JP2021524442A5 - - Google Patents
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- Publication number
- JP2021524442A5 JP2021524442A5 JP2020564437A JP2020564437A JP2021524442A5 JP 2021524442 A5 JP2021524442 A5 JP 2021524442A5 JP 2020564437 A JP2020564437 A JP 2020564437A JP 2020564437 A JP2020564437 A JP 2020564437A JP 2021524442 A5 JP2021524442 A5 JP 2021524442A5
- Authority
- JP
- Japan
- Prior art keywords
- chewing gum
- tableted
- tableted chewing
- sugar alcohol
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims 31
- 229940112822 chewing gum Drugs 0.000 claims 27
- 235000015218 chewing gum Nutrition 0.000 claims 27
- 150000005846 sugar alcohols Chemical class 0.000 claims 15
- 239000004386 Erythritol Substances 0.000 claims 4
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 4
- 235000019414 erythritol Nutrition 0.000 claims 4
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 4
- 229940009714 erythritol Drugs 0.000 claims 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 4
- 239000000811 xylitol Substances 0.000 claims 4
- 235000010447 xylitol Nutrition 0.000 claims 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 4
- 229960002675 xylitol Drugs 0.000 claims 4
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 239000000905 isomalt Substances 0.000 claims 3
- 235000010439 isomalt Nutrition 0.000 claims 3
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 claims 3
- 235000010449 maltitol Nutrition 0.000 claims 3
- 239000000845 maltitol Substances 0.000 claims 3
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 3
- 229940035436 maltitol Drugs 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 2
- 229920001971 elastomer Polymers 0.000 claims 2
- 239000000806 elastomer Substances 0.000 claims 2
- 239000006191 orally-disintegrating tablet Substances 0.000 claims 2
- 239000004034 viscosity adjusting agent Substances 0.000 claims 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 229920000084 Gum arabic Polymers 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 241000978776 Senegalia senegal Species 0.000 claims 1
- 235000010489 acacia gum Nutrition 0.000 claims 1
- 239000000205 acacia gum Substances 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 229940113118 carrageenan Drugs 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000000832 lactitol Substances 0.000 claims 1
- 235000010448 lactitol Nutrition 0.000 claims 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims 1
- 229960003451 lactitol Drugs 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 229960000292 pectin Drugs 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 235000010413 sodium alginate Nutrition 0.000 claims 1
- 239000000661 sodium alginate Substances 0.000 claims 1
- 229940005550 sodium alginate Drugs 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/982,772 | 2018-05-17 | ||
| US15/982,772 US11096895B2 (en) | 2018-05-17 | 2018-05-17 | Oral tablet suitable for active pharmaceutical ingredients |
| US15/986,362 | 2018-05-22 | ||
| US15/986,362 US11090263B2 (en) | 2018-05-22 | 2018-05-22 | Tableted chewing gum suitable for active pharmaceutical ingredients |
| PCT/DK2019/050157 WO2019219147A1 (en) | 2018-05-17 | 2019-05-15 | A tableted chewing gum suitable for active pharmaceutical ingredients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021524442A JP2021524442A (ja) | 2021-09-13 |
| JP2021524442A5 true JP2021524442A5 (https=) | 2021-10-21 |
| JP7214755B2 JP7214755B2 (ja) | 2023-01-30 |
Family
ID=66820994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564437A Active JP7214755B2 (ja) | 2018-05-17 | 2019-05-15 | 医薬品活性成分に適した錠剤化チューインガム |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3787604B1 (https=) |
| JP (1) | JP7214755B2 (https=) |
| KR (1) | KR102697867B1 (https=) |
| CN (1) | CN112118831B (https=) |
| AU (1) | AU2019268497B2 (https=) |
| BR (1) | BR112020022379A2 (https=) |
| CA (1) | CA3097953C (https=) |
| ES (1) | ES2951848T3 (https=) |
| MX (1) | MX2020012265A (https=) |
| RU (1) | RU2770035C1 (https=) |
| WO (1) | WO2019219147A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11096894B2 (en) | 2018-05-17 | 2021-08-24 | Fertin Pharma A/S | Oral tablet for induced saliva generation |
| US10933017B2 (en) | 2019-03-01 | 2021-03-02 | Nordiccan A/S | Tableted cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11253473B2 (en) | 2019-03-01 | 2022-02-22 | Nordiccan A/S | Method of producing tableted cannabinoid chewing gum |
| US11471405B2 (en) | 2019-03-01 | 2022-10-18 | Nordiccan A/S | Tableted chewing gum with enhanced delivery of cannabinoids |
| US11793230B2 (en) | 2019-12-09 | 2023-10-24 | Nicoventures Trading Limited | Oral products with improved binding of active ingredients |
| US12439952B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Moist oral compositions |
| WO2021116842A1 (en) * | 2019-12-09 | 2021-06-17 | Nicoventures Trading Limited | Oral products with controlled release |
| US12520867B2 (en) | 2019-12-09 | 2026-01-13 | Nicoventures Trading Limited | Buffered oral compositions |
| US11826462B2 (en) | 2019-12-09 | 2023-11-28 | Nicoventures Trading Limited | Oral product with sustained flavor release |
| US12433321B2 (en) | 2019-12-09 | 2025-10-07 | Nicoventures Trading Limited | Oral composition with beet material |
| US12310959B2 (en) | 2019-12-09 | 2025-05-27 | Nicoventures Trading Limited | Oral compositions with reduced water content |
| US11969502B2 (en) | 2019-12-09 | 2024-04-30 | Nicoventures Trading Limited | Oral products |
| US11617744B2 (en) | 2019-12-09 | 2023-04-04 | Nico Ventures Trading Limited | Moist oral compositions |
| US12439949B2 (en) | 2019-12-09 | 2025-10-14 | Nicoventures Trading Limited | Oral compositions with reduced water activity |
| US11872231B2 (en) | 2019-12-09 | 2024-01-16 | Nicoventures Trading Limited | Moist oral product comprising an active ingredient |
| EP4146166A1 (en) * | 2020-05-08 | 2023-03-15 | Fertin Pharma A/S | Mouthwash for oral care benefits |
| MX2023015529A (es) | 2021-06-25 | 2024-03-05 | Nicoventures Trading Ltd | Productos orales y metodo de fabricacion. |
| DK202330231A1 (en) * | 2023-09-27 | 2025-04-10 | Fertin Pharma As | Cannabidiol for alleviating xerostomia |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3070510A (en) | 1959-11-03 | 1962-12-25 | Procter & Gamble | Dentifrice containing resinous cleaning agents |
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US3862307A (en) | 1973-04-09 | 1975-01-21 | Procter & Gamble | Dentifrices containing a cationic therapeutic agent and improved silica abrasive |
| US4340583A (en) | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4997654A (en) * | 1989-08-14 | 1991-03-05 | Warner-Lambert Company | Method for increasing salivation for xerostomia patients |
| JP3122141B2 (ja) * | 1994-01-31 | 2001-01-09 | 山之内製薬株式会社 | 口腔内溶解型圧縮成型物及びその製造法 |
| US5576014A (en) * | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
| US6024981A (en) * | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| WO2000025598A1 (en) | 1998-11-03 | 2000-05-11 | Dandy A/S | Sucrose fatty acid esters for use as increased release of active ingredients |
| US6350480B1 (en) * | 1999-12-30 | 2002-02-26 | Wm. Wrigley Jr. Company | Chewing gum product including a hydrophilic gum base and method of producing |
| JP2004520389A (ja) * | 2001-02-08 | 2004-07-08 | ファルマシア・コーポレーション | 性的不全の治療のための早期効果発現薬剤 |
| SE0102197D0 (sv) * | 2001-06-20 | 2001-06-20 | Pharmacia Ab | New product and use and manufacture thereof |
| WO2006063189A2 (en) * | 2004-12-10 | 2006-06-15 | Novartis Ag | Multi-layered chewing gum tablet with quick disintegration layer |
| RU2391856C2 (ru) * | 2005-12-16 | 2010-06-20 | Вм. Ригли Дж. Компани | Жевательная резинка в оболочке |
| CN101563069B (zh) * | 2006-08-04 | 2012-07-11 | 爱的发 | 多层口服崩解片 |
| JP5766899B2 (ja) * | 2007-04-11 | 2015-08-19 | ニプロ株式会社 | 口腔内崩壊剤及びその製造方法 |
| WO2009080023A1 (en) * | 2007-12-20 | 2009-07-02 | Fertin Pharma A/S | Compressed chewing gum comprising peptide |
| US9511021B2 (en) * | 2008-05-21 | 2016-12-06 | Novartis, A.G. | Tablettable chewing gums |
| WO2010019689A2 (en) * | 2008-08-14 | 2010-02-18 | Wm. Wrigley Jr. Company | Confectionery products providing an increased hydration sensation |
| EP2793849A1 (en) * | 2011-12-22 | 2014-10-29 | Fertin Pharma A/S | Method of releasing nicotine from chewing gum |
| WO2013171164A1 (en) * | 2012-05-14 | 2013-11-21 | EJP Pharmaceutical ApS | Compositions and formulations for the treatment of halitosis |
| CA2978517A1 (en) * | 2014-03-04 | 2015-09-11 | Eastgate Pharmaceuticals Inc. | Pharmaceutical composition for transmucosal delivery and methods for treating diabetes in a subject in need thereof |
| FR3023128B1 (fr) * | 2014-07-01 | 2017-11-10 | Roquette Freres | Nouvelle composition edulcorante |
| BR112019007798B1 (pt) * | 2016-11-18 | 2023-12-19 | Fertin Pharma A/S | Comprimido com veículo de liberação oral |
| CN110087634A (zh) * | 2016-11-18 | 2019-08-02 | 费丁制药联合股份有限公司 | 提供口腔护理有益效果的方法 |
-
2019
- 2019-05-15 BR BR112020022379-4A patent/BR112020022379A2/pt unknown
- 2019-05-15 AU AU2019268497A patent/AU2019268497B2/en active Active
- 2019-05-15 CN CN201980032268.4A patent/CN112118831B/zh active Active
- 2019-05-15 CA CA3097953A patent/CA3097953C/en active Active
- 2019-05-15 EP EP19729615.5A patent/EP3787604B1/en active Active
- 2019-05-15 KR KR1020207031894A patent/KR102697867B1/ko active Active
- 2019-05-15 JP JP2020564437A patent/JP7214755B2/ja active Active
- 2019-05-15 RU RU2020141413A patent/RU2770035C1/ru active
- 2019-05-15 WO PCT/DK2019/050157 patent/WO2019219147A1/en not_active Ceased
- 2019-05-15 MX MX2020012265A patent/MX2020012265A/es unknown
- 2019-05-15 ES ES19729615T patent/ES2951848T3/es active Active
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