JP2021535761A5 - - Google Patents
Info
- Publication number
- JP2021535761A5 JP2021535761A5 JP2021539337A JP2021539337A JP2021535761A5 JP 2021535761 A5 JP2021535761 A5 JP 2021535761A5 JP 2021539337 A JP2021539337 A JP 2021539337A JP 2021539337 A JP2021539337 A JP 2021539337A JP 2021535761 A5 JP2021535761 A5 JP 2021535761A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- protein according
- spd
- domain
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862731488P | 2018-09-14 | 2018-09-14 | |
| US62/731,488 | 2018-09-14 | ||
| US201962888320P | 2019-08-16 | 2019-08-16 | |
| US62/888,320 | 2019-08-16 | ||
| PCT/US2019/050742 WO2020056085A1 (en) | 2018-09-14 | 2019-09-12 | Spd-1 variant - fc fusion proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021535761A JP2021535761A (ja) | 2021-12-23 |
| JP2021535761A5 true JP2021535761A5 (https=) | 2022-09-07 |
Family
ID=68211179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021539337A Pending JP2021535761A (ja) | 2018-09-14 | 2019-09-12 | ｓＰＤ−１バリアント−Ｆｃ融合タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11498955B2 (https=) |
| EP (1) | EP3850003A1 (https=) |
| JP (1) | JP2021535761A (https=) |
| KR (1) | KR20210058902A (https=) |
| CN (1) | CN112969710A (https=) |
| AU (1) | AU2019338416A1 (https=) |
| CA (1) | CA3109983A1 (https=) |
| NZ (1) | NZ774126A (https=) |
| SG (1) | SG11202101904UA (https=) |
| TW (2) | TW202348622A (https=) |
| WO (1) | WO2020056085A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016164428A1 (en) * | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Receptor-based antagonists of the programmed cell death 1 (pd-1) pathway |
| EP3991741A1 (en) * | 2020-11-02 | 2022-05-04 | Klinikum rechts der Isar der Technischen Universität München | An immune checkpoint-modulating vsv-ndv hybrid virus for oncolytic virus immonotherapy of cancer |
| US20230414660A1 (en) * | 2020-11-13 | 2023-12-28 | Ludwig Institute For Cancer Research Ltd | Pd-1 decoy variants for immunotherapy |
| WO2022137186A1 (en) | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Cancer treatment using cd38 inhibitor and/or lenalidomide and t-cells expressing a chimeric antigen receptor |
| KR102618718B1 (ko) * | 2021-01-11 | 2023-12-29 | 주식회사 유틸렉스 | 항-4-1bb 항체 및 pd-1 단백질 또는 이의 단편을 포함하는 이중특이적 에피토프 결합 단백질 및 이의 용도 |
| WO2022167729A1 (en) * | 2021-02-04 | 2022-08-11 | Helsingin Yliopisto | A cross-hybrid fc-fusion polypeptide targeting pd-l1 and methods and uses related thereto |
| US20240141014A1 (en) * | 2021-03-03 | 2024-05-02 | Shattuck Labs, Inc. | Mutant pd-1 extracellular domains |
| AR125851A1 (es) | 2021-05-12 | 2023-08-16 | Crispr Therapeutics Ag | Células inmunes modificadas genéticamente que se focalizan en cd70 para su uso en el tratamiento de neoplasias malignas hematopoyéticas |
| CA3220027A1 (en) * | 2021-05-28 | 2022-12-01 | Amato J. Giaccia | Bispecific fc fusion proteins with spd-1 and il-15 |
| WO2023048518A1 (ko) * | 2021-09-24 | 2023-03-30 | 바이오엔시스템스 주식회사 | Pd-1 및 il-15를 포함하는 융합단백질 이량체 및 이의 용도 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110034373A1 (en) * | 2007-08-03 | 2011-02-10 | Eli Lilly And Company | Use of an fgf-21 compound and a glp-1 compound for the treatment of obesity |
| CN107090029B (zh) * | 2010-11-11 | 2021-07-13 | 港大科桥有限公司 | 可溶性 pd-1变体、融合构建体及其用途 |
| US20150368316A1 (en) * | 2013-02-07 | 2015-12-24 | Albert Einstein College Of Medicine Of Yeshiva University | A selective high-affinity immune stimulatory reagent and uses thereof |
| PT3177640T (pt) * | 2014-08-08 | 2020-08-31 | Univ Leland Stanford Junior | Agentes pd-1 de alta afinidade e métodos de utilização |
| WO2016023001A1 (en) * | 2014-08-08 | 2016-02-11 | The Board Of Trustees Of The Leland Stanford Junior University | Multispecific high affinity pd-1 agents and methods of use |
| WO2016164428A1 (en) * | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Receptor-based antagonists of the programmed cell death 1 (pd-1) pathway |
| CN115925878A (zh) * | 2015-06-05 | 2023-04-07 | 艾比欧公司 | 用于治疗纤维化的内皮抑素片段和变体 |
| ES2924402T3 (es) * | 2015-10-02 | 2022-10-06 | Symphogen As | Anticuerpos anti-PD-1 y composiciones |
| WO2017123548A1 (en) | 2016-01-14 | 2017-07-20 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Tumor-specific ifna secretion by car t-cells to reprogram the solid tumor microenvironment |
| US20190358263A1 (en) * | 2016-12-07 | 2019-11-28 | Oslo Universitetssykehus Hf | Compositions and Methods for Cell Therapy |
| WO2019241758A1 (en) * | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
-
2019
- 2019-09-12 JP JP2021539337A patent/JP2021535761A/ja active Pending
- 2019-09-12 WO PCT/US2019/050742 patent/WO2020056085A1/en not_active Ceased
- 2019-09-12 CN CN201980060042.5A patent/CN112969710A/zh active Pending
- 2019-09-12 NZ NZ774126A patent/NZ774126A/en not_active IP Right Cessation
- 2019-09-12 KR KR1020217010801A patent/KR20210058902A/ko not_active Ceased
- 2019-09-12 EP EP19786693.2A patent/EP3850003A1/en not_active Withdrawn
- 2019-09-12 CA CA3109983A patent/CA3109983A1/en active Pending
- 2019-09-12 TW TW112132395A patent/TW202348622A/zh unknown
- 2019-09-12 US US16/569,105 patent/US11498955B2/en active Active
- 2019-09-12 TW TW108133070A patent/TWI815964B/zh active
- 2019-09-12 SG SG11202101904UA patent/SG11202101904UA/en unknown
- 2019-09-12 AU AU2019338416A patent/AU2019338416A1/en not_active Abandoned
-
2022
- 2022-10-10 US US17/962,983 patent/US20230131056A1/en not_active Abandoned
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