JP2025527694A5 - - Google Patents

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Publication number
JP2025527694A5
JP2025527694A5 JP2025511613A JP2025511613A JP2025527694A5 JP 2025527694 A5 JP2025527694 A5 JP 2025527694A5 JP 2025511613 A JP2025511613 A JP 2025511613A JP 2025511613 A JP2025511613 A JP 2025511613A JP 2025527694 A5 JP2025527694 A5 JP 2025527694A5
Authority
JP
Japan
Prior art keywords
antibody
protein
protein complex
invariant region
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025511613A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025527694A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2023/012348 external-priority patent/WO2024043643A1/ko
Publication of JP2025527694A publication Critical patent/JP2025527694A/ja
Publication of JP2025527694A5 publication Critical patent/JP2025527694A5/ja
Pending legal-status Critical Current

Links

JP2025511613A 2022-08-23 2023-08-21 Il2変異体及びそれを含むタンパク質複合体 Pending JP2025527694A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20220105643 2022-08-23
KR10-2022-0105643 2022-08-23
KR20230057361 2023-05-02
KR10-2023-0057361 2023-05-02
PCT/KR2023/012348 WO2024043643A1 (ko) 2022-08-23 2023-08-21 Il2 변이체 및 이를 포함하는 단백질 복합체

Publications (2)

Publication Number Publication Date
JP2025527694A JP2025527694A (ja) 2025-08-22
JP2025527694A5 true JP2025527694A5 (enExample) 2025-09-19

Family

ID=90013668

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025511613A Pending JP2025527694A (ja) 2022-08-23 2023-08-21 Il2変異体及びそれを含むタンパク質複合体

Country Status (6)

Country Link
EP (1) EP4578871A4 (enExample)
JP (1) JP2025527694A (enExample)
KR (1) KR102655850B1 (enExample)
CN (1) CN119790064A (enExample)
AU (1) AU2023330441A1 (enExample)
WO (1) WO2024043643A1 (enExample)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070003934A (ko) * 2004-03-05 2007-01-05 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 치료제의 환자 내약성을 예측하기 위한 시험관 내 테스트시스템
WO2009061853A2 (en) * 2007-11-05 2009-05-14 Massachusetts Institute Of Technology Mutant interleukin-2 (il-2) polypeptides
JP6351572B2 (ja) * 2012-05-10 2018-07-04 ザイムワークス,インコーポレイテッド Fcドメインに突然変異を有する免疫グロブリン重鎖のヘテロ多量体構築物
ES2774380T3 (es) * 2014-08-29 2020-07-20 Hoffmann La Roche Politerapia de inmunocitocinas de variante de IL-2 dirigida a tumor y anticuerpos frente a PD-L1 humano
US11053293B2 (en) * 2016-02-05 2021-07-06 Washington University Compositions and methods for targeted cytokine delivery
US10858428B2 (en) * 2016-09-28 2020-12-08 Xoma (Us) Llc Antibodies that bind interleukin-2 and uses thereof
SG10201913263SA (en) * 2016-09-29 2020-03-30 Beijing Hanmi Pharmaceutical Co Ltd Heterodimeric immunoglobulin constructs and preparation methods thereof
CU24483B1 (es) * 2016-11-15 2020-04-02 Ct Inmunologia Molecular Método para incrementar los niveles de secreción de la interleucina-2
KR102461885B1 (ko) * 2017-04-03 2022-11-03 에프. 호프만-라 로슈 아게 항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
JP7765181B2 (ja) * 2017-12-19 2025-11-06 ゼンコア インコーポレイテッド 改変されたil-2 fc融合タンパク質
CA3098930A1 (en) * 2018-09-21 2020-03-26 Innovent Biologics (Suzhou) Co., Ltd. Novel interleukin-2 and use thereof
AU2020372429A1 (en) 2019-10-25 2022-04-28 Audentes Therapeutics, Inc. Compositions and methods for treating glycogen storage disorders
KR102559355B1 (ko) * 2020-01-31 2023-07-25 주식회사 제넥신 항-taa 항체, 항-pd-l1 항체 및 il-2를 포함하는 융합단백질 및 이의 용도
AR121713A1 (es) * 2020-03-31 2022-06-29 Hanmi Pharm Ind Co Ltd Nuevos análogos de il-2 inmunoestimulantes
US20230295394A1 (en) 2020-08-26 2023-09-21 Reventas Limited Improvements In Or Relating To Plastic Recycling

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