JP2021526795A5 - - Google Patents
Info
- Publication number
- JP2021526795A5 JP2021526795A5 JP2020567760A JP2020567760A JP2021526795A5 JP 2021526795 A5 JP2021526795 A5 JP 2021526795A5 JP 2020567760 A JP2020567760 A JP 2020567760A JP 2020567760 A JP2020567760 A JP 2020567760A JP 2021526795 A5 JP2021526795 A5 JP 2021526795A5
- Authority
- JP
- Japan
- Prior art keywords
- caar
- domain
- cells
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862680769P | 2018-06-05 | 2018-06-05 | |
| US62/680,769 | 2018-06-05 | ||
| PCT/US2019/035409 WO2019236593A1 (en) | 2018-06-05 | 2019-06-04 | Compositions and methods of muscle specific kinase chimeric autoantibody receptor cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021526795A JP2021526795A (ja) | 2021-10-11 |
| JP2021526795A5 true JP2021526795A5 (enExample) | 2022-06-08 |
| JP7561036B2 JP7561036B2 (ja) | 2024-10-03 |
Family
ID=68764025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567760A Active JP7561036B2 (ja) | 2018-06-05 | 2019-06-04 | 筋特異的キナーゼキメラ自己受容体細胞の組成物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11905321B2 (enExample) |
| EP (1) | EP3801642A4 (enExample) |
| JP (1) | JP7561036B2 (enExample) |
| KR (1) | KR20210018833A (enExample) |
| CN (1) | CN112423793A (enExample) |
| AU (1) | AU2019282634A1 (enExample) |
| CA (1) | CA3101028A1 (enExample) |
| MX (1) | MX421685B (enExample) |
| WO (1) | WO2019236593A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7702884B2 (ja) * | 2019-06-05 | 2025-07-04 | ドイチェス ツェントラム フューア ノイロデジェネラティヴ エアクランクンゲン エー． ファウ．（ディーゼットエヌイー） | 神経学的自己免疫疾患における中枢神経系を標的とする自己抗体に結合するキメラ自己抗体受容体（ｃａａｒ） |
| CN114075568A (zh) * | 2020-08-18 | 2022-02-22 | 苏州博腾生物制药有限公司 | 靶向烟碱乙酰胆碱受体自身抗体的组合物和方法 |
| US20240041927A1 (en) | 2020-12-22 | 2024-02-08 | Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne) | Chimeric autoantibody receptor (caar) comprising a nicotinic acetylcholine receptor autoantigen |
| JP2024545870A (ja) * | 2021-12-15 | 2024-12-13 | シャンハイ シンヴィダ バイオテクノロジー カンパニー リミテッド | 血小板減少症を治療するための製品及び方法 |
| WO2024059704A1 (en) * | 2022-09-14 | 2024-03-21 | The Johns Hopkins University | Compositions of chimeric autoantigen-t cell receptor (catcr)-t cells and methods of making and using the same |
| WO2024124155A1 (en) * | 2022-12-08 | 2024-06-13 | The Johns Hopkins University | Bispecific autoantigen-immune effector cell engaging antibodies and uses thereof |
| WO2025072450A1 (en) | 2023-09-26 | 2025-04-03 | Werewolf Therapeutics, Inc. | Enhanced adoptive cell therapy |
| CN119265218A (zh) * | 2023-11-24 | 2025-01-07 | 福建医科大学附属第二医院 | 一种MuSK抗体检测方法及相应产品 |
| WO2025199276A1 (en) * | 2024-03-20 | 2025-09-25 | Cabaletta Bio, Inc. | Methods and compositions for treating autoimmune diseases |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| GB9125768D0 (en) | 1991-12-04 | 1992-02-05 | Hale Geoffrey | Therapeutic method |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US5814478A (en) * | 1995-12-15 | 1998-09-29 | Regeneron Pharmaceuticals, Inc. | Tyrosine kinase receptors and ligands |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| HK1052372A1 (zh) | 2000-02-24 | 2003-09-11 | Xcyte Therapies, Inc. | 细胞的同步刺激和富集 |
| US20050227301A1 (en) * | 2003-01-10 | 2005-10-13 | Polgen | Cell cycle progression proteins |
| JP2014509841A (ja) * | 2011-01-18 | 2014-04-24 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 癌を治療するための組成物および方法 |
| WO2013151664A1 (en) * | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
| BR112015026019A2 (pt) * | 2013-04-11 | 2017-07-25 | Brigham & Womens Hospital Inc | métodos e composições de tratamento de doenças autoimunes |
| WO2015039015A2 (en) | 2013-09-13 | 2015-03-19 | New York University | Methods for treating muscle specific receptor kinase myasthenia gravis |
| EP3166968B1 (en) | 2014-05-02 | 2021-09-22 | The Trustees of the University of Pennsylvania | Compositions and methods of chimeric autoantibody receptor t cells |
| AU2015292744C1 (en) | 2014-07-21 | 2021-01-21 | Novartis Ag | Treatment of cancer using humanized anti-BCMA chimeric antigen receptor |
| WO2018127585A1 (en) | 2017-01-06 | 2018-07-12 | Txcell | Monospecific regulatory t cell population with cytotoxicity for b cells |
-
2019
- 2019-06-04 MX MX2020013239A patent/MX421685B/es unknown
- 2019-06-04 AU AU2019282634A patent/AU2019282634A1/en not_active Abandoned
- 2019-06-04 CA CA3101028A patent/CA3101028A1/en active Pending
- 2019-06-04 US US16/431,402 patent/US11905321B2/en active Active
- 2019-06-04 KR KR1020207035654A patent/KR20210018833A/ko not_active Ceased
- 2019-06-04 JP JP2020567760A patent/JP7561036B2/ja active Active
- 2019-06-04 CN CN201980046782.3A patent/CN112423793A/zh active Pending
- 2019-06-04 WO PCT/US2019/035409 patent/WO2019236593A1/en not_active Ceased
- 2019-06-04 EP EP19815234.0A patent/EP3801642A4/en active Pending
-
2024
- 2024-01-19 US US18/417,630 patent/US12637501B2/en active Active
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