JP2022507528A - 皮下投与のための医薬製剤 - Google Patents

皮下投与のための医薬製剤 Download PDF

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Publication number
JP2022507528A
JP2022507528A JP2021526553A JP2021526553A JP2022507528A JP 2022507528 A JP2022507528 A JP 2022507528A JP 2021526553 A JP2021526553 A JP 2021526553A JP 2021526553 A JP2021526553 A JP 2021526553A JP 2022507528 A JP2022507528 A JP 2022507528A
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JP
Japan
Prior art keywords
pharmaceutical composition
levodopa
carbidopa
stable liquid
liquid aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021526553A
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English (en)
Japanese (ja)
Other versions
JP2022507528A5 (cg-RX-API-DMAC10.html
Inventor
ムーサ，エハブ
ローズブロー，マシュー
ジャミール，フェロズ
セバー，ナンシー
ファケリス，マウリツィオ・エフ
ロビーソン，ワイニング・ゼット
ロック，チャールズ・エス
シュトットマン，スベン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Inc
Original Assignee
AbbVie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AbbVie Inc filed Critical AbbVie Inc
Publication of JP2022507528A publication Critical patent/JP2022507528A/ja
Publication of JP2022507528A5 publication Critical patent/JP2022507528A5/ja
Priority to JP2024140691A priority Critical patent/JP2024174894A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021526553A 2018-11-15 2019-11-15 皮下投与のための医薬製剤 Pending JP2022507528A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024140691A JP2024174894A (ja) 2018-11-15 2024-08-22 皮下投与のための医薬製剤

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201862767546P 2018-11-15 2018-11-15
US62/767,546 2018-11-15
US201962843945P 2019-05-06 2019-05-06
US62/843,945 2019-05-06
US201962863101P 2019-06-18 2019-06-18
US201962863093P 2019-06-18 2019-06-18
US201962863113P 2019-06-18 2019-06-18
US62/863,113 2019-06-18
US62/863,093 2019-06-18
US62/863,101 2019-06-18
US201962898214P 2019-09-10 2019-09-10
US62/898,214 2019-09-10
PCT/US2019/061626 WO2020102628A1 (en) 2018-11-15 2019-11-15 Pharmaceutical formulations for subcutaneous administration

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024140691A Division JP2024174894A (ja) 2018-11-15 2024-08-22 皮下投与のための医薬製剤

Publications (2)

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JP2022507528A true JP2022507528A (ja) 2022-01-18
JP2022507528A5 JP2022507528A5 (cg-RX-API-DMAC10.html) 2022-11-29

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JP2021526553A Pending JP2022507528A (ja) 2018-11-15 2019-11-15 皮下投与のための医薬製剤
JP2024140691A Pending JP2024174894A (ja) 2018-11-15 2024-08-22 皮下投与のための医薬製剤

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US (3) US12251365B2 (cg-RX-API-DMAC10.html)
EP (1) EP3880210A1 (cg-RX-API-DMAC10.html)
JP (2) JP2022507528A (cg-RX-API-DMAC10.html)
KR (1) KR20210091139A (cg-RX-API-DMAC10.html)
CN (1) CN113015531A (cg-RX-API-DMAC10.html)
AU (2) AU2019379806B2 (cg-RX-API-DMAC10.html)
BR (1) BR112021009353A2 (cg-RX-API-DMAC10.html)
CA (1) CA3117983A1 (cg-RX-API-DMAC10.html)
IL (1) IL282842B1 (cg-RX-API-DMAC10.html)
MX (1) MX2021005776A (cg-RX-API-DMAC10.html)
SG (1) SG11202104499RA (cg-RX-API-DMAC10.html)
TW (1) TW202031265A (cg-RX-API-DMAC10.html)
UY (2) UY41159A (cg-RX-API-DMAC10.html)
WO (1) WO2020102628A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202031265A (zh) 2018-11-15 2020-09-01 美商艾伯維有限公司 用於皮下投藥之醫藥調配物
US20240100072A1 (en) * 2021-10-27 2024-03-28 Abbvie Inc. Subcutaneously administered treatments for advanced parkinson's disease

Citations (1)

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EP3880210A1 (en) 2021-09-22
JP2024174894A (ja) 2024-12-17
MX2021005776A (es) 2021-07-02
UY41159A (es) 2025-09-30
US20250186382A1 (en) 2025-06-12
KR20210091139A (ko) 2021-07-21
IL282842A (en) 2021-06-30
US20250325507A1 (en) 2025-10-23
WO2020102628A1 (en) 2020-05-22
IL282842B1 (en) 2026-08-01
CA3117983A1 (en) 2020-05-22
UY38473A (es) 2020-06-30
AU2019379806A1 (en) 2021-05-27
US12251365B2 (en) 2025-03-18
CN113015531A (zh) 2021-06-22
US20200155578A1 (en) 2020-05-21
AU2025256148A1 (en) 2025-11-13
BR112021009353A2 (pt) 2021-11-23
SG11202104499RA (en) 2021-05-28
AU2019379806B2 (en) 2025-08-14
TW202031265A (zh) 2020-09-01

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