JP2022141670A5 - - Google Patents

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Publication number
JP2022141670A5
JP2022141670A5 JP2022103103A JP2022103103A JP2022141670A5 JP 2022141670 A5 JP2022141670 A5 JP 2022141670A5 JP 2022103103 A JP2022103103 A JP 2022103103A JP 2022103103 A JP2022103103 A JP 2022103103A JP 2022141670 A5 JP2022141670 A5 JP 2022141670A5
Authority
JP
Japan
Prior art keywords
aav vector
cell
pharmaceutical composition
subject
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022103103A
Other languages
English (en)
Japanese (ja)
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JP2022141670A (ja
Filing date
Publication date
Priority claimed from GBGB1519086.1A external-priority patent/GB201519086D0/en
Application filed filed Critical
Publication of JP2022141670A publication Critical patent/JP2022141670A/ja
Publication of JP2022141670A5 publication Critical patent/JP2022141670A5/ja
Priority to JP2024112812A priority Critical patent/JP2024156706A/ja
Pending legal-status Critical Current

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JP2022103103A 2015-10-28 2022-06-28 遺伝子治療 Pending JP2022141670A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024112812A JP2024156706A (ja) 2015-10-28 2024-07-12 遺伝子治療

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1519086.1 2015-10-28
GBGB1519086.1A GB201519086D0 (en) 2015-10-28 2015-10-28 Gene Therapy
JP2018541571A JP7126944B2 (ja) 2015-10-28 2016-10-27 遺伝子治療
PCT/GB2016/053343 WO2017072515A1 (en) 2015-10-28 2016-10-27 Gene therapy

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018541571A Division JP7126944B2 (ja) 2015-10-28 2016-10-27 遺伝子治療

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024112812A Division JP2024156706A (ja) 2015-10-28 2024-07-12 遺伝子治療

Publications (2)

Publication Number Publication Date
JP2022141670A JP2022141670A (ja) 2022-09-29
JP2022141670A5 true JP2022141670A5 (https=) 2022-10-07

Family

ID=55130363

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018541571A Active JP7126944B2 (ja) 2015-10-28 2016-10-27 遺伝子治療
JP2022103103A Pending JP2022141670A (ja) 2015-10-28 2022-06-28 遺伝子治療
JP2024112812A Pending JP2024156706A (ja) 2015-10-28 2024-07-12 遺伝子治療

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2018541571A Active JP7126944B2 (ja) 2015-10-28 2016-10-27 遺伝子治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024112812A Pending JP2024156706A (ja) 2015-10-28 2024-07-12 遺伝子治療

Country Status (19)

Country Link
US (3) US20190255193A1 (https=)
EP (3) EP3360890B1 (https=)
JP (3) JP7126944B2 (https=)
KR (1) KR102922606B1 (https=)
CN (4) CN117343960A (https=)
AU (3) AU2016344523B2 (https=)
CA (1) CA3002125A1 (https=)
DK (2) DK3262066T4 (https=)
ES (2) ES2828050T3 (https=)
GB (1) GB201519086D0 (https=)
HK (1) HK1248723B (https=)
IL (3) IL304084B2 (https=)
MX (1) MX366343B (https=)
NO (1) NO3262066T3 (https=)
PL (2) PL3360890T3 (https=)
RU (1) RU2740038C2 (https=)
SG (1) SG11201802934WA (https=)
WO (1) WO2017072515A1 (https=)
ZA (1) ZA201802462B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108291216B (zh) 2015-09-24 2022-09-16 宾夕法尼亚州大学信托人 用于治疗补体介导的疾病的组合物和方法
GB201519086D0 (en) * 2015-10-28 2015-12-09 Syncona Partners Llp Gene Therapy
JP7046828B2 (ja) 2016-04-15 2022-04-04 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 滲出型加齢性黄斑変性の治療のための組成物
GB201608046D0 (en) * 2016-05-09 2016-06-22 Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The Treatment of complement-mediated disorders
KR20200036912A (ko) * 2017-07-31 2020-04-07 리플렉션 바이오테크놀러지스 리미티드 안과 질환을 위한 세포 모델 및 치료요법
CN111788311A (zh) * 2017-10-20 2020-10-16 双子治疗公司 用于治疗年龄相关性黄斑变性的组合物和方法
US12558434B2 (en) 2018-02-20 2026-02-24 The Trustees Of The University Of Pennsylvania Compositions for treatment of wet age-related macular degeneration
WO2020077091A1 (en) * 2018-10-10 2020-04-16 Wisconsin Alumni Research Foundation Kir 7.1 gene therapy vectors and methods of using the same
CA3117551A1 (en) * 2018-10-23 2020-04-30 Gemini Therapeutics Inc. Compositions and methods for treating age-related macular degeneration and other diseases
GB201821089D0 (en) * 2018-12-21 2019-02-06 Gyroscope Therapeutics Ltd Codon-optimised complement factor I
GB201821082D0 (en) * 2018-12-21 2019-02-06 Gyroscope Therapeutics Ltd Combination of complement factors i and h, and vector encoding thereof
EP4667578A3 (en) * 2019-04-03 2026-04-01 REGENXBIO Inc. Gene therapy for eye pathologies
EP4028025A4 (en) * 2019-09-09 2023-07-19 University of Pittsburgh - of the Commonwealth System of Higher Education METHODS OF RESTORING LYSOSOMAL FUNCTION OF RETINAL PIGMENT EPITHELIAL CELLS BY TFEB ACTIVATION
AU2021293174A1 (en) 2020-06-14 2023-01-19 Vertex Pharmaceuticals Incorporated Complement Factor I-related compositions and methods
GB202009741D0 (en) 2020-06-25 2020-08-12 Freeline Therapeutics Ltd Polynucleotide
IL301131A (en) * 2020-09-09 2023-05-01 Homology Medicines Inc Vector antibodies and their uses
US20230390296A1 (en) 2020-10-30 2023-12-07 Keio University Novel treatment and prevention of sarcopenia-related diseases
GB202018320D0 (en) * 2020-11-20 2021-01-06 Univ Newcastle Methods of producing recombinant complement proteins
WO2023079301A1 (en) 2021-11-04 2023-05-11 Freeline Therapeutics Limited Assays using mutant complement factor i variants with decreased activity
JPWO2023145735A1 (https=) 2022-01-25 2023-08-03

Family Cites Families (20)

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GB9803351D0 (en) 1998-02-17 1998-04-15 Oxford Biomedica Ltd Anti-viral vectors
US6759237B1 (en) 1998-11-05 2004-07-06 The Trustees Of The University Of Pennsylvania Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
GB0009760D0 (en) 2000-04-19 2000-06-07 Oxford Biomedica Ltd Method
RU2005138368A (ru) * 2003-06-10 2006-07-27 ЭнЭсДЖЕНЕ А/С (DK) Улучшенная секреция нейбластина
EP2357254A1 (en) 2005-02-14 2011-08-17 University of Iowa Research Foundation Methods and reagents for treatment and diagnosis of age-related macular degeneration
EP2433642B1 (en) * 2005-10-21 2016-12-07 Catalyst Biosciences, Inc. Modified proteases that inhibit complement activation
WO2007149567A2 (en) 2006-06-21 2007-12-27 Musc Foundation For Research Development Targeting complement factor h for treatment of diseases
CN101657097A (zh) * 2007-03-01 2010-02-24 先进视觉疗法公司 以炎症为特征的疾病的治疗
CA2678774A1 (en) * 2007-03-01 2008-09-04 Advanced Vision Therapies, Inc. Treatment of diseases characterized by inflammation
DK2191001T3 (en) 2007-04-09 2016-09-19 Univ Florida RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
GB0816702D0 (en) * 2008-09-12 2008-10-22 Trinity College Dublin Complement proteins
GB0904427D0 (en) * 2009-03-13 2009-04-29 Lachmann Peter Treatment of diseases related to hyperactivity of the complement system
TWI775096B (zh) * 2012-05-15 2022-08-21 澳大利亞商艾佛蘭屈澳洲私營有限公司 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
AU2014209350B8 (en) * 2013-01-23 2019-04-18 Department Of Veterans Affairs (Us) Targeting constructs based on natural antibodies and uses thereof
US20140234275A1 (en) * 2013-02-15 2014-08-21 Jason Williams Method for treating als via the increased production of factor h
CN105682674A (zh) * 2013-04-17 2016-06-15 建新公司 用于治疗和预防黄斑变性的组合物和方法
EP3013946B8 (en) * 2013-06-28 2019-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for expressing a polynucleotide of interest in the retina of a subject
GB201403684D0 (en) * 2014-03-03 2014-04-16 King S College London Vector
GB201519086D0 (en) * 2015-10-28 2015-12-09 Syncona Partners Llp Gene Therapy
GB201608046D0 (en) * 2016-05-09 2016-06-22 Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The Treatment of complement-mediated disorders

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