JP2025527694A5 - - Google Patents

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Publication number
JP2025527694A5
JP2025527694A5 JP2025511613A JP2025511613A JP2025527694A5 JP 2025527694 A5 JP2025527694 A5 JP 2025527694A5 JP 2025511613 A JP2025511613 A JP 2025511613A JP 2025511613 A JP2025511613 A JP 2025511613A JP 2025527694 A5 JP2025527694 A5 JP 2025527694A5
Authority
JP
Japan
Prior art keywords
antibody
protein
protein complex
invariant region
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025511613A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025527694A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2023/012348 external-priority patent/WO2024043643A1/ko
Publication of JP2025527694A publication Critical patent/JP2025527694A/ja
Publication of JP2025527694A5 publication Critical patent/JP2025527694A5/ja
Pending legal-status Critical Current

Links

JP2025511613A 2022-08-23 2023-08-21 Il2変異体及びそれを含むタンパク質複合体 Pending JP2025527694A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20220105643 2022-08-23
KR10-2022-0105643 2022-08-23
KR20230057361 2023-05-02
KR10-2023-0057361 2023-05-02
PCT/KR2023/012348 WO2024043643A1 (ko) 2022-08-23 2023-08-21 Il2 변이체 및 이를 포함하는 단백질 복합체

Publications (2)

Publication Number Publication Date
JP2025527694A JP2025527694A (ja) 2025-08-22
JP2025527694A5 true JP2025527694A5 (enExample) 2025-09-19

Family

ID=90013668

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025511613A Pending JP2025527694A (ja) 2022-08-23 2023-08-21 Il2変異体及びそれを含むタンパク質複合体

Country Status (6)

Country Link
EP (1) EP4578871A1 (enExample)
JP (1) JP2025527694A (enExample)
KR (1) KR102655850B1 (enExample)
CN (1) CN119790064A (enExample)
AU (1) AU2023330441A1 (enExample)
WO (1) WO2024043643A1 (enExample)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060234205A1 (en) * 2004-03-05 2006-10-19 Chiron Corporation In vitro test system for predicting patient tolerability of therapeutic agents
AU2013258834B2 (en) * 2012-05-10 2017-09-07 Zymeworks Bc Inc. Heteromultimer constructs of immunoglobulin heavy chains with mutations in the Fc domain
DK3186283T3 (da) * 2014-08-29 2020-03-02 Hoffmann La Roche Kombinationsbehandling med tumormålrettede IL-2- immuncytokinervarianter og antistoffer mod humant PD-L1
AU2017213659B2 (en) * 2016-02-05 2024-04-18 Washington University Compositions and methods for targeted cytokine delivery
AU2017335771A1 (en) * 2016-09-28 2019-02-28 Musc Foundation For Research Development Antibodies that bind interleukin-2 and uses thereof
EP3504234A4 (en) * 2016-09-29 2020-12-02 Beijing Hanmi Pharmaceutical Co., Ltd. CONSTRUCTIONS OF HETERODIMERIC IMMUNOGLOBULINS AND THEIR PREPARATION PROCESSES
CU24483B1 (es) * 2016-11-15 2020-04-02 Ct Inmunologia Molecular Método para incrementar los niveles de secreción de la interleucina-2
MY201482A (en) * 2017-04-03 2024-02-26 Hoffmann La Roche Immunoconjugates of an anti-pd-1 antibody with a mutant il-2 or with il-15
IL275426B2 (en) * 2017-12-19 2025-03-01 Xencor Inc Engineered il-2 fc fusion proteins
CA3098930A1 (en) * 2018-09-21 2020-03-26 Innovent Biologics (Suzhou) Co., Ltd. Novel interleukin-2 and use thereof
JP2022554141A (ja) 2019-10-25 2022-12-28 オーデンツ セラピューティクス,インコーポレーテッド 糖原病を治療するための組成物及び方法
KR102559355B1 (ko) * 2020-01-31 2023-07-25 주식회사 제넥신 항-taa 항체, 항-pd-l1 항체 및 il-2를 포함하는 융합단백질 및 이의 용도
CN118271419A (zh) * 2020-03-31 2024-07-02 韩美药品株式会社 新型免疫刺激il-2类似物
US20240034854A1 (en) 2020-08-26 2024-02-01 Reventas Limited Improvements In Or Relating To Plastic Recycling

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