JP2021528057A5 - - Google Patents

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Publication number
JP2021528057A5
JP2021528057A5 JP2020569099A JP2020569099A JP2021528057A5 JP 2021528057 A5 JP2021528057 A5 JP 2021528057A5 JP 2020569099 A JP2020569099 A JP 2020569099A JP 2020569099 A JP2020569099 A JP 2020569099A JP 2021528057 A5 JP2021528057 A5 JP 2021528057A5
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JP
Japan
Prior art keywords
gene segment
human
unreconstructed
rodent
gene
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JP2020569099A
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English (en)
Japanese (ja)
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JP7182647B2 (ja
JP2021528057A (ja
JPWO2019241692A5 (https=
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Priority claimed from PCT/US2019/037285 external-priority patent/WO2019241692A1/en
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Publication of JP2021528057A publication Critical patent/JP2021528057A/ja
Priority to JP2022056227A priority Critical patent/JP2022079617A/ja
Publication of JPWO2019241692A5 publication Critical patent/JPWO2019241692A5/ja
Publication of JP2021528057A5 publication Critical patent/JP2021528057A5/ja
Publication of JP7182647B2 publication Critical patent/JP7182647B2/ja
Application granted granted Critical
Priority to JP2023215643A priority patent/JP2024019660A/ja
Priority to JP2024100324A priority patent/JP7815335B2/ja
Priority to JP2025188198A priority patent/JP2026016787A/ja
Active legal-status Critical Current
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JP2020569099A 2018-06-14 2019-06-14 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物 Active JP7182647B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2022056227A JP2022079617A (ja) 2018-06-14 2022-03-30 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2023215643A JP2024019660A (ja) 2018-06-14 2023-12-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2024100324A JP7815335B2 (ja) 2018-06-14 2024-06-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2025188198A JP2026016787A (ja) 2018-06-14 2025-11-07 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862685203P 2018-06-14 2018-06-14
US62/685,203 2018-06-14
US201862702206P 2018-07-23 2018-07-23
US62/702,206 2018-07-23
US201962812580P 2019-03-01 2019-03-01
US62/812,580 2019-03-01
PCT/US2019/037285 WO2019241692A1 (en) 2018-06-14 2019-06-14 Non-human animals capable of dh-dh rearrangement in the immunoglobulin heavy chain coding sequences

Related Child Applications (1)

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JP2022056227A Division JP2022079617A (ja) 2018-06-14 2022-03-30 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物

Publications (4)

Publication Number Publication Date
JP2021528057A JP2021528057A (ja) 2021-10-21
JP2021528057A5 true JP2021528057A5 (https=) 2022-04-08
JPWO2019241692A5 JPWO2019241692A5 (https=) 2022-04-08
JP7182647B2 JP7182647B2 (ja) 2022-12-02

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ID=67220854

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2020569099A Active JP7182647B2 (ja) 2018-06-14 2019-06-14 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2022056227A Withdrawn JP2022079617A (ja) 2018-06-14 2022-03-30 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2023215643A Withdrawn JP2024019660A (ja) 2018-06-14 2023-12-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2024100324A Active JP7815335B2 (ja) 2018-06-14 2024-06-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2025188198A Pending JP2026016787A (ja) 2018-06-14 2025-11-07 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物

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JP2022056227A Withdrawn JP2022079617A (ja) 2018-06-14 2022-03-30 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2023215643A Withdrawn JP2024019660A (ja) 2018-06-14 2023-12-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2024100324A Active JP7815335B2 (ja) 2018-06-14 2024-06-21 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物
JP2025188198A Pending JP2026016787A (ja) 2018-06-14 2025-11-07 免疫グロブリン重鎖コーディング配列におけるｄｈ－ｄｈ再構成が可能な非ヒト動物

Country Status (25)

Country Link
US (2) US20210251202A1 (https=)
EP (3) EP3629720B1 (https=)
JP (5) JP7182647B2 (https=)
KR (3) KR102617284B1 (https=)
CN (2) CN113430207A (https=)
AU (3) AU2019287727B2 (https=)
CA (1) CA3103646C (https=)
CY (1) CY1125121T1 (https=)
DK (2) DK4023059T3 (https=)
ES (2) ES2994581T3 (https=)
FI (1) FI4023059T3 (https=)
HR (2) HRP20220509T8 (https=)
HU (1) HUE069544T2 (https=)
IL (3) IL318469A (https=)
LT (2) LT3629720T (https=)
MX (2) MX391767B (https=)
PL (2) PL4023059T3 (https=)
PT (2) PT4023059T (https=)
RS (2) RS66298B1 (https=)
SG (1) SG11202012084WA (https=)
SI (2) SI3629720T1 (https=)
SM (2) SMT202400501T1 (https=)
TW (2) TWI840372B (https=)
WO (1) WO2019241692A1 (https=)
ZA (1) ZA202007560B (https=)

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WO2026030428A2 (en) 2024-08-01 2026-02-05 Regeneron Pharmaceuticals, Inc. Prostate-specific antigen peptides and uses thereof
WO2026035843A2 (en) 2024-08-06 2026-02-12 Regeneron Pharmaceuticals, Inc. Non-human animals having modified immunoglobulin heavy chain constant region locus and uses thereof

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