JP2021526528A - スフィンゴシン/スフィンゴイド塩基の製造 - Google Patents

スフィンゴシン/スフィンゴイド塩基の製造 Download PDF

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Publication number
JP2021526528A
JP2021526528A JP2020567066A JP2020567066A JP2021526528A JP 2021526528 A JP2021526528 A JP 2021526528A JP 2020567066 A JP2020567066 A JP 2020567066A JP 2020567066 A JP2020567066 A JP 2020567066A JP 2021526528 A JP2021526528 A JP 2021526528A
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JP
Japan
Prior art keywords
general formula
compound
alkyl
substituted
protecting group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2020567066A
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English (en)
Japanese (ja)
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JP2021526528A5 (https=
JPWO2019238970A5 (https=
Inventor
ジュラ デカニー,
ジュラ デカニー,
フェレンス ホルヴァス,
フェレンス ホルヴァス,
ジョルジー オストロヴスキ,
ジョルジー オストロヴスキ,
ジョージ サントス,
ジョージ サントス,
ピロスカ コヴァクス−ペンゼス,
ピロスカ コヴァクス−ペンゼス,
アンドラス ナギ,
アンドラス ナギ,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carbocode SA
Original Assignee
Carbocode SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carbocode SA filed Critical Carbocode SA
Publication of JP2021526528A publication Critical patent/JP2021526528A/ja
Publication of JP2021526528A5 publication Critical patent/JP2021526528A5/ja
Publication of JPWO2019238970A5 publication Critical patent/JPWO2019238970A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/24Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020567066A 2018-06-15 2019-06-14 スフィンゴシン/スフィンゴイド塩基の製造 Withdrawn JP2021526528A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102018114379 2018-06-15
DE102018114379.6 2018-06-15
PCT/EP2019/065785 WO2019238970A1 (en) 2018-06-15 2019-06-14 Sphingosine/sphingoid base production

Publications (3)

Publication Number Publication Date
JP2021526528A true JP2021526528A (ja) 2021-10-07
JP2021526528A5 JP2021526528A5 (https=) 2022-02-08
JPWO2019238970A5 JPWO2019238970A5 (https=) 2022-02-08

Family

ID=67145768

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020567066A Withdrawn JP2021526528A (ja) 2018-06-15 2019-06-14 スフィンゴシン/スフィンゴイド塩基の製造

Country Status (7)

Country Link
US (1) US12054462B2 (https=)
EP (1) EP3807244B1 (https=)
JP (1) JP2021526528A (https=)
KR (1) KR20210021371A (https=)
CN (1) CN112368261B (https=)
CA (1) CA3101413A1 (https=)
WO (1) WO2019238970A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11820789B2 (en) * 2018-06-15 2023-11-21 Carbocode S.A. Glycosylated sphingoid bases and production thereof
EP4281435A1 (en) 2021-01-25 2023-11-29 Carbocode S.A. Method for the production of d-erythro-sphingosine and analogs thereof
CN116964029A (zh) * 2021-01-25 2023-10-27 碳码股份公司 D-赤式-鞘氨醇及其类似物的产生方法
WO2023099478A1 (en) 2021-12-02 2023-06-08 Carbocode S.A Method for the production of sphingolipids
JP2025507452A (ja) 2022-02-21 2025-03-18 カタヤ、バイオ(シャンハイ)、カンパニー、リミテッド スフィンゴ脂質の製造
WO2024246759A1 (en) 2023-05-29 2024-12-05 Cataya Bio (Shanghai) Co., Ltd. Lipid blends
WO2026033360A1 (en) 2024-08-05 2026-02-12 Carbocode S.A. Method for the production of sphingolipids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO536797A0 (en) 1997-02-28 1997-03-20 Alchemia Pty Ltd Protected aminosugars
FR2823117A1 (fr) * 2000-11-14 2002-10-11 Pharmascience Lab Composition pharmaceutique ou cosmetique ainsi que l'utilisation d'au moins un compose actif pour inhiber la migration des cellules de langerhans
BR0205172A (pt) * 2001-12-20 2004-06-29 Cosmoferm Bv Processo para a sìntese de esfingosina
ATE510815T1 (de) 2003-02-26 2011-06-15 Cosmoferm Bv Ein verfahren zur herstellung von sphingosin
EP1767644B1 (en) 2005-09-22 2010-01-13 Cosmoferm B.V. Microbial strains producing sphingosine

Also Published As

Publication number Publication date
WO2019238970A1 (en) 2019-12-19
US20210253536A1 (en) 2021-08-19
CA3101413A1 (en) 2019-12-19
CN112368261B (zh) 2024-02-20
EP3807244A1 (en) 2021-04-21
US12054462B2 (en) 2024-08-06
EP3807244B1 (en) 2024-03-13
CN112368261A (zh) 2021-02-12
KR20210021371A (ko) 2021-02-25

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