JP2020533019A5 - - Google Patents

Download PDF

Info

Publication number
JP2020533019A5
JP2020533019A5 JP2020531824A JP2020531824A JP2020533019A5 JP 2020533019 A5 JP2020533019 A5 JP 2020533019A5 JP 2020531824 A JP2020531824 A JP 2020531824A JP 2020531824 A JP2020531824 A JP 2020531824A JP 2020533019 A5 JP2020533019 A5 JP 2020533019A5
Authority
JP
Japan
Prior art keywords
sequence
nucleic acid
seq
cng
upr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020531824A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020533019A (ja
JP7830029B2 (ja
Filing date
Publication date
Priority claimed from GBGB1713545.0A external-priority patent/GB201713545D0/en
Application filed filed Critical
Publication of JP2020533019A publication Critical patent/JP2020533019A/ja
Publication of JP2020533019A5 publication Critical patent/JP2020533019A5/ja
Priority to JP2023111541A priority Critical patent/JP2023118937A/ja
Application granted granted Critical
Publication of JP7830029B2 publication Critical patent/JP7830029B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020531824A 2017-08-23 2018-08-22 制御可能なイントロンを用いる発現調節 Active JP7830029B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023111541A JP2023118937A (ja) 2017-08-23 2023-07-06 制御可能なイントロンを用いる発現調節

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1713545.0 2017-08-23
GBGB1713545.0A GB201713545D0 (en) 2017-08-23 2017-08-23 Expression control using a regulatable intron
PCT/GB2018/052387 WO2019038544A1 (en) 2017-08-23 2018-08-22 EXPRESSION CONTROL USING AN ADJUSTABLE INTRON

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023111541A Division JP2023118937A (ja) 2017-08-23 2023-07-06 制御可能なイントロンを用いる発現調節

Publications (3)

Publication Number Publication Date
JP2020533019A JP2020533019A (ja) 2020-11-19
JP2020533019A5 true JP2020533019A5 (enExample) 2021-09-24
JP7830029B2 JP7830029B2 (ja) 2026-03-16

Family

ID=59996625

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020531824A Active JP7830029B2 (ja) 2017-08-23 2018-08-22 制御可能なイントロンを用いる発現調節
JP2023111541A Pending JP2023118937A (ja) 2017-08-23 2023-07-06 制御可能なイントロンを用いる発現調節

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023111541A Pending JP2023118937A (ja) 2017-08-23 2023-07-06 制御可能なイントロンを用いる発現調節

Country Status (8)

Country Link
US (2) US11492618B2 (enExample)
EP (1) EP3673068A1 (enExample)
JP (2) JP7830029B2 (enExample)
CN (2) CN111566216B (enExample)
AU (2) AU2018319637B2 (enExample)
GB (1) GB201713545D0 (enExample)
IL (2) IL314845A (enExample)
WO (1) WO2019038544A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3171636A1 (en) * 2020-03-26 2021-09-30 Graham WHYTESIDE Forskolin-inducible promoters and hypoxia-inducible promoters
US20230407327A1 (en) * 2020-03-26 2023-12-21 Asklepios Biopharmaceutical, Inc. Inducible promoter for viral vector production
WO2021209743A1 (en) * 2020-04-15 2021-10-21 Synpromics Limited Forskolin-inducible promoters and hypoxia-inducible promoters
JP7898267B2 (ja) * 2021-10-20 2026-07-31 リファインホールディングス株式会社 小胞体ストレス抑制剤、神経変性疾患予防改善剤および認知症の予防・進行防止・改善剤、並びに食品
WO2025024776A2 (en) * 2023-07-27 2025-01-30 Duke University Compositions comprising xbp1 fragments and methods of use in gene therapy
WO2026015884A1 (en) * 2024-07-11 2026-01-15 Helix Nanotechnologies Inc Compositions comprising ire-1 binding sequences and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
JP4446057B2 (ja) * 2002-08-28 2010-04-07 独立行政法人理化学研究所 生体刺激存在下でのｍＲＮＡのフレームシフトを利用した蛋白質の発現方法
AU2003268356A1 (en) * 2002-08-30 2004-03-19 President And Fellows Of Harvard College Methods and compositions for modulating xbp-1 activity
US20070111258A1 (en) * 2005-06-22 2007-05-17 Kaufman Randal J Compositions and methods for modulating the acute phase response
US8227184B2 (en) * 2008-01-14 2012-07-24 President And Fellows Of Harvard College Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity
WO2010151827A1 (en) * 2009-06-25 2010-12-29 Bayer Healthcare Llc X-box binding proteins (xbp-1) variants and methods of using the same
US20200393447A1 (en) * 2017-07-09 2020-12-17 Thomas Hughes Biosensors for measuring cell signaling in stressed and healthy cells
WO2021195491A2 (en) * 2020-03-26 2021-09-30 Asklepios Biopharmaceutical, Inc. Inducible promoter for viral vector production

Similar Documents

Publication Publication Date Title
JP2023118937A5 (enExample)
IL272800B1 (en) Expression control using a regulatable INTRON
Pandey et al. LBD 18 uses a dual mode of a positive feedback loop to regulate ARF expression and transcriptional activity in Arabidopsis
JP2024102277A (ja) 亢進したｄｎａ産生を有する修飾型細菌レトロエレメント
Braun Temporal translational regulation of the protamine 1 gene during mouse spermatogenesis
Kajihara et al. Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter
HU230368B1 (hu) Új módszer az emlős mesterséges kromoszóma több génnel való feltöltésére
US6867036B1 (en) Gene expression by positive feedback activation of a cell type-specific promoter
Negi et al. Xylem specific activation of 5’upstream regulatory region of two NAC transcription factors (MusaVND6 and MusaVND7) in banana is regulated by SNBE-like sites
Wood et al. Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor.
WO2005054463A1 (ja) レトロトランスポゾンを用いた哺乳動物のゲノム改変技術の開発
CN114891789B (zh) 一种小菜蛾dsRNA的合成方法及其应用
Mink et al. The v-Myb oncoprotein activates C/EBPβ expression by stimulating an autoregulatory loop at the C/EBPβ promoter
Ekström et al. Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E synthase genes is mediated by Sp1 and Sp3
Lau et al. Adaptive evolution of gene expression in Antarctic fishes: divergent transcription of the 5′-to-5′ linked adult α1-and β-globin genes of the Antarctic teleost Notothenia coriiceps is controlled by dual promoters and intergenic enhancers
EP1478750A2 (en) Gene expression by positive feedback activation of a cell type-specific promoter
Aftring et al. Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line, P388D.
US20250215422A1 (en) RT-DNA Fidelity and Retron Genome Editing
JP2002522071A (ja) 真核細胞由来の平均化ｃＤＮＡライブラリーの構築
Christophides et al. Expression and function of the Drosophila melanogaster ADH in male Ceratitis capitata adults: a potential strategy for medfly genetic sexing based on gene‐transfer technology
Zhang et al. The regulation of retina specific expression of rhodopsin gene in vertebrates
Han et al. Cloning and characterization of porcine insulin gene
Ibrahim et al. Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus
Moon et al. Transcriptional regulation of the neuropeptide VGF by the neuron-restrictive silencer factor/neuron-restrictive silencer element
Miura et al. Transfer of spermatogenesis‐related cDNAs into eel testis germ‐somatic cell coculture pellets by electroporation: Methods for analysis of gene function