JP2021535761A5 - - Google Patents
Info
- Publication number
- JP2021535761A5 JP2021535761A5 JP2021539337A JP2021539337A JP2021535761A5 JP 2021535761 A5 JP2021535761 A5 JP 2021535761A5 JP 2021539337 A JP2021539337 A JP 2021539337A JP 2021539337 A JP2021539337 A JP 2021539337A JP 2021535761 A5 JP2021535761 A5 JP 2021535761A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- protein according
- spd
- domain
- cancer
- Prior art date
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862731488P | 2018-09-14 | 2018-09-14 | |
| US62/731,488 | 2018-09-14 | ||
| US201962888320P | 2019-08-16 | 2019-08-16 | |
| US62/888,320 | 2019-08-16 | ||
| PCT/US2019/050742 WO2020056085A1 (en) | 2018-09-14 | 2019-09-12 | Spd-1 variant - fc fusion proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021535761A JP2021535761A (ja) | 2021-12-23 |
| JP2021535761A5 true JP2021535761A5 (https=) | 2022-09-07 |
| JPWO2020056085A5 JPWO2020056085A5 (https=) | 2022-09-07 |
Family
ID=68211179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021539337A Pending JP2021535761A (ja) | 2018-09-14 | 2019-09-12 | ｓＰＤ−１バリアント−Ｆｃ融合タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11498955B2 (https=) |
| EP (1) | EP3850003A1 (https=) |
| JP (1) | JP2021535761A (https=) |
| KR (1) | KR20210058902A (https=) |
| CN (1) | CN112969710A (https=) |
| AU (1) | AU2019338416A1 (https=) |
| CA (1) | CA3109983A1 (https=) |
| NZ (1) | NZ774126A (https=) |
| SG (1) | SG11202101904UA (https=) |
| TW (2) | TWI815964B (https=) |
| WO (1) | WO2020056085A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016164428A1 (en) * | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Receptor-based antagonists of the programmed cell death 1 (pd-1) pathway |
| EP3991741A1 (en) * | 2020-11-02 | 2022-05-04 | Klinikum rechts der Isar der Technischen Universität München | An immune checkpoint-modulating vsv-ndv hybrid virus for oncolytic virus immonotherapy of cancer |
| EP4243852A4 (en) * | 2020-11-13 | 2024-12-11 | Ludwig Institute for Cancer Research Ltd | PD-1 DECOY VARIANTS FOR IMMUNOTHERAPY |
| WO2022137186A1 (en) | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Cancer treatment using cd38 inhibitor and/or lenalidomide and t-cells expressing a chimeric antigen receptor |
| EP4274852A4 (en) * | 2021-01-11 | 2025-02-26 | Eutilex Co., Ltd. | BISPECIFIC EPITOP-BINDING PROTEIN WITH ANTI-4-1BB ANTIBODY AND PD-1 PROTEIN OR FRAGMENTS THEREOF AND USE THEREOF |
| EP4288080A1 (en) * | 2021-02-04 | 2023-12-13 | Helsingin Yliopisto | A cross-hybrid fc-fusion polypeptide targeting pd-l1 and methods and uses related thereto |
| US20240141014A1 (en) * | 2021-03-03 | 2024-05-02 | Shattuck Labs, Inc. | Mutant pd-1 extracellular domains |
| WO2022238962A1 (en) | 2021-05-12 | 2022-11-17 | Crispr Therapeutics Ag | Genetically engineered immune cells targeting cd70 for use in treating hematopoietic malignancies |
| US20250115657A1 (en) * | 2021-05-28 | 2025-04-10 | Akso Biopharmaceutical, Inc. | Bispecific FC Fusion Proteins with sPD-1 and IL-15 |
| WO2023048518A1 (ko) * | 2021-09-24 | 2023-03-30 | 바이오엔시스템스 주식회사 | Pd-1 및 il-15를 포함하는 융합단백질 이량체 및 이의 용도 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2693504A1 (en) * | 2007-08-03 | 2009-02-12 | Eli Lilly And Company | Treatment for obesity |
| CN103261217B (zh) * | 2010-11-11 | 2017-04-26 | 港大科桥有限公司 | 可溶性 pd‑1变体、融合构建体及其用途 |
| US20150368316A1 (en) | 2013-02-07 | 2015-12-24 | Albert Einstein College Of Medicine Of Yeshiva University | A selective high-affinity immune stimulatory reagent and uses thereof |
| US9546206B2 (en) * | 2014-08-08 | 2017-01-17 | The Board Of Trustees Of The Leland Stanford Junior University | High affinity PD-1 agents and methods of use |
| WO2016023001A1 (en) * | 2014-08-08 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | Multispecific high affinity pd-1 agents and methods of use |
| WO2016164428A1 (en) | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Receptor-based antagonists of the programmed cell death 1 (pd-1) pathway |
| EP3303383A1 (en) * | 2015-06-05 | 2018-04-11 | iBio, Inc. | Endostatin fragments and variants for use in treating fibrosis |
| PL3368572T3 (pl) * | 2015-10-02 | 2022-09-12 | Symphogen A/S | Przeciwciała anty-PD-1 oraz kompozycje |
| WO2017123548A1 (en) | 2016-01-14 | 2017-07-20 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Tumor-specific ifna secretion by car t-cells to reprogram the solid tumor microenvironment |
| WO2018104473A1 (en) * | 2016-12-07 | 2018-06-14 | Oslo Universitetssykehus Hf | Compositions and methods for cell therapy |
| US12065476B2 (en) * | 2018-06-15 | 2024-08-20 | Alpine Immune Sciences, Inc. | PD-1 variant immunomodulatory proteins and uses thereof |
-
2019
- 2019-09-12 NZ NZ774126A patent/NZ774126A/en not_active IP Right Cessation
- 2019-09-12 SG SG11202101904UA patent/SG11202101904UA/en unknown
- 2019-09-12 CA CA3109983A patent/CA3109983A1/en active Pending
- 2019-09-12 US US16/569,105 patent/US11498955B2/en active Active
- 2019-09-12 WO PCT/US2019/050742 patent/WO2020056085A1/en not_active Ceased
- 2019-09-12 EP EP19786693.2A patent/EP3850003A1/en not_active Withdrawn
- 2019-09-12 CN CN201980060042.5A patent/CN112969710A/zh active Pending
- 2019-09-12 TW TW108133070A patent/TWI815964B/zh active
- 2019-09-12 KR KR1020217010801A patent/KR20210058902A/ko not_active Ceased
- 2019-09-12 AU AU2019338416A patent/AU2019338416A1/en not_active Abandoned
- 2019-09-12 JP JP2021539337A patent/JP2021535761A/ja active Pending
- 2019-09-12 TW TW112132395A patent/TW202348622A/zh unknown
-
2022
- 2022-10-10 US US17/962,983 patent/US20230131056A1/en not_active Abandoned
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