CN112368261B - 鞘氨醇/鞘氨醇碱生产 - Google Patents
鞘氨醇/鞘氨醇碱生产 Download PDFInfo
- Publication number
- CN112368261B CN112368261B CN201980040317.9A CN201980040317A CN112368261B CN 112368261 B CN112368261 B CN 112368261B CN 201980040317 A CN201980040317 A CN 201980040317A CN 112368261 B CN112368261 B CN 112368261B
- Authority
- CN
- China
- Prior art keywords
- group
- general formula
- sphingosine
- compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/24—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102018114379 | 2018-06-15 | ||
| DE102018114379.6 | 2018-06-15 | ||
| PCT/EP2019/065785 WO2019238970A1 (en) | 2018-06-15 | 2019-06-14 | Sphingosine/sphingoid base production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112368261A CN112368261A (zh) | 2021-02-12 |
| CN112368261B true CN112368261B (zh) | 2024-02-20 |
Family
ID=67145768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980040317.9A Active CN112368261B (zh) | 2018-06-15 | 2019-06-14 | 鞘氨醇/鞘氨醇碱生产 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12054462B2 (https=) |
| EP (1) | EP3807244B1 (https=) |
| JP (1) | JP2021526528A (https=) |
| KR (1) | KR20210021371A (https=) |
| CN (1) | CN112368261B (https=) |
| CA (1) | CA3101413A1 (https=) |
| WO (1) | WO2019238970A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11820789B2 (en) * | 2018-06-15 | 2023-11-21 | Carbocode S.A. | Glycosylated sphingoid bases and production thereof |
| EP4281435A1 (en) | 2021-01-25 | 2023-11-29 | Carbocode S.A. | Method for the production of d-erythro-sphingosine and analogs thereof |
| CN116964029A (zh) * | 2021-01-25 | 2023-10-27 | 碳码股份公司 | D-赤式-鞘氨醇及其类似物的产生方法 |
| WO2023099478A1 (en) | 2021-12-02 | 2023-06-08 | Carbocode S.A | Method for the production of sphingolipids |
| JP2025507452A (ja) | 2022-02-21 | 2025-03-18 | カタヤ、バイオ（シャンハイ）、カンパニー、リミテッド | スフィンゴ脂質の製造 |
| WO2024246759A1 (en) | 2023-05-29 | 2024-12-05 | Cataya Bio (Shanghai) Co., Ltd. | Lipid blends |
| WO2026033360A1 (en) | 2024-08-05 | 2026-02-12 | Carbocode S.A. | Method for the production of sphingolipids |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1486179A (zh) * | 2000-11-14 | 2004-03-31 | 实验室发展科学公司 | 药物或化妆品组合物及抑制朗格汉斯细胞迁移的pkc抑制剂和mmp抑制剂的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO536797A0 (en) | 1997-02-28 | 1997-03-20 | Alchemia Pty Ltd | Protected aminosugars |
| BR0205172A (pt) * | 2001-12-20 | 2004-06-29 | Cosmoferm Bv | Processo para a sìntese de esfingosina |
| ATE510815T1 (de) | 2003-02-26 | 2011-06-15 | Cosmoferm Bv | Ein verfahren zur herstellung von sphingosin |
| EP1767644B1 (en) | 2005-09-22 | 2010-01-13 | Cosmoferm B.V. | Microbial strains producing sphingosine |
-
2019
- 2019-06-14 JP JP2020567066A patent/JP2021526528A/ja not_active Withdrawn
- 2019-06-14 CA CA3101413A patent/CA3101413A1/en not_active Abandoned
- 2019-06-14 EP EP19735495.4A patent/EP3807244B1/en active Active
- 2019-06-14 CN CN201980040317.9A patent/CN112368261B/zh active Active
- 2019-06-14 WO PCT/EP2019/065785 patent/WO2019238970A1/en not_active Ceased
- 2019-06-14 US US17/251,978 patent/US12054462B2/en active Active
- 2019-06-14 KR KR1020217001110A patent/KR20210021371A/ko not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1486179A (zh) * | 2000-11-14 | 2004-03-31 | 实验室发展科学公司 | 药物或化妆品组合物及抑制朗格汉斯细胞迁移的pkc抑制剂和mmp抑制剂的应用 |
Non-Patent Citations (7)
| Title |
|---|
| A novel amino protecting group: DTPM;Laurent Bornaghi等;Tetrahedron Letters;第42卷;摘要，第3131页Scheme4、Scheme5 * |
| A rapid synthesis of sphingosine from phytosphingosine;Sankar, Arumugam等;《Carbohydrate Research》;20180630;第463卷;图1、Scheme2 * |
| A rapid synthesis of sphingosine from phytosphingosine;Sankar, Arumugam等;Carbohydrate Research;第463卷;第2页图1，第3页Scheme2 * |
| Protected Sphingosine from Phytosphingosine as an Efficient Acceptor in Glycosylation Reaction;Luigi Panza等;《Org. Lett.》;20140115;第16卷;第953页Scheme1-2 * |
| Sankar, Arumugam等.A rapid synthesis of sphingosine from phytosphingosine.《Carbohydrate Research》.2018,第463卷图1、Scheme2. * |
| 一系列鞘糖脂类化合物的合成;刘运鹏;《工程科技Ⅰ辑》;20070331;正文第41-42页 * |
| 一系列鞘糖脂类化合物的合成;刘运鹏;工程科技Ⅰ辑;正文第41-42页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019238970A1 (en) | 2019-12-19 |
| US20210253536A1 (en) | 2021-08-19 |
| CA3101413A1 (en) | 2019-12-19 |
| EP3807244A1 (en) | 2021-04-21 |
| US12054462B2 (en) | 2024-08-06 |
| EP3807244B1 (en) | 2024-03-13 |
| CN112368261A (zh) | 2021-02-12 |
| KR20210021371A (ko) | 2021-02-25 |
| JP2021526528A (ja) | 2021-10-07 |
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Legal Events
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |