JP2022084930A - 注射ペン - Google Patents
注射ペン Download PDFInfo
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- JP2022084930A JP2022084930A JP2022059961A JP2022059961A JP2022084930A JP 2022084930 A JP2022084930 A JP 2022084930A JP 2022059961 A JP2022059961 A JP 2022059961A JP 2022059961 A JP2022059961 A JP 2022059961A JP 2022084930 A JP2022084930 A JP 2022084930A
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- 238000002347 injection Methods 0.000 title claims abstract description 80
- 239000007924 injection Substances 0.000 title claims abstract description 80
- 239000003814 drug Substances 0.000 claims abstract description 18
- 229940079593 drug Drugs 0.000 claims abstract description 18
- 230000008878 coupling Effects 0.000 claims description 11
- 238000010168 coupling process Methods 0.000 claims description 11
- 238000005859 coupling reaction Methods 0.000 claims description 11
- 230000004048 modification Effects 0.000 claims description 6
- 238000012986 modification Methods 0.000 claims description 6
- 239000000243 solution Substances 0.000 abstract 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 16
- 101000579646 Penaeus vannamei Penaeidin-1 Proteins 0.000 description 9
- 102000004877 Insulin Human genes 0.000 description 8
- 108090001061 Insulin Proteins 0.000 description 8
- 229940125396 insulin Drugs 0.000 description 8
- 238000010999 medical injection Methods 0.000 description 5
- 210000003813 thumb Anatomy 0.000 description 4
- 239000012530 fluid Substances 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- 238000007920 subcutaneous administration Methods 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 239000000806 elastomer Substances 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 239000011324 bead Substances 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
本出願は、参照によりその全体が本明細書に組み込まれている、2013年8月2日に出願された米国特許仮出願第61/861,918号明細書の優先権を主張するものである。
注射ペン1が、ペンの非使用時にカートリッジホルダを覆うためにカートリッジホルダ3に取り外し可能に取り付けられるキャップ5を有する。ペンニードル151がカートリッジホルダのねじ切り部分11に接続される。ペンニードルが、カートリッジ内に保管される薬物のための流路を作ることを目的としてカートリッジホルダ3内に配置されるカートリッジ4の隔壁45を貫通する第1の端部を有するニードルを有する。キャップ5が、誤ってニードルが突き刺さるのを実質的に防止するためにペンニードルのニードルを覆う。
Claims (14)
- 引込ナットを含むハウジングと、
回転方向において前記引込ナットに固定され、前記ハウジング内を軸方向に移動可能なリードスクリュと、
投与量を設定し、投与量を修正するための投与量設定部材であって、前記投与量設定部材は、歯および内部ショルダを備え、前記ハウジングに接続される、投与量設定部材と、
タブと、拡大ヘッド部分と、歯とを備えるセットバック部材であって、前記拡大ヘッド部分は、投与量を設定する間および投与量を修正する間に、前記投与量設定部材の前記内部ショルダに作動的に接続される、セットバック部材と、
前記セットバック部材の前記タブに作動的に接続された溝を備える回転可能な駆動部であって、前記回転可能な駆動部は前記リードスクリュに作動的に接続される、回転可能な駆動部と
を備え、
前記回転可能な駆動部は、投与量を設定する間および投与量を修正する間に、回転することが防止され、
注射中、前記引込ナットは、前記リードスクリュが前記ハウジングに対して回転することを防止するために、前記ハウジングに対して回転方向において固定され、前記投与量設定部材の歯は、前記セットバック部材の歯に係合することにより、前記回転可能な駆動部を回転させて前記リードスクリュを軸方向に移動させて薬を調剤する、注射ペン。 - 前記セットバック部材は、投与量を設定する間および投与量を修正する間に前記ハウジングに対して回転することなく前記投与量設定部材に対して軸方向に移動し、注射中に前記投与量設定部材とともに回転することを特徴とする請求項1に記載の注射ペン。
- 前記セットバック部材は前記回転可能な駆動部に対して軸方向に移動可能であることを特徴とする請求項1および請求項2のいずれか一項に記載の注射ペン。
- 前記セットバック部材は、注射中、前記投与量設定部材と結合して、前記セットバック部材および前記投与量設定部材が回転方向にロックされることを特徴とする請求項1~請求項3のいずれか一項に記載の注射ペン。
- 前記投与量設定部材は第1の歯のセットを含み、前記セットバック部材は、注射中、前記第1の歯のセットと結合する少なくとも1つの第2の歯を含むことを特徴とする請求項1~請求項4のいずれか一項に記載の注射ペン。
- 前記投与量設定部材に連結されたクリッカおよびプッシュボタンをさらに備えることを特徴とする請求項1~請求項5のいずれか一項に記載の注射ペン。
- 注射中に前記プッシュボタンに加えられる力によって、前記投与量設定部材に対する前記セットバック部材の係合が生じることを特徴とする請求項6に記載の注射ペン。
- 前記投与量設定部材は、第1の結合用形状的特徴を有し、
前記セットバック部材は、前記第1の結合用形状的特徴に係合するための第2の結合用形状的特徴を有し、
前記注射ペンは、前記セットバック部材に作動的に接続され、注射中、前記第1の結合用形状的特徴に対する前記第2の結合用形状的特徴の係合を生じさせるプッシュボタンをさらに含み、
前記第1の結合用形状的特徴は、投与量を設定する間および投与量を修正する間に前記第2の結合用形状的特徴から外れ、注射中に前記第2の結合用形状的特徴に係合することを特徴とする請求項1に記載の注射ペン。 - 前記回転可能な駆動部は、前記セットバック部材に対して回転方向にロックされることを特徴とする請求項1,請求項2又は請求項8に記載の注射ペン。
- 前記投与量設定部材は、投与量を設定するべく前記ハウジングから第1方向に回転し、前記投与量設定部材は投与量を修正するべく第2方向に自由に回転可能であることを特徴とする請求項1,請求項8および請求項9のいずれか一項に記載の注射ペン。
- 前記第1の結合用形状的特徴は第1の歯のセットを含み、前記第2の結合用形状的特徴は少なくとも1つの第2の歯を含むことを特徴とする請求項8に記載の注射ペン。
- 前記注射ペンは、カートリッジホルダをさらに備え、
前記カートリッジホルダおよび前記引込ナットは、前記ハウジングに接続され、前記リードスクリュを受容することを特徴とする請求項1~請求項11のいずれか一項に記載の注射ペン。 - 前記カートリッジホルダが前記ハウジングに接続されないとき、前記リードスクリュが前記引込ナットに対して回転し、前記カートリッジホルダが前記ハウジングに接続されたとき、前記リードスクリュが回転方向において前記引込ナットに固定されることを特徴とする請求項12に記載の注射ペン。
- 前記セットバック部材および前記投与量設定部材に作動的に連結されたクリッカをさらに備えることを特徴とする請求項1に記載の注射ペン。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361861918P | 2013-08-02 | 2013-08-02 | |
US61/861,918 | 2013-08-02 | ||
JP2020170755A JP7053755B2 (ja) | 2013-08-02 | 2020-10-08 | 注射ペン |
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JP2020170755A Division JP7053755B2 (ja) | 2013-08-02 | 2020-10-08 | 注射ペン |
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JP2022084930A true JP2022084930A (ja) | 2022-06-07 |
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Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016531861A Active JP6480443B2 (ja) | 2013-08-02 | 2014-07-30 | 注射ペン |
JP2019020728A Active JP6777776B2 (ja) | 2013-08-02 | 2019-02-07 | 注射ペン |
JP2020170755A Active JP7053755B2 (ja) | 2013-08-02 | 2020-10-08 | 注射ペン |
JP2022059961A Pending JP2022084930A (ja) | 2013-08-02 | 2022-03-31 | 注射ペン |
Family Applications Before (3)
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JP2016531861A Active JP6480443B2 (ja) | 2013-08-02 | 2014-07-30 | 注射ペン |
JP2019020728A Active JP6777776B2 (ja) | 2013-08-02 | 2019-02-07 | 注射ペン |
JP2020170755A Active JP7053755B2 (ja) | 2013-08-02 | 2020-10-08 | 注射ペン |
Country Status (13)
Country | Link |
---|---|
US (3) | US10357614B2 (ja) |
EP (2) | EP4011421A3 (ja) |
JP (4) | JP6480443B2 (ja) |
CN (1) | CN104338211B (ja) |
AU (1) | AU2014296217B2 (ja) |
BR (2) | BR112016002356B1 (ja) |
CA (1) | CA2918802C (ja) |
DK (1) | DK3027249T3 (ja) |
ES (1) | ES2909901T3 (ja) |
MX (2) | MX2016001245A (ja) |
PL (1) | PL3027249T3 (ja) |
SG (1) | SG11201600439SA (ja) |
WO (1) | WO2015017550A1 (ja) |
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