JP2021536260A5 - - Google Patents

Info

Publication number
JP2021536260A5
JP2021536260A5 JP2021512665A JP2021512665A JP2021536260A5 JP 2021536260 A5 JP2021536260 A5 JP 2021536260A5 JP 2021512665 A JP2021512665 A JP 2021512665A JP 2021512665 A JP2021512665 A JP 2021512665A JP 2021536260 A5 JP2021536260 A5 JP 2021536260A5
Authority
JP
Japan
Prior art keywords
antigen
car
cells
binds
blcl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021512665A
Other languages
English (en)
Japanese (ja)
Other versions
JP7528059B2 (ja
JP2021536260A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/050404 external-priority patent/WO2020055862A1/en
Publication of JP2021536260A publication Critical patent/JP2021536260A/ja
Publication of JP2021536260A5 publication Critical patent/JP2021536260A5/ja
Priority to JP2024118790A priority Critical patent/JP2024153743A/ja
Application granted granted Critical
Publication of JP7528059B2 publication Critical patent/JP7528059B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021512665A 2018-09-10 2019-09-10 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用 Active JP7528059B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024118790A JP2024153743A (ja) 2018-09-10 2024-07-24 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862729089P 2018-09-10 2018-09-10
US62/729,089 2018-09-10
US201962896707P 2019-09-06 2019-09-06
US62/896,707 2019-09-06
PCT/US2019/050404 WO2020055862A1 (en) 2018-09-10 2019-09-10 Methods for expanding antigen-specific car-t cells, compositions and uses related thereto

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024118790A Division JP2024153743A (ja) 2018-09-10 2024-07-24 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用

Publications (3)

Publication Number Publication Date
JP2021536260A JP2021536260A (ja) 2021-12-27
JP2021536260A5 true JP2021536260A5 (https=) 2022-09-16
JP7528059B2 JP7528059B2 (ja) 2024-08-05

Family

ID=69778136

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021512665A Active JP7528059B2 (ja) 2018-09-10 2019-09-10 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用
JP2024118790A Pending JP2024153743A (ja) 2018-09-10 2024-07-24 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024118790A Pending JP2024153743A (ja) 2018-09-10 2024-07-24 抗原特異的car-t細胞を拡大増殖する方法、それに関連する組成物及び使用

Country Status (13)

Country Link
US (1) US20210301255A1 (https=)
EP (2) EP3849571B1 (https=)
JP (2) JP7528059B2 (https=)
KR (1) KR20210061361A (https=)
CN (1) CN112969470A (https=)
AU (1) AU2019338307A1 (https=)
BR (1) BR112021004465A2 (https=)
CA (1) CA3111796A1 (https=)
ES (1) ES3000183T3 (https=)
IL (1) IL281187A (https=)
MX (1) MX2021002702A (https=)
SG (1) SG11202101468XA (https=)
WO (1) WO2020055862A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210301255A1 (en) * 2018-09-10 2021-09-30 Atara Biotherapeutics, Inc. Methods for expanding antigen-specific car-t cells, compositions and uses related thereto
AU2019372673A1 (en) 2018-11-01 2021-05-27 Gracell Biotechnologies (Shanghai) Co., Ltd. Compositions and methods for T cell engineering
CA3120563A1 (en) 2018-11-26 2020-06-04 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
KR20210125986A (ko) * 2018-12-07 2021-10-19 그라셀 바이오테크놀로지스 (상하이) 컴퍼니, 리미티드 면역요법을 위한 조성물 및 방법
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
EP4281566A1 (en) * 2021-01-20 2023-11-29 Coding Bio Limited Methods for high throughput screening of chimeric antigen receptors
WO2023015310A2 (en) * 2021-08-06 2023-02-09 Seattle Children's Hospital D/B/A Seattle Children's Research Institute T-cell manufacturing methods
CN119317705A (zh) * 2022-02-15 2025-01-14 马克治疗公司 用于抗原特异性t细胞扩增的组合物和方法
CA3254198A1 (en) * 2022-05-27 2023-11-30 Kite Pharma, Inc. Compositions and methods for preparing engineered lymphocytes for cell therapy
AU2024355525A1 (en) * 2023-10-03 2026-04-02 Atara Biotherapeutics, Inc. Bispecific cd19/cd20-targeted chimeric antigen receptors and uses thereof

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
WO2003057171A2 (en) 2002-01-03 2003-07-17 The Trustees Of The University Of Pennsylvania Activation and expansion of t-cells using an engineered multivalent signaling platform
US7976845B2 (en) 2004-11-29 2011-07-12 The Council Of The Queensland Institute Of Medical Research Human cytomegalovirus immunotherapy
KR101749195B1 (ko) 2011-12-12 2017-06-20 셀 메디카 리미티드 T 세포들을 증식시키는 방법
EP2909238A4 (en) 2012-10-19 2016-11-30 Queensland Inst Med Res IMPROVED IMMUNOTHERAPY AGAINST HUMAN HERPESVIRUS
CN104462128B (zh) 2013-09-22 2018-04-13 腾讯科技(深圳)有限公司 多媒体文件处理的方法、装置和终端设备
WO2015154012A1 (en) * 2014-04-03 2015-10-08 Memorial Sloan-Kettering Cancer Center Clonogenic natural killer (nk) cell populations and methods of producing and using such populations
JP6816031B2 (ja) * 2015-02-10 2021-01-20 オレゴン ヘルス アンド サイエンス ユニバーシティ 非標準的なcd8+t細胞応答を生成するのに有用な方法および組成物
US20180214527A1 (en) * 2015-03-26 2018-08-02 City Of Hope Bi-specific targeted chimeric antigen receptor t cells
EP3322424B1 (en) * 2015-07-16 2023-10-11 Yeda Research and Development Co., Ltd. Use of anti third party central memory t cells
AU2017271136A1 (en) 2016-05-23 2019-01-03 The Council Of The Queensland Institute Of Medical Research CMV epitopes
IL262989B2 (en) 2016-05-25 2025-08-01 Council Queensland Inst Medical Res Methods for treating autoimmune disease using allogeneic T cells
MX2019002566A (es) 2016-09-09 2019-12-05 Atara Biotherapeutics Inc Inmunoterapia para poliomavirus.
JP7002769B2 (ja) * 2016-09-16 2022-02-04 ベイラー カレッジ オブ メディスン ウイルス特異的t細胞の活性化および拡大のためのプラットフォーム
US11116834B2 (en) * 2016-10-19 2021-09-14 City Of Hope Use of endogenous viral vaccine in chimeric antigen receptor T cell therapy
KR20200027508A (ko) 2017-07-07 2020-03-12 에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨 돌연변이된 cd28 공동자극 도메인을 갖는 키메라 항원 수용체
JP7416695B2 (ja) 2017-12-29 2024-01-17 メモリアル スローン-ケタリング キャンサー センター 増強されたキメラ抗原受容体およびその使用
US20210301255A1 (en) * 2018-09-10 2021-09-30 Atara Biotherapeutics, Inc. Methods for expanding antigen-specific car-t cells, compositions and uses related thereto

Similar Documents

Publication Publication Date Title
JP2021536260A5 (https=)
Maldini et al. CAR T cells for infection, autoimmunity and allotransplantation
KR102768263B1 (ko) Nk 세포 형질도입 방법
Tey et al. Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation
Ptáčková et al. A new approach to CAR T-cell gene engineering and cultivation using piggyBac transposon in the presence of IL-4, IL-7 and IL-21
CN112204133B (zh) Car nk细胞
AU2017330379B2 (en) Generation and use in adoptive immunotherapy of stem cell-like memory T cells
CN111566201A (zh) 使用用于表达嵌合抗原受体(car)或转基因t细胞受体(tcr)的病毒载体转导细胞的方法
US9670459B2 (en) Production method for cell populations
Xu et al. Toward precision manufacturing of immunogene T-cell therapies
MXPA04009287A (es) Proceso para producir linfocito citotoxico.
JP2025534646A (ja) レンチウイルスベクター導入による新規な大規模car-t免疫細胞の製造方法
JPH11509411A (ja) 樹状細胞のインビトロ増殖のための方法、三次元マトリクス中にエントラップされたその細胞を含む組成物、および免疫のための使用
Li et al. Preclinical development and clinical-scale manufacturing of HIV Gag-specific, lentivirusmodified CD4 T cells for HIV functional cure
WO2022040631A1 (en) Methods for isolating cd8+ selected t cells
JP7626780B2 (ja) 遺伝子改変自己t細胞を製造するためのプロセス
Zhou et al. CD123 redirected multiple virus-specific T cells for acute myeloid leukemia
Wang et al. Alloreactive-free CAR-VST therapy: a step forward in long-term tumor control in viral context
Jurgens et al. Transduction of primary lymphocytes with Epstein-Barr virus (EBV) latent membrane protein-specific T-cell receptor induces lysis of virus-infected cells: a novel strategy for the treatment of Hodgkin's disease and nasopharyngeal carcinoma
US20250101467A1 (en) Preparation technique for universal car-t cell, and use of universal car-t cell thereof
Muñoz et al. Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells
RU2021109354A (ru) Способы экспандирования антигенспецифических car-t-клеток, композиции и применения, связанные с ними
Fesnak et al. Immunotherapy with Autologous Cells
Savoldo et al. therapy: a step forward in long-term tumor control
Lara de León Development of Epstein-Barr Virus-Specific T cells expressing anti-CD19 Chimeric Antigen Receptor for cancer immunotherapy