JP2022505663A5 - - Google Patents

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Publication number
JP2022505663A5
JP2022505663A5 JP2021522078A JP2021522078A JP2022505663A5 JP 2022505663 A5 JP2022505663 A5 JP 2022505663A5 JP 2021522078 A JP2021522078 A JP 2021522078A JP 2021522078 A JP2021522078 A JP 2021522078A JP 2022505663 A5 JP2022505663 A5 JP 2022505663A5
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JP
Japan
Prior art keywords
binding
fragment
domain
receptor
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021522078A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022505663A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/057702 external-priority patent/WO2020086745A1/en
Publication of JP2022505663A publication Critical patent/JP2022505663A/ja
Publication of JP2022505663A5 publication Critical patent/JP2022505663A5/ja
Pending legal-status Critical Current

Links

JP2021522078A 2018-10-23 2019-10-23 IgM-Fcベース及びIgA-Fcベースの多価結合分子 Pending JP2022505663A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862749429P 2018-10-23 2018-10-23
US62/749,429 2018-10-23
PCT/US2019/057702 WO2020086745A1 (en) 2018-10-23 2019-10-23 MULTIVALENT IgM- AND IgA-Fc-BASED BINDING MOLECULES

Publications (2)

Publication Number Publication Date
JP2022505663A JP2022505663A (ja) 2022-01-14
JP2022505663A5 true JP2022505663A5 (enExample) 2022-10-28

Family

ID=70331240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021522078A Pending JP2022505663A (ja) 2018-10-23 2019-10-23 IgM-Fcベース及びIgA-Fcベースの多価結合分子

Country Status (11)

Country Link
US (1) US20210380701A1 (enExample)
EP (1) EP3870223A4 (enExample)
JP (1) JP2022505663A (enExample)
KR (1) KR20210083260A (enExample)
CN (1) CN112839677A (enExample)
AU (1) AU2019368289A1 (enExample)
CA (1) CA3113268A1 (enExample)
IL (1) IL281901A (enExample)
MX (1) MX2021004660A (enExample)
SG (1) SG11202103720XA (enExample)
WO (1) WO2020086745A1 (enExample)

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EP3105250B1 (en) 2014-02-10 2020-08-05 IGM Biosciences, Inc. Iga multi-specific binding molecules
PL3560954T3 (pl) 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
IL308212A (en) 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
EP3957738A1 (en) 2015-03-04 2022-02-23 IGM Biosciences, Inc. Cd20 binding molecules and uses thereof
WO2016154593A1 (en) 2015-03-25 2016-09-29 Igm Biosciences, Inc. Multi-valent hepatitis b virus antigen binding molecules and uses thereof
CN107847591B (zh) 2015-04-17 2023-07-28 Igm生物科学股份有限公司 多价人免疫缺陷病毒抗原结合分子及其应用
EP3355913B1 (en) 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
SG11201809336QA (en) 2016-05-09 2018-11-29 Igm Biosciences Inc Anti-pd-l1 antibodies
MX2019011986A (es) 2017-04-07 2019-11-07 Igm Biosciences Inc Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas.
MX2020009069A (es) * 2018-03-01 2020-10-08 Igm Biosciences Inc Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero.
JP2022544405A (ja) 2019-08-15 2022-10-18 アイジーエム バイオサイエンシズ インコーポレイテッド 免疫刺激性多量体型結合分子
US11857620B2 (en) 2020-03-11 2024-01-02 Immunitybio, Inc. Method of inducing immunity against SARS-CoV-2 using spike (s) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus
US12285480B2 (en) 2020-03-11 2025-04-29 Nantcell, Inc. Method of inducing immunity against SARS-CoV-2 using spike and nucleocapsid-ETSD immunogens delivered by RNA and replication-defective adenoviruses
US20210284716A1 (en) 2020-03-11 2021-09-16 Immunitybio, Inc. ACE2-Fc Trap
EP4139362A2 (en) * 2020-04-22 2023-03-01 IGM Biosciences Inc. Pd-1 agonist multimeric binding molecules
CN116813759B (zh) * 2022-03-21 2025-11-28 中国科学院微生物研究所 纳米抗体r14的构建体及其应用
US20250326844A1 (en) * 2022-04-07 2025-10-23 Repertoire Immune Medicines, Inc. T cell receptor multimers and uses thereof
AU2023253516A1 (en) * 2022-04-15 2024-11-21 Imbiologics Corp. Fusion protein platform with improved half-life
WO2024073700A2 (en) * 2022-09-30 2024-04-04 Igm Biosciences, Inc. Methods of treating autoimmune disorders using multimeric anti-cd20/anti-cd3 antibodies

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2257861A1 (en) * 1996-06-14 1997-12-18 Smithkline Beecham Corporation Hexameric fusion proteins and uses therefor
ES2538122T3 (es) * 2008-07-21 2015-06-17 Apogenix Gmbh Moléculas de una sola cadena de TNFSF
EP2760891B1 (en) * 2011-09-26 2018-11-07 JN Biosciences LLC Hybrid constant regions
EP3105250B1 (en) * 2014-02-10 2020-08-05 IGM Biosciences, Inc. Iga multi-specific binding molecules
IL308212A (en) * 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
EP3957738A1 (en) * 2015-03-04 2022-02-23 IGM Biosciences, Inc. Cd20 binding molecules and uses thereof
WO2016154593A1 (en) * 2015-03-25 2016-09-29 Igm Biosciences, Inc. Multi-valent hepatitis b virus antigen binding molecules and uses thereof
JP2019530640A (ja) * 2016-07-20 2019-10-24 アイジーエム バイオサイエンシズ インコーポレイテッド 多量体ox40結合分子及びその使用
MX2019000799A (es) * 2016-07-20 2019-06-03 Igm Biosciences Inc Moleculas de union a gitr multimericas y usos de las mismas.
MX2019011986A (es) * 2017-04-07 2019-11-07 Igm Biosciences Inc Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas.

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