JP2022504712A5 - - Google Patents
Info
- Publication number
- JP2022504712A5 JP2022504712A5 JP2021519846A JP2021519846A JP2022504712A5 JP 2022504712 A5 JP2022504712 A5 JP 2022504712A5 JP 2021519846 A JP2021519846 A JP 2021519846A JP 2021519846 A JP2021519846 A JP 2021519846A JP 2022504712 A5 JP2022504712 A5 JP 2022504712A5
- Authority
- JP
- Japan
- Prior art keywords
- polymerase
- poly
- oligonucleotide
- nucleotide
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862745136P | 2018-10-12 | 2018-10-12 | |
| US62/745,136 | 2018-10-12 | ||
| PCT/US2019/055870 WO2020077227A2 (en) | 2018-10-12 | 2019-10-11 | Enzymatic rna synthesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022504712A JP2022504712A (ja) | 2022-01-13 |
| JP2022504712A5 true JP2022504712A5 (https=) | 2022-10-19 |
| JP7646209B2 JP7646209B2 (ja) | 2025-03-17 |
Family
ID=69232884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021519846A Active JP7646209B2 (ja) | 2018-10-12 | 2019-10-11 | 酵素によるｒｎａ合成 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220145295A1 (https=) |
| EP (1) | EP3864151A2 (https=) |
| JP (1) | JP7646209B2 (https=) |
| KR (2) | KR20260047628A (https=) |
| CN (2) | CN120829942A (https=) |
| WO (1) | WO2020077227A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3826762A1 (en) | 2018-07-23 | 2021-06-02 | DNA Script | Massively parallel enzymatic synthesis of nucleic acid strands |
| WO2020165137A1 (en) | 2019-02-12 | 2020-08-20 | Dna Script | Efficient product cleavage in template-free enzymatic synthesis of polynucleotides. |
| WO2021018919A1 (en) * | 2019-07-30 | 2021-02-04 | Dna Script | Template-free enzymatic synthesis of polynucleotides using poly(a) and poly(u) polymerases |
| WO2022013094A1 (en) | 2020-07-15 | 2022-01-20 | Dna Script | Massively parallel enzymatic synthesis of polynucleotides |
| EP4334330A1 (en) | 2021-05-07 | 2024-03-13 | Helix Nanotechnologies, Inc. | Modified ribonucleic acids and uses thereof |
| CA3234383A1 (en) | 2021-10-15 | 2023-04-27 | Codexis, Inc. | Engineered terminal deoxynucleotidyl transferase variants |
| CN116732020A (zh) * | 2022-03-02 | 2023-09-12 | 中国科学院分子细胞科学卓越创新中心 | 提高rna分子的胞内翻译效率和/或稳定性的方法 |
| US20250207163A1 (en) * | 2022-03-25 | 2025-06-26 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
| EP4630540A1 (en) * | 2022-12-05 | 2025-10-15 | DNA Script | Variants of poly(a) polymerase and uses thereof |
| WO2024141628A1 (en) | 2022-12-31 | 2024-07-04 | Dna Script | Variable viscosity inks for inkjet delivery of enzyme reagents |
| WO2024153643A1 (en) | 2023-01-16 | 2024-07-25 | Dna Script | Inkjet-assisted enzymatic nucleic acid synthesis |
| EP4731762A2 (en) * | 2023-06-21 | 2026-04-29 | Ansa Biotechnologies, Inc. | De novo stepwise template-independent synthesis of long polynucleotides |
| CN118109539A (zh) * | 2024-04-08 | 2024-05-31 | 华南理工大学 | 一种无模板酶法合成含非天然碱基的核糖核酸链的方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2290073A3 (en) * | 2004-05-28 | 2011-08-31 | Asuragen, Inc. | Methods and compositions involving microRNA |
| WO2011038241A1 (en) | 2009-09-25 | 2011-03-31 | President And Fellows Of Harvard College | Nucleic acid amplification and sequencing by synthesis with fluorogenic nucleotides |
| EP2551354A1 (en) * | 2011-07-25 | 2013-01-30 | Universität Heidelberg | Functionalization of RNA oligonucleotides |
| US10683536B2 (en) * | 2013-04-02 | 2020-06-16 | Molecular Assemblies, Inc. | Reusable initiators for synthesizing nucleic acids |
| US9771613B2 (en) * | 2013-04-02 | 2017-09-26 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acid |
-
2019
- 2019-10-11 KR KR1020267008411A patent/KR20260047628A/ko active Pending
- 2019-10-11 CN CN202510727733.3A patent/CN120829942A/zh active Pending
- 2019-10-11 US US17/283,728 patent/US20220145295A1/en active Pending
- 2019-10-11 WO PCT/US2019/055870 patent/WO2020077227A2/en not_active Ceased
- 2019-10-11 CN CN201980082542.9A patent/CN113195720B/zh active Active
- 2019-10-11 JP JP2021519846A patent/JP7646209B2/ja active Active
- 2019-10-11 KR KR1020217014145A patent/KR102942644B1/ko active Active
- 2019-10-11 EP EP19842846.8A patent/EP3864151A2/en active Pending
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