JP2021523101A5 - - Google Patents

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Publication number
JP2021523101A5
JP2021523101A5 JP2020560761A JP2020560761A JP2021523101A5 JP 2021523101 A5 JP2021523101 A5 JP 2021523101A5 JP 2020560761 A JP2020560761 A JP 2020560761A JP 2020560761 A JP2020560761 A JP 2020560761A JP 2021523101 A5 JP2021523101 A5 JP 2021523101A5
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JP
Japan
Prior art keywords
amino acid
domain
tag
polypeptide
terminus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020560761A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021523101A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/031379 external-priority patent/WO2019217587A1/en
Publication of JP2021523101A publication Critical patent/JP2021523101A/ja
Publication of JP2021523101A5 publication Critical patent/JP2021523101A5/ja
Priority to JP2023191593A priority Critical patent/JP7785734B2/ja
Priority to JP2025219116A priority patent/JP2026035775A/ja
Pending legal-status Critical Current

Links

JP2020560761A 2018-05-08 2019-05-08 切断可能なｃ末端電荷対タグを有する二重特異性抗体 Pending JP2021523101A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023191593A JP7785734B2 (ja) 2018-05-08 2023-11-09 切断可能なｃ末端電荷対タグを有する二重特異性抗体
JP2025219116A JP2026035775A (ja) 2018-05-08 2025-12-02 切断可能なｃ末端電荷対タグを有する二重特異性抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862668626P 2018-05-08 2018-05-08
US62/668,626 2018-05-08
PCT/US2019/031379 WO2019217587A1 (en) 2018-05-08 2019-05-08 Bispecific antibodies with cleavable c-terminal charge-paired tags

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023191593A Division JP7785734B2 (ja) 2018-05-08 2023-11-09 切断可能なｃ末端電荷対タグを有する二重特異性抗体

Publications (2)

Publication Number Publication Date
JP2021523101A JP2021523101A (ja) 2021-09-02
JP2021523101A5 true JP2021523101A5 (https=) 2022-05-16

Family

ID=66676901

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020560761A Pending JP2021523101A (ja) 2018-05-08 2019-05-08 切断可能なｃ末端電荷対タグを有する二重特異性抗体
JP2023191593A Active JP7785734B2 (ja) 2018-05-08 2023-11-09 切断可能なｃ末端電荷対タグを有する二重特異性抗体
JP2025219116A Pending JP2026035775A (ja) 2018-05-08 2025-12-02 切断可能なｃ末端電荷対タグを有する二重特異性抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023191593A Active JP7785734B2 (ja) 2018-05-08 2023-11-09 切断可能なｃ末端電荷対タグを有する二重特異性抗体
JP2025219116A Pending JP2026035775A (ja) 2018-05-08 2025-12-02 切断可能なｃ末端電荷対タグを有する二重特異性抗体

Country Status (8)

Country Link
US (2) US12384849B2 (https=)
EP (1) EP3790904A1 (https=)
JP (3) JP2021523101A (https=)
AU (2) AU2019265699B2 (https=)
CA (1) CA3099450A1 (https=)
MA (1) MA52571A (https=)
MX (2) MX2020011844A (https=)
WO (1) WO2019217587A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220363770A1 (en) * 2019-06-28 2022-11-17 Amgen Inc. Anti-cgrp receptor/anti-pac1 receptor bispecific antigen binding proteins
US20250388669A1 (en) * 2022-01-21 2025-12-25 Jieyi Wang Multi-specific antibodies in uses thereof in avidity receptor crosslinking and immune modulation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5932448A (en) 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
US6096871A (en) 1995-04-14 2000-08-01 Genentech, Inc. Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
DE19819846B4 (de) 1998-05-05 2016-11-24 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Multivalente Antikörper-Konstrukte
US7101692B2 (en) * 1999-04-15 2006-09-05 The Regents Of The University Of California Identification of sortase gene
CA2377513A1 (en) 1999-06-25 2001-01-04 Universitat Zurich Hetero-associating coiled-coil peptides
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
WO2004047762A2 (en) * 2002-11-25 2004-06-10 Chiron Corporation Methods for treating cancer using porimin as a target
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
US8703132B2 (en) 2009-06-18 2014-04-22 Hoffmann-La Roche, Inc. Bispecific, tetravalent antigen binding proteins
EP2478013B1 (en) 2009-09-16 2018-10-24 F.Hoffmann-La Roche Ag Coiled coil and/or tether containing protein complexes and uses thereof
MX340696B (es) * 2010-04-30 2016-07-21 Alexion Pharma Inc Anticuerpos anti-c5a y metodos para usar los anticuerpos.
US10851178B2 (en) * 2011-10-10 2020-12-01 Xencor, Inc. Heterodimeric human IgG1 polypeptides with isoelectric point modifications
JO3519B1 (ar) * 2013-01-25 2020-07-05 Amgen Inc تركيبات أجسام مضادة لأجل cdh19 و cd3
US10077299B2 (en) * 2013-04-25 2018-09-18 Abtlas Co., Ltd. Method for refining protein including self-cutting cassette and use thereof
RS61907B1 (sr) 2015-04-06 2021-06-30 Subdomain Llc Polipeptidi koji sadrže de novo vezujući domen i njihova primena
EP3307321A4 (en) 2015-08-26 2019-04-17 Bison Therapeutics Inc. MULTISPECIFIC ANTIBODY PLATFORM AND ASSOCIATED METHODS

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