JP2021533801A5 - - Google Patents

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Publication number
JP2021533801A5
JP2021533801A5 JP2021509904A JP2021509904A JP2021533801A5 JP 2021533801 A5 JP2021533801 A5 JP 2021533801A5 JP 2021509904 A JP2021509904 A JP 2021509904A JP 2021509904 A JP2021509904 A JP 2021509904A JP 2021533801 A5 JP2021533801 A5 JP 2021533801A5
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JP
Japan
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sequence
nucleic acid
recombinant nucleic
vector
nucleotide sequence
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JP2021509904A
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English (en)
Japanese (ja)
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JP2021533801A (ja
JP7285022B2 (ja
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Priority claimed from CN201810968173.0A external-priority patent/CN110857440B/zh
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JP2021509904A 2018-08-23 2019-08-23 組換えヒトII型ミトコンドリアダイニン様GTPaseの遺伝子配列及びその使用 Active JP7285022B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201810968173.0 2018-08-23
CN201810968173.0A CN110857440B (zh) 2018-08-23 2018-08-23 重组人ⅱ型线粒体动力蛋白样gtp酶基因序列及其应用
PCT/CN2019/102352 WO2020038473A1 (zh) 2018-08-23 2019-08-23 重组人ⅱ型线粒体动力蛋白样gtp酶基因序列及其应用

Publications (3)

Publication Number Publication Date
JP2021533801A JP2021533801A (ja) 2021-12-09
JP2021533801A5 true JP2021533801A5 (enExample) 2022-08-31
JP7285022B2 JP7285022B2 (ja) 2023-06-01

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JP2021509904A Active JP7285022B2 (ja) 2018-08-23 2019-08-23 組換えヒトII型ミトコンドリアダイニン様GTPaseの遺伝子配列及びその使用

Country Status (11)

Country Link
US (1) US11459584B2 (enExample)
EP (1) EP3851535A4 (enExample)
JP (1) JP7285022B2 (enExample)
KR (1) KR102612148B1 (enExample)
CN (1) CN110857440B (enExample)
AU (1) AU2019323501B2 (enExample)
BR (1) BR112021002566A2 (enExample)
CA (1) CA3110153A1 (enExample)
MX (1) MX2021002135A (enExample)
SG (1) SG11202101236WA (enExample)
WO (1) WO2020038473A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110857440B (zh) 2018-08-23 2021-02-19 武汉纽福斯生物科技有限公司 重组人ⅱ型线粒体动力蛋白样gtp酶基因序列及其应用
CN111849998A (zh) * 2020-07-29 2020-10-30 武汉纽福斯生物科技有限公司 编码人卵黄状黄斑病蛋白1的核酸分子及其应用
CN117904156A (zh) * 2022-10-17 2024-04-19 武汉纽福斯生物科技有限公司 人线粒体动力蛋白样gtp酶及应用
WO2024226729A2 (en) * 2023-04-26 2024-10-31 Astellas Gene Therapies, Inc. Compositions and methods for opa1 gene therapy
CN117304293B (zh) * 2023-10-07 2025-08-08 浙江大学 一种鸡opa1抗原决定簇及其应用

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US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
AU7906691A (en) 1990-05-23 1991-12-10 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Adeno-associated virus (aav)-based eucaryotic vectors
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US6566118B1 (en) 1997-09-05 2003-05-20 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6989264B2 (en) 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
EP2369002A1 (en) 1999-08-09 2011-09-28 Targeted Genetics Corporation Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms intrastrand base pairs
WO2006073496A2 (en) 2004-07-30 2006-07-13 Targeted Genetics Corporation Recombinant aav based vaccine methods
PT1880008E (pt) * 2005-05-03 2015-08-27 Inserm Inst Nat De La Santé Et De La Rech Médicale Expressão de proteína mitocondrial através de uma abordagem alotópica melhorada
EP2030021B1 (en) * 2006-05-18 2012-11-21 Andreas Reichert Method for diagnosing mitochondrial dysfunction
CN102634527B (zh) * 2012-04-11 2013-11-06 华中科技大学同济医学院附属同济医院 重组人nadh脱氢酶亚单位4基因及其表达载体构建方法
JP2015527889A (ja) * 2012-07-25 2015-09-24 ザ ブロード インスティテュート, インコーポレイテッド 誘導可能なdna結合タンパク質およびゲノム撹乱ツール、ならびにそれらの適用
TW201514200A (zh) * 2013-04-03 2015-04-16 Aliophtha Ag 用於治療由opa1單倍體不足所造成的疾病之人工轉錄因子
CN104450747B (zh) * 2014-09-23 2018-02-09 武汉纽福斯生物科技有限公司 用于治疗Leber遗传性视神经病变的重组腺相关病毒‑NADH脱氢酶亚单位4基因全长以及药剂
US20190275168A1 (en) * 2015-04-30 2019-09-12 The Trustees Of Columbia University In The City Of New York Gene therapy for autosomal dominant diseases
WO2017191274A2 (en) * 2016-05-04 2017-11-09 Curevac Ag Rna encoding a therapeutic protein
WO2018102672A1 (en) * 2016-12-04 2018-06-07 Alavi Khorassani Moghadam Marcel Victor Methods for treating diseases related to mitochondrial stress
CN110392582A (zh) * 2017-02-08 2019-10-29 弗里德里克·米谢尔生物医学研究所 用于使基因在视网膜神经节细胞中特异性表达的启动子SynP88
CN111068071A (zh) * 2018-10-22 2020-04-28 武汉纽福斯生物科技有限公司 基因治疗Leber遗传学视神经病变
CN110857440B (zh) 2018-08-23 2021-02-19 武汉纽福斯生物科技有限公司 重组人ⅱ型线粒体动力蛋白样gtp酶基因序列及其应用

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