AU5732296A - Method for inhibiting the binding of selectins to sialyl-lew ises - Google Patents

Method for inhibiting the binding of selectins to sialyl-lew ises

Info

Publication number
AU5732296A
AU5732296A AU57322/96A AU5732296A AU5732296A AU 5732296 A AU5732296 A AU 5732296A AU 57322/96 A AU57322/96 A AU 57322/96A AU 5732296 A AU5732296 A AU 5732296A AU 5732296 A AU5732296 A AU 5732296A
Authority
AU
Australia
Prior art keywords
ises
lew
selectins
sialyl
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU57322/96A
Inventor
Pamela J Beck
Robert J. Bjercke
Huong M. Bui
Brian Dupre
Karin M. Keller
Phi Nga Thi Kint
Timothy P Kogan
Robert V. Market
Ian L Scott
Sidney J. Sherwood
Ronald G Tilton
Edward T. Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Encysive Pharmaceuticals Inc
Original Assignee
Texas Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texas Biotechnology Corp filed Critical Texas Biotechnology Corp
Publication of AU5732296A publication Critical patent/AU5732296A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
AU57322/96A 1995-05-08 1996-05-06 Method for inhibiting the binding of selectins to sialyl-lew ises Abandoned AU5732296A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43612695A 1995-05-08 1995-05-08
US436126 1995-05-08
PCT/US1996/006453 WO1996035418A1 (en) 1995-05-08 1996-05-06 Method for inhibiting the binding of selectins to sialyl-lewises

Publications (1)

Publication Number Publication Date
AU5732296A true AU5732296A (en) 1996-11-29

Family

ID=23731211

Family Applications (1)

Application Number Title Priority Date Filing Date
AU57322/96A Abandoned AU5732296A (en) 1995-05-08 1996-05-06 Method for inhibiting the binding of selectins to sialyl-lew ises

Country Status (2)

Country Link
AU (1) AU5732296A (en)
WO (1) WO1996035418A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2281684C (en) 1997-02-28 2006-08-29 The Regents Of The University Of California Inhibition of cell-cell binding by lipid assemblies
BRPI0510221A (en) 2004-05-14 2007-10-23 Emisphere Tech Inc aryl ketone compound, composition, unit dosage form, use of the composition and method for preparing a composition
EP2928500B1 (en) 2012-12-04 2019-03-06 Phosphorex Inc. Microparticles and nanoparticles having negative surface charges
CA2903718A1 (en) 2013-03-13 2014-10-02 Cour Pharmaceuticals Development Co., Inc. Immune-modifying particles for the treatment of inflammation
WO2019217780A1 (en) 2018-05-11 2019-11-14 Phosphorex, Inc. Microparticles and nanoparticles having negative surface charges

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4009197A (en) * 1967-01-13 1977-02-22 Syntex Corporation 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid

Also Published As

Publication number Publication date
WO1996035418A1 (en) 1996-11-14

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