JP2021526830A5 - - Google Patents

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Publication number
JP2021526830A5
JP2021526830A5 JP2020569001A JP2020569001A JP2021526830A5 JP 2021526830 A5 JP2021526830 A5 JP 2021526830A5 JP 2020569001 A JP2020569001 A JP 2020569001A JP 2020569001 A JP2020569001 A JP 2020569001A JP 2021526830 A5 JP2021526830 A5 JP 2021526830A5
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JP
Japan
Prior art keywords
heavy chain
variable domain
transgenic
gene
transgenic chicken
Prior art date
Application number
JP2020569001A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021526830A (ja
JP7515410B2 (ja
JPWO2019241002A5 (https=
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Priority claimed from PCT/US2019/035540 external-priority patent/WO2019241002A1/en
Publication of JP2021526830A publication Critical patent/JP2021526830A/ja
Publication of JP2021526830A5 publication Critical patent/JP2021526830A5/ja
Publication of JPWO2019241002A5 publication Critical patent/JPWO2019241002A5/ja
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Publication of JP7515410B2 publication Critical patent/JP7515410B2/ja
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JP2020569001A 2018-06-13 2019-06-05 複数のジスルフィド架橋によって安定化され、遺伝子変換によって多様化された長いｃｄｒ－ｈ３ｓで抗体を作製するトランスジェニックニワトリ Active JP7515410B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862684669P 2018-06-13 2018-06-13
US62/684,669 2018-06-13
PCT/US2019/035540 WO2019241002A1 (en) 2018-06-13 2019-06-05 Transgenic chicken that makes antibodies with long cdr-h3s stabilized by multiple disulfide bridges and diversified by gene conversion

Publications (4)

Publication Number Publication Date
JP2021526830A JP2021526830A (ja) 2021-10-11
JP2021526830A5 true JP2021526830A5 (https=) 2022-06-09
JPWO2019241002A5 JPWO2019241002A5 (https=) 2022-06-09
JP7515410B2 JP7515410B2 (ja) 2024-07-12

Family

ID=68842113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020569001A Active JP7515410B2 (ja) 2018-06-13 2019-06-05 複数のジスルフィド架橋によって安定化され、遺伝子変換によって多様化された長いｃｄｒ－ｈ３ｓで抗体を作製するトランスジェニックニワトリ

Country Status (7)

Country Link
US (2) US12428471B2 (https=)
EP (1) EP3813520A4 (https=)
JP (1) JP7515410B2 (https=)
KR (1) KR20210021002A (https=)
AU (2) AU2019284256B2 (https=)
CA (1) CA3102125A1 (https=)
WO (1) WO2019241002A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202430558A (zh) 2023-01-18 2024-08-01 美商基利科學股份有限公司 人類免疫球蛋白重鏈長cdr3轉殖基因構築體及其用途

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US6492107B1 (en) 1986-11-20 2002-12-10 Stuart Kauffman Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
GB2183661B (en) 1985-03-30 1989-06-28 Marc Ballivet Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique
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