JP2022507776A5 - - Google Patents

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Publication number
JP2022507776A5
JP2022507776A5 JP2021527829A JP2021527829A JP2022507776A5 JP 2022507776 A5 JP2022507776 A5 JP 2022507776A5 JP 2021527829 A JP2021527829 A JP 2021527829A JP 2021527829 A JP2021527829 A JP 2021527829A JP 2022507776 A5 JP2022507776 A5 JP 2022507776A5
Authority
JP
Japan
Prior art keywords
optionally substituted
alkyl
group
formula
alkylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021527829A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022507776A (ja
JP7551610B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/062030 external-priority patent/WO2020106627A1/en
Publication of JP2022507776A publication Critical patent/JP2022507776A/ja
Publication of JP2022507776A5 publication Critical patent/JP2022507776A5/ja
Priority to JP2024152316A priority Critical patent/JP2025000636A/ja
Application granted granted Critical
Publication of JP7551610B2 publication Critical patent/JP7551610B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021527829A 2018-11-19 2019-11-18 C10-アルキレン置換された13員マクロライド及びそれらの使用 Active JP7551610B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024152316A JP2025000636A (ja) 2018-11-19 2024-09-04 C10-アルキレン置換された13員マクロライド及びそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862769383P 2018-11-19 2018-11-19
US62/769,383 2018-11-19
PCT/US2019/062030 WO2020106627A1 (en) 2018-11-19 2019-11-18 C10-alkylene substituted 13-membered macrolides and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024152316A Division JP2025000636A (ja) 2018-11-19 2024-09-04 C10-アルキレン置換された13員マクロライド及びそれらの使用

Publications (3)

Publication Number Publication Date
JP2022507776A JP2022507776A (ja) 2022-01-18
JP2022507776A5 true JP2022507776A5 (https=) 2022-11-29
JP7551610B2 JP7551610B2 (ja) 2024-09-17

Family

ID=68916562

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021527829A Active JP7551610B2 (ja) 2018-11-19 2019-11-18 C10-アルキレン置換された13員マクロライド及びそれらの使用
JP2024152316A Pending JP2025000636A (ja) 2018-11-19 2024-09-04 C10-アルキレン置換された13員マクロライド及びそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024152316A Pending JP2025000636A (ja) 2018-11-19 2024-09-04 C10-アルキレン置換された13員マクロライド及びそれらの使用

Country Status (19)

Country Link
US (1) US12552825B2 (https=)
EP (2) EP4737470A2 (https=)
JP (2) JP7551610B2 (https=)
KR (1) KR102929869B1 (https=)
CN (1) CN113573779A (https=)
AU (1) AU2019385333B2 (https=)
BR (1) BR112021009624A2 (https=)
CA (1) CA3120148A1 (https=)
DK (1) DK3883647T3 (https=)
ES (1) ES3063764T3 (https=)
FI (1) FI3883647T3 (https=)
IL (1) IL283194B2 (https=)
LT (1) LT3883647T (https=)
MX (1) MX2021005423A (https=)
PT (1) PT3883647T (https=)
SG (1) SG11202105227QA (https=)
SI (1) SI3883647T1 (https=)
SM (1) SMT202600094T1 (https=)
WO (1) WO2020106627A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202313065A (zh) * 2021-05-28 2023-04-01 美商季卡尼醫療公司 用於治療遺傳疾病之化合物
WO2023250513A1 (en) * 2022-06-24 2023-12-28 Zikani Therapeutics, Inc. 13-membered macrolide compounds for treating diseases mediated by abnormal protein translation
CN120152721A (zh) 2022-09-01 2025-06-13 齐卡尼治疗股份有限公司 使用13元大环内酯治疗家族性腺瘤性息肉病

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
NZ526120A (en) * 1999-11-09 2005-02-25 Pfizer Prod Inc 13-membered azalides and their use as antibiotic agents
BR0110382A (pt) * 2000-04-27 2003-06-24 Pfizer Prod Inc Utilização de composições antibióticas azalida para o tratamento ou prevenção de uma infecção causada por bactérias ou protozoários em mamìferos
WO2003014136A1 (en) 2001-08-08 2003-02-20 Taisho Pharmaceutical Co., Ltd. 11a-AZALIDE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
WO2004108744A2 (en) * 2003-05-19 2004-12-16 Prasad K Deshpande Azalides and azaketolides having antimicrobial activity
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
RU2008106915A (ru) * 2005-07-26 2009-09-10 Меркле Гмбх (De) Макролидные конъюгаты пирролиновых и индолизиновых соединений
US8097708B2 (en) * 2006-02-07 2012-01-17 Taisho Pharmaceutical Co., Ltd. 10a-Azalide compound
US20130102551A1 (en) * 2010-07-01 2013-04-25 Andreas Hotte Antibiotic compositions
WO2013004116A1 (zh) * 2011-07-06 2013-01-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
CN106998685A (zh) 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
EP3273969A4 (en) * 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
WO2016154533A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Synthesis of desosamines
US20180273573A1 (en) * 2015-10-01 2018-09-27 Memorial Sloan-Kettering Cancer Center Inhibitors of menaquinone biosynthesis
WO2018201076A2 (en) 2017-04-28 2018-11-01 Macrolide Pharmaceuticals Inc. Macrolides with modified desosamine sugars and uses thereof

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