JP2022504153A5 - - Google Patents
Info
- Publication number
- JP2022504153A5 JP2022504153A5 JP2021518432A JP2021518432A JP2022504153A5 JP 2022504153 A5 JP2022504153 A5 JP 2022504153A5 JP 2021518432 A JP2021518432 A JP 2021518432A JP 2021518432 A JP2021518432 A JP 2021518432A JP 2022504153 A5 JP2022504153 A5 JP 2022504153A5
- Authority
- JP
- Japan
- Prior art keywords
- insulin
- egf
- gaqp
- desb30
- gglu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18198892.4 | 2018-10-05 | ||
| EP18198892 | 2018-10-05 | ||
| PCT/EP2019/076889 WO2020070276A1 (en) | 2018-10-05 | 2019-10-04 | Bifunctional compounds comprising insulin peptides and egf(a) peptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022504153A JP2022504153A (ja) | 2022-01-13 |
| JP2022504153A5 true JP2022504153A5 (https=) | 2022-10-12 |
| JP7434299B2 JP7434299B2 (ja) | 2024-02-20 |
Family
ID=64017248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021518432A Active JP7434299B2 (ja) | 2018-10-05 | 2019-10-04 | インスリンペプチドおよびｅｇｆ（ａ）ペプチドを含む二官能性化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11649269B2 (https=) |
| EP (1) | EP3861017A1 (https=) |
| JP (1) | JP7434299B2 (https=) |
| CN (1) | CN112789289A (https=) |
| AR (1) | AR116605A1 (https=) |
| MA (1) | MA53809A (https=) |
| TW (1) | TW202028229A (https=) |
| WO (1) | WO2020070276A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018107117A1 (en) | 2016-12-09 | 2018-06-14 | Akston Biosciences Corporation | Insulin-fc fusions and methods of use |
| KR20210029210A (ko) | 2018-06-29 | 2021-03-15 | 악스톤 바이오사이언시스 코퍼레이션 | 초장기 작용 인슐린-fc 융합 단백질 및 사용 방법 |
| US11267862B2 (en) | 2018-06-29 | 2022-03-08 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
| KR20250142943A (ko) | 2019-12-19 | 2025-09-30 | 악스톤 바이오사이언시스 코퍼레이션 | 초-장기 작용 인슐린-fc 융합 단백질 및 사용 방법 |
| US11186623B2 (en) | 2019-12-24 | 2021-11-30 | Akston Bioscience Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
| US11192930B2 (en) | 2020-04-10 | 2021-12-07 | Askton Bioscences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
| LT3972987T (lt) | 2020-04-10 | 2023-09-25 | Akston Biosciences Corporation | Antigenui specifinė imunoterapija, skirta sulietiems covid-19 baltymams ir naudojimo būdai |
| US11198719B2 (en) | 2020-04-29 | 2021-12-14 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
| CN114729060B (zh) | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| EP4373861A4 (en) | 2021-07-23 | 2025-08-20 | Akston Biosciences Corp | INSULIN-FC FUSION PROTEINS AND METHODS OF USE FOR TREATING CANCER |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| CN115947822B (zh) * | 2022-07-04 | 2023-08-18 | 北京惠之衡生物科技有限公司 | 一种长效酰化胰岛素衍生物及其药物组合物和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5721432B2 (ja) | 2007-08-15 | 2015-05-20 | ノボ・ノルデイスク・エー／エス | アミノ酸含有アルキレングリコール反復単位を含むアシル部を有するインスリン |
| HUE032284T2 (en) | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| MX2010011499A (es) | 2008-04-23 | 2010-11-12 | Amgen Inc | Variantes de proproteina neutralizante de convertasa subtilisina kexina de tipo 9 (pcsk9) y sus usos. |
| GB201005005D0 (en) | 2010-03-25 | 2010-05-12 | Angeletti P Ist Richerche Bio | New vaccine |
| WO2012177741A1 (en) | 2011-06-20 | 2012-12-27 | Genentech, Inc. | Pcsk9-binding polypeptides and methods of use |
| CA2935285A1 (en) | 2014-02-21 | 2015-08-27 | Medimmune, Llc | Anti-pcsk9-glp-1 fusions and methods for use |
| CN104558199B (zh) | 2014-09-05 | 2018-07-06 | 成都康弘生物科技有限公司 | 一种治疗高胆固醇血症的融合蛋白制备及其用途 |
| WO2016164762A1 (en) | 2015-04-08 | 2016-10-13 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same |
| ES2908373T3 (es) | 2015-08-25 | 2022-04-28 | Novo Nordisk As | Nuevos derivados de insulina y los usos médicos de los mismos |
| SI3402811T1 (sl) | 2016-01-13 | 2022-06-30 | Novo Nordisk A/S | Analogi EGF(A) z maščobnokislinskimi substituenti |
-
2019
- 2019-10-04 WO PCT/EP2019/076889 patent/WO2020070276A1/en not_active Ceased
- 2019-10-04 EP EP19783295.9A patent/EP3861017A1/en not_active Withdrawn
- 2019-10-04 US US17/281,813 patent/US11649269B2/en active Active
- 2019-10-04 TW TW108135986A patent/TW202028229A/zh unknown
- 2019-10-04 MA MA053809A patent/MA53809A/fr unknown
- 2019-10-04 JP JP2021518432A patent/JP7434299B2/ja active Active
- 2019-10-04 CN CN201980064514.4A patent/CN112789289A/zh not_active Withdrawn
- 2019-10-04 AR ARP190102838A patent/AR116605A1/es unknown
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