JP2021525771A5 - - Google Patents
Info
- Publication number
- JP2021525771A5 JP2021525771A5 JP2020567199A JP2020567199A JP2021525771A5 JP 2021525771 A5 JP2021525771 A5 JP 2021525771A5 JP 2020567199 A JP2020567199 A JP 2020567199A JP 2020567199 A JP2020567199 A JP 2020567199A JP 2021525771 A5 JP2021525771 A5 JP 2021525771A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- compound
- pharmaceutically acceptable
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862680324P | 2018-06-04 | 2018-06-04 | |
| US62/680,324 | 2018-06-04 | ||
| PCT/US2019/035247 WO2019236496A1 (en) | 2018-06-04 | 2019-06-03 | Pyrimidine compounds containing acidic groups useful to treat diseases connected to the modulation of tlr7 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525771A JP2021525771A (ja) | 2021-09-27 |
| JP2021525771A5 true JP2021525771A5 (enExample) | 2022-06-06 |
| JP7351859B2 JP7351859B2 (ja) | 2023-09-27 |
Family
ID=66913097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567199A Active JP7351859B2 (ja) | 2018-06-04 | 2019-06-03 | Tlr7の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10857153B2 (enExample) |
| EP (1) | EP3802519A1 (enExample) |
| JP (1) | JP7351859B2 (enExample) |
| CN (1) | CN112513031A (enExample) |
| AR (1) | AR114910A1 (enExample) |
| TW (1) | TW202003475A (enExample) |
| WO (1) | WO2019236496A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10786502B2 (en) | 2016-12-05 | 2020-09-29 | Apros Therapeutics, Inc. | Substituted pyrimidines containing acidic groups as TLR7 modulators |
| TW202003475A (zh) | 2018-06-04 | 2020-01-16 | 美商亞博創新醫藥有限公司 | 含酸性基團之嘧啶化合物 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73534A (en) | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| DE69720965T2 (de) | 1996-02-13 | 2004-02-05 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
| ES2232871T3 (es) | 1996-07-03 | 2005-06-01 | Sumitomo Pharmaceuticals Company, Limited | Nuevos derivados de purina. |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| CA2280930C (en) | 1997-02-12 | 2010-04-06 | The Regents Of The University Of Michigan | Protein markers for lung cancer and use thereof |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| DE69817393T2 (de) | 1997-11-28 | 2004-06-17 | Sumitomo Pharmaceuticals Co., Ltd. | Neue heterozyklische verbindungen |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| PT1154774E (pt) | 1999-02-10 | 2005-10-31 | Astrazeneca Ab | Derivados de quinazolina como inibidores de angiogenese |
| KR100881105B1 (ko) | 1999-11-05 | 2009-02-02 | 아스트라제네카 아베 | Vegf 억제제로서의 퀴나졸린 유도체 |
| JP3663382B2 (ja) | 2000-02-15 | 2005-06-22 | スージェン・インコーポレーテッド | ピロール置換2−インドリノン蛋白質キナーゼ阻害剤 |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| UA73993C2 (uk) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хіназолінові похідні для лікування пухлин та фармацевтична композиція |
| MXPA02012903A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como inhibidores de angiogenesis. |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| US8138172B2 (en) | 2006-07-05 | 2012-03-20 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of TLR7 |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| AU2010250923A1 (en) | 2009-05-21 | 2011-11-17 | Astrazeneca Ab | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| AU2011295853A1 (en) | 2010-09-01 | 2013-04-04 | Irm Llc | Adsorption of immunopotentiators to insoluble metal salts |
| WO2012066336A1 (en) | 2010-11-19 | 2012-05-24 | Astrazeneca Ab | Benzylamine compounds as toll -like receptor 7 agonists |
| JP6184423B2 (ja) * | 2012-05-18 | 2017-08-23 | 大日本住友製薬株式会社 | カルボン酸化合物 |
| SG11201506639XA (en) | 2013-02-21 | 2015-09-29 | Janssen Sciences Ireland Uc | 2-aminopyrimidine derivatives for the treatment of viral infections |
| JP7071392B2 (ja) | 2016-12-05 | 2022-05-18 | アプロス セラピューティクス, インコーポレイテッド | 酸性基を含有するピリミジン化合物 |
| US10786502B2 (en) | 2016-12-05 | 2020-09-29 | Apros Therapeutics, Inc. | Substituted pyrimidines containing acidic groups as TLR7 modulators |
| TW202003475A (zh) | 2018-06-04 | 2020-01-16 | 美商亞博創新醫藥有限公司 | 含酸性基團之嘧啶化合物 |
-
2019
- 2019-06-03 TW TW108119118A patent/TW202003475A/zh unknown
- 2019-06-03 CN CN201980050020.0A patent/CN112513031A/zh active Pending
- 2019-06-03 AR ARP190101499A patent/AR114910A1/es unknown
- 2019-06-03 US US16/429,104 patent/US10857153B2/en not_active Expired - Fee Related
- 2019-06-03 EP EP19731568.2A patent/EP3802519A1/en not_active Withdrawn
- 2019-06-03 JP JP2020567199A patent/JP7351859B2/ja active Active
- 2019-06-03 WO PCT/US2019/035247 patent/WO2019236496A1/en not_active Ceased
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