2018-08-22 IL IL272800A patent/IL272800B2/en unknown
- 2018-08-22 EP EP18762597.5A patent/EP3673068A1/en active Pending
-
2022
- 2022-11-04 US US17/981,146 patent/US12600969B2/en active Active
-
2023
- 2023-07-06 JP JP2023111541A patent/JP2023118937A/ja active Pending
-
2025
- 2025-07-10 AU AU2025205352A patent/AU2025205352A1/en active Pending
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