JP2022502476A5 - - Google Patents
Info
- Publication number
- JP2022502476A5 JP2022502476A5 JP2021521024A JP2021521024A JP2022502476A5 JP 2022502476 A5 JP2022502476 A5 JP 2022502476A5 JP 2021521024 A JP2021521024 A JP 2021521024A JP 2021521024 A JP2021521024 A JP 2021521024A JP 2022502476 A5 JP2022502476 A5 JP 2022502476A5
- Authority
- JP
- Japan
- Prior art keywords
- iii
- pharmaceutically acceptable
- ring
- acceptable salt
- viii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862746277P | 2018-10-16 | 2018-10-16 | |
| US62/746,277 | 2018-10-16 | ||
| PCT/US2019/056455 WO2020081636A1 (en) | 2018-10-16 | 2019-10-16 | Indole ahr inhibitors and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022502476A JP2022502476A (ja) | 2022-01-11 |
| JP2022502476A5 true JP2022502476A5 (https=) | 2022-10-25 |
Family
ID=70284697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521024A Pending JP2022502476A (ja) | 2018-10-16 | 2019-10-16 | インドールａｈｒ阻害剤およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220144839A1 (https=) |
| EP (1) | EP3867253A4 (https=) |
| JP (1) | JP2022502476A (https=) |
| KR (1) | KR20210110566A (https=) |
| CN (1) | CN113272305A (https=) |
| AU (1) | AU2019360204A1 (https=) |
| BR (1) | BR112021007017A2 (https=) |
| CA (1) | CA3115711A1 (https=) |
| EA (1) | EA202190726A1 (https=) |
| IL (1) | IL282252A (https=) |
| MX (1) | MX2021004245A (https=) |
| SG (1) | SG11202103796TA (https=) |
| WO (1) | WO2020081636A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019012431A (es) | 2017-04-21 | 2020-08-03 | Ikena Oncology Inc | Inhibidores del receptor de hidrocarburos de arilo (ahr) de indol y usos de los mismos. |
| AU2020394424A1 (en) | 2019-11-26 | 2022-06-16 | Ikena Oncology, Inc. | Polymorphic carbazole derivatives and uses thereof |
| CA3167283A1 (en) | 2020-01-10 | 2021-07-15 | Ikena Oncology, Inc. | Ahr inhibitors and uses thereof |
| US12570638B2 (en) | 2020-05-20 | 2026-03-10 | Sail Biomedicines, Inc. | Fused imidazole derivatives as AHR antagonists |
| KR20230066311A (ko) * | 2020-06-10 | 2023-05-15 | 델릭스 테라퓨틱스, 인크. | 삼환형 사이코플라스토겐 및 이의 용도 |
| CN114369097B (zh) * | 2020-10-15 | 2023-07-14 | 山东轩竹医药科技有限公司 | 杂芳环类AhR抑制剂 |
| MX2023004847A (es) * | 2020-10-28 | 2023-07-11 | Ikena Oncology Inc | Combinación de un inhibidor del receptor de hidrocarburos de arilo (ahr) con un inhibidor de pdx o doxorrubicina. |
| KR20230124583A (ko) | 2020-11-23 | 2023-08-25 | 이난타 파마슈티칼스, 인코포레이티드 | 신규한 스피로피롤리딘 유래 항바이러스제 |
| US12540141B2 (en) | 2020-11-23 | 2026-02-03 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| CN114456178B (zh) * | 2021-01-13 | 2023-06-02 | 北京华森英诺生物科技有限公司 | 四氢嘧啶[1,2-b]吲唑-4-胺类衍生物作为AhR抑制剂的用途及制备方法 |
| CN114805361B (zh) * | 2021-01-17 | 2024-02-20 | 上海凌达生物医药有限公司 | 一类氨基取代的芳香杂环并吡唑类化合物、制备方法和用途 |
| WO2022235605A1 (en) | 2021-05-04 | 2022-11-10 | Enanta Pharmaceuticals, Inc. | Novel macrocyclic antiviral agents |
| US11912714B2 (en) | 2021-11-12 | 2024-02-27 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| US11919910B2 (en) | 2021-11-12 | 2024-03-05 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| US11858945B2 (en) | 2021-11-12 | 2024-01-02 | Enanta Pharmaceuticals, Inc. | Alkyne-containing antiviral agents |
| WO2023107419A1 (en) | 2021-12-08 | 2023-06-15 | Enanta Pharmaceuticals, Inc. | Saturated spirocyclics as antiviral agents |
| WO2023137007A1 (en) * | 2022-01-11 | 2023-07-20 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 4,6,7-trifluoro-1h-indole-2-carboxylic acid |
| WO2023196307A1 (en) | 2022-04-05 | 2023-10-12 | Enanta Pharmaceuticals, Inc. | Novel spiropyrrolidine derived antiviral agents |
| IL315733A (en) | 2022-04-08 | 2024-11-01 | SHY Therapeutics LLC | Compounds that Interact with RAS Superfamily Proteins for the Treatment of Cancer, Inflammatory, Basoplastic, and Fibrotic Diseases |
| CN117624168A (zh) * | 2022-08-19 | 2024-03-01 | 德明药泰生物技术（深圳）有限公司 | 稠环杂环类化合物及其制备方法和应用 |
| JPWO2024101336A1 (https=) | 2022-11-07 | 2024-05-16 | ||
| KR20240169284A (ko) | 2023-05-24 | 2024-12-03 | 경희대학교 산학협력단 | AhR-매개 질환의 예방, 개선 또는 치료용 약학적 조성물 |
| WO2025114771A1 (en) | 2023-11-29 | 2025-06-05 | Latvian Institute Of Organic Synthesis | A new class of aryl hydrocarbon receptor antagonists and their optimisation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5721356A (en) * | 1989-09-15 | 1998-02-24 | Gensia, Inc. | Orally active adenosine kinase inhibitors |
| JP4895806B2 (ja) * | 2003-04-09 | 2012-03-14 | エクセリクシス， インク． | Ｔｉｅ−２モジュレータと使用方法 |
| AR047969A1 (es) * | 2004-02-25 | 2006-03-15 | Schering Corp | Pirazolotriazinas como inhibidores de quinasa |
| PE20100362A1 (es) * | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| CN108290855A (zh) * | 2015-07-01 | 2018-07-17 | 西北大学 | 被取代的喹唑啉化合物及其调节葡糖脑苷脂酶活性的用途 |
| US20180072741A1 (en) * | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| MX2019012431A (es) * | 2017-04-21 | 2020-08-03 | Ikena Oncology Inc | Inhibidores del receptor de hidrocarburos de arilo (ahr) de indol y usos de los mismos. |
-
2019
- 2019-10-16 EP EP19873025.1A patent/EP3867253A4/en not_active Withdrawn
- 2019-10-16 CA CA3115711A patent/CA3115711A1/en active Pending
- 2019-10-16 WO PCT/US2019/056455 patent/WO2020081636A1/en not_active Ceased
- 2019-10-16 MX MX2021004245A patent/MX2021004245A/es unknown
- 2019-10-16 BR BR112021007017-6A patent/BR112021007017A2/pt not_active IP Right Cessation
- 2019-10-16 EA EA202190726A patent/EA202190726A1/ru unknown
- 2019-10-16 JP JP2021521024A patent/JP2022502476A/ja active Pending
- 2019-10-16 SG SG11202103796TA patent/SG11202103796TA/en unknown
- 2019-10-16 AU AU2019360204A patent/AU2019360204A1/en not_active Abandoned
- 2019-10-16 KR KR1020217014753A patent/KR20210110566A/ko not_active Withdrawn
- 2019-10-16 US US17/281,395 patent/US20220144839A1/en not_active Abandoned
- 2019-10-16 CN CN201980076086.7A patent/CN113272305A/zh active Pending
-
2021
- 2021-04-12 IL IL282252A patent/IL282252A/en unknown
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