JP2021527031A5 - - Google Patents

Info

Publication number
JP2021527031A5
JP2021527031A5 JP2020566701A JP2020566701A JP2021527031A5 JP 2021527031 A5 JP2021527031 A5 JP 2021527031A5 JP 2020566701 A JP2020566701 A JP 2020566701A JP 2020566701 A JP2020566701 A JP 2020566701A JP 2021527031 A5 JP2021527031 A5 JP 2021527031A5
Authority
JP
Japan
Prior art keywords
cocrystal
pharmaceutically acceptable
acceptable salt
subject
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020566701A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021527031A (ja
JP7778477B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/034505 external-priority patent/WO2019232120A1/en
Publication of JP2021527031A publication Critical patent/JP2021527031A/ja
Publication of JP2021527031A5 publication Critical patent/JP2021527031A5/ja
Priority to JP2024030700A priority Critical patent/JP7841008B2/ja
Application granted granted Critical
Publication of JP7778477B2 publication Critical patent/JP7778477B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020566701A 2018-05-30 2019-05-30 セピアプテリンの薬学的に許容される塩 Active JP7778477B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024030700A JP7841008B2 (ja) 2018-05-30 2024-02-29 セピアプテリンの薬学的に許容される塩

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862678025P 2018-05-30 2018-05-30
US62/678,025 2018-05-30
US201862726612P 2018-09-04 2018-09-04
US62/726,612 2018-09-04
US201962822336P 2019-03-22 2019-03-22
US62/822,336 2019-03-22
GC201937661 2019-05-28
GC2019/37661 2019-05-28
PCT/US2019/034505 WO2019232120A1 (en) 2018-05-30 2019-05-30 Pharmaceutically acceptable salts of sepiapterin

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024030700A Division JP7841008B2 (ja) 2018-05-30 2024-02-29 セピアプテリンの薬学的に許容される塩

Publications (3)

Publication Number Publication Date
JP2021527031A JP2021527031A (ja) 2021-10-11
JP2021527031A5 true JP2021527031A5 (enExample) 2022-06-07
JP7778477B2 JP7778477B2 (ja) 2025-12-02

Family

ID=68699017

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020566701A Active JP7778477B2 (ja) 2018-05-30 2019-05-30 セピアプテリンの薬学的に許容される塩
JP2024030700A Active JP7841008B2 (ja) 2018-05-30 2024-02-29 セピアプテリンの薬学的に許容される塩

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024030700A Active JP7841008B2 (ja) 2018-05-30 2024-02-29 セピアプテリンの薬学的に許容される塩

Country Status (13)

Country Link
US (1) US12637465B2 (enExample)
EP (1) EP3807279B1 (enExample)
JP (2) JP7778477B2 (enExample)
KR (1) KR20210038848A (enExample)
CN (1) CN112543758A (enExample)
AU (2) AU2019277372B2 (enExample)
BR (1) BR112020024332A2 (enExample)
CA (1) CA3102070A1 (enExample)
CL (1) CL2020003101A1 (enExample)
CO (1) CO2020016582A2 (enExample)
IL (1) IL279101A (enExample)
MX (1) MX2020012978A (enExample)
WO (1) WO2019232120A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110312721A (zh) 2016-11-29 2019-10-08 显莎制药公司 墨蝶呤的多晶型物
WO2018102315A1 (en) 2016-11-29 2018-06-07 Censa Pharmaceuticals Inc. Polymoprhs of sepiapterin and salts thereof
MX2020002271A (es) 2017-09-01 2020-10-05 Ptc Therapeutics Mp Inc Composiciones farmaceuticas que comprenden sepiapterina y sus usos de las mismas.
CA3102105A1 (en) * 2018-05-30 2019-12-05 Ptc Therapeutics Mp, Inc. Compositions and methods for increasing tetrahydrobiopterin plasma exposure
JP7778477B2 (ja) * 2018-05-30 2025-12-02 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリンの薬学的に許容される塩
JP7502197B2 (ja) 2018-05-30 2024-06-18 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリン血漿曝露を増加させるための方法
LT4009978T (lt) 2019-08-05 2024-11-25 Ptc Therapeutics Mp, Inc. Sepiapterino ir jo metabolitų panaudojimas spinduliuotės poveikio gydymui
IL291565B1 (en) 2019-09-25 2026-04-01 Ptc Therapeutics Inc Method for treating phenylalanine irregularity
CA3165636A1 (en) 2020-01-24 2021-07-29 Neil Smith Methods for treating parkinson's disease with sepiapterin
CN114621198B (zh) * 2020-12-11 2025-01-21 北京夏禾科技有限公司 有机电致发光材料及其器件
US12691119B2 (en) 2021-02-09 2026-07-28 Ptc Therapeutics Mp, Inc. Methods for treating covid-19 with sepiapterin
IL305037A (en) 2021-02-09 2023-10-01 Ptc Therapeutics Mp Inc Methods of treating glioblastomas with spiafatrin

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925323A (ja) 1982-03-03 1984-02-09 鐘淵化学工業株式会社 プテリン誘導体からなる脳内神経伝達物質の関わる疾病の治療剤
US5910304A (en) 1982-12-13 1999-06-08 Texas A&M University System Low-dose oral administration of interferons
CA1320905C (en) 1986-11-06 1993-08-03 Joseph M. Cummins Treatment of immuno-resistant disease
US5753656A (en) * 1994-08-05 1998-05-19 Suntory Limited Method for treating spinocerebellar degeneration
WO1997007236A1 (en) 1995-08-18 1997-02-27 Landry Donald W Detection of organic compounds through regulation of antibody-catalyzed reactions
US6036949A (en) 1998-03-05 2000-03-14 Amarillo Biosciences, Inc. Treatment of fibromyalgia with low doses of interferon
US8188043B2 (en) 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
FR2859996B1 (fr) 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
JP2007509909A (ja) 2003-10-31 2007-04-19 アルタナ ファルマ アクチエンゲゼルシャフト 呼吸器疾患の治療のためのbh4の使用
JP5184783B2 (ja) 2003-11-17 2013-04-17 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリン、及びテトラヒドロビオプテリン類似体の製造方法
CA2545968C (en) 2003-11-17 2010-03-09 Merck Eprova Ag Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
PT3138566T (pt) 2003-11-17 2022-02-02 Biomarin Pharm Inc Tratamento de fenilcetonúria com bh4
CN101132776A (zh) 2004-11-17 2008-02-27 生物马林药物股份有限公司 稳定的四氢生物喋呤片剂制剂
US20100130500A1 (en) 2004-12-08 2010-05-27 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
WO2006118322A1 (en) 2005-04-28 2006-11-09 Shiratori Pharmaceutical Co., Ltd. Method for producing hydrazone derivatives
US20080075666A1 (en) 2006-08-25 2008-03-27 Dudley Samuel C Jr Methods and compositions for treating diastolic dysfunction
KR20160065998A (ko) 2007-04-11 2016-06-09 바이오마린 파머수티컬 인크. 테트라하이드로바이오프테린 투여 방법, 관련 조성물 및 측정 방법
LT2262790T (lt) 2008-03-10 2017-08-25 Takeda Pharmaceutical Company Limited Benzimidazolo junginio kristalas
WO2010017570A2 (de) 2008-08-12 2010-02-18 Orpha Swiss Gmbh Pharmazeutische darreichungsform enthaltend tetrahydrobiopterin
EP2382216A1 (en) 2008-12-23 2011-11-02 Boehringer Ingelheim International GmbH Salt forms of organic compound
IN2012DN01453A (enExample) 2009-08-20 2015-06-05 Novartis Ag
JP5066756B2 (ja) * 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
CA2828685C (en) 2011-03-01 2018-05-29 Rubicon Research Private Limited Stable compositions of tetrahydrobiopterin
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
JP6084967B2 (ja) 2012-05-07 2017-02-22 白鳥製薬株式会社 セピアプテリン及びテトラヒドロラクトイルプテリンの製造法
WO2017218421A1 (en) * 2016-06-13 2017-12-21 Meharry Medical College Modulation of the nitric oxide synthase pathway for oral health
WO2018019931A1 (en) 2016-07-29 2018-02-01 Dipharma S.A. Pharmaceutical composition kit comprising sapropterin dihydrochloride
WO2018102315A1 (en) 2016-11-29 2018-06-07 Censa Pharmaceuticals Inc. Polymoprhs of sepiapterin and salts thereof
CN110312721A (zh) 2016-11-29 2019-10-08 显莎制药公司 墨蝶呤的多晶型物
BR102018007822A2 (pt) 2017-04-20 2018-11-06 Gilead Sciences, Inc. composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
MX2020002271A (es) 2017-09-01 2020-10-05 Ptc Therapeutics Mp Inc Composiciones farmaceuticas que comprenden sepiapterina y sus usos de las mismas.
CA3102105A1 (en) 2018-05-30 2019-12-05 Ptc Therapeutics Mp, Inc. Compositions and methods for increasing tetrahydrobiopterin plasma exposure
JP7778477B2 (ja) * 2018-05-30 2025-12-02 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリンの薬学的に許容される塩
JP7502197B2 (ja) 2018-05-30 2024-06-18 ピーティーシー セラピューティクス エムピー,インコーポレイテッド セピアプテリン血漿曝露を増加させるための方法
LT4009978T (lt) 2019-08-05 2024-11-25 Ptc Therapeutics Mp, Inc. Sepiapterino ir jo metabolitų panaudojimas spinduliuotės poveikio gydymui
IL291565B1 (en) 2019-09-25 2026-04-01 Ptc Therapeutics Inc Method for treating phenylalanine irregularity

Similar Documents

Publication Publication Date Title
JP2024063143A5 (enExample)
ZA202001390B (en) Crystalline forms
KR102425226B1 (ko) Jak 저해제를 포함하는 제약 조성물
AU2025213591A1 (en) Methods of treating neurological and psychiatric disorders
JP6389498B2 (ja) ニトロカテコールの投与計画
JP2016503010A5 (enExample)
JP2014037426A5 (enExample)
JP2021525729A5 (enExample)
JP2015500236A5 (enExample)
HRP20231533T1 (hr) Kristalni oblici od (s)-1-(4-fluorofenil)-1-(2-(4-(6-(1-metil-1h-pirazol-4-il)pirolo[2,1-f][1,2,4 ]triazin-4-il)piperazinil)-pirimidin-5-il)etan-1-amina i postupci priprave
JP2015509534A5 (enExample)
JP2022502500A5 (enExample)
JP2010505961A5 (enExample)
JP2015509972A5 (enExample)
JP2017538753A5 (enExample)
JP2013506670A5 (enExample)
RU2003121307A (ru) (диазоло-пиридинил)-пиримидины для применения в лечении нарушений центральной нервной системы и диабета
JP2018537513A5 (enExample)
JP2015500223A5 (enExample)
JP5124471B2 (ja) 置換二環式ピリミドン誘導体
JP2024160326A (ja) Eaat2活性化因子およびその使用方法
JP2022514537A5 (enExample)
WO2012031383A1 (zh) 酰胺类化合物
IL292466B2 (en) Isoquinolinone derivatives, method for preparing the same, and pharmaceutical composition for preventing or treating poly(adp-ribose) polymerase-1-related diseases, comprising the same as active ingredient
JP2010520176A5 (enExample)