JP2021523151A - 負の表面電荷を有するマイクロ粒子及びナノ粒子 - Google Patents

負の表面電荷を有するマイクロ粒子及びナノ粒子 Download PDF

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Publication number
JP2021523151A
JP2021523151A JP2020562668A JP2020562668A JP2021523151A JP 2021523151 A JP2021523151 A JP 2021523151A JP 2020562668 A JP2020562668 A JP 2020562668A JP 2020562668 A JP2020562668 A JP 2020562668A JP 2021523151 A JP2021523151 A JP 2021523151A
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Prior art keywords
solvent
nanoparticles
microparticles
plga
solution
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Japanese (ja)
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JP2021523151A5 (https=
JPWO2019217780A5 (https=
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ウー、ビン
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ホスホレックス、インコーポレイテッド
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=68468426&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2021523151(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ホスホレックス、インコーポレイテッド filed Critical ホスホレックス、インコーポレイテッド
Publication of JP2021523151A publication Critical patent/JP2021523151A/ja
Publication of JP2021523151A5 publication Critical patent/JP2021523151A5/ja
Publication of JPWO2019217780A5 publication Critical patent/JPWO2019217780A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
JP2020562668A 2018-05-11 2019-05-10 負の表面電荷を有するマイクロ粒子及びナノ粒子 Pending JP2021523151A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670204P 2018-05-11 2018-05-11
US62/670,204 2018-05-11
PCT/US2019/031659 WO2019217780A1 (en) 2018-05-11 2019-05-10 Microparticles and nanoparticles having negative surface charges

Publications (3)

Publication Number Publication Date
JP2021523151A true JP2021523151A (ja) 2021-09-02
JP2021523151A5 JP2021523151A5 (https=) 2022-05-17
JPWO2019217780A5 JPWO2019217780A5 (https=) 2022-05-17

Family

ID=68468426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020562668A Pending JP2021523151A (ja) 2018-05-11 2019-05-10 負の表面電荷を有するマイクロ粒子及びナノ粒子

Country Status (5)

Country Link
US (1) US20210169819A1 (https=)
EP (1) EP3814272A4 (https=)
JP (1) JP2021523151A (https=)
CA (1) CA3098873A1 (https=)
WO (1) WO2019217780A1 (https=)

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AU2021239983A1 (en) * 2020-03-18 2022-09-22 Flow Pharma, Inc. Injectable formulation of poly(lactic-co-glycolic (PLGA)) microspheres encapsulating siltuximab
JP2023544419A (ja) 2020-10-05 2023-10-23 サイトダイム，インコーポレイテッド Ｓｉｇｌｅｃ結合剤の医薬組成物
CN115382476B (zh) * 2022-07-26 2024-10-22 华东师范大学 一种超小粒径聚合物纳米颗粒的制备方法
US20260053750A1 (en) * 2022-08-17 2026-02-26 Matthew Owen Inhalable compositions of cdk9 inhibitors
CN115969796B (zh) * 2022-12-06 2024-07-09 苏州大学 一种jak抑制剂长效微球及其制备方法与应用
WO2025250539A1 (en) * 2024-05-29 2025-12-04 Cytodigm, Inc. Pharmaceutical composition comprising sialic acid for treating diseases related to the lung
CN119033092B (zh) * 2024-10-30 2024-12-24 恢春丹生物科技(海南)有限公司 一种蛹虫草灵芝孢子粉复合制剂及其应用

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Publication number Publication date
WO2019217780A1 (en) 2019-11-14
CA3098873A1 (en) 2019-11-14
EP3814272A4 (en) 2022-03-02
US20210169819A1 (en) 2021-06-10
EP3814272A1 (en) 2021-05-05

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