JP2021523101A5 - - Google Patents
Info
- Publication number
- JP2021523101A5 JP2021523101A5 JP2020560761A JP2020560761A JP2021523101A5 JP 2021523101 A5 JP2021523101 A5 JP 2021523101A5 JP 2020560761 A JP2020560761 A JP 2020560761A JP 2020560761 A JP2020560761 A JP 2020560761A JP 2021523101 A5 JP2021523101 A5 JP 2021523101A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- domain
- tag
- polypeptide
- terminus
- Prior art date
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023191593A JP7785734B2 (ja) | 2018-05-08 | 2023-11-09 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
| JP2025219116A JP2026035775A (ja) | 2018-05-08 | 2025-12-02 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862668626P | 2018-05-08 | 2018-05-08 | |
| US62/668,626 | 2018-05-08 | ||
| PCT/US2019/031379 WO2019217587A1 (en) | 2018-05-08 | 2019-05-08 | Bispecific antibodies with cleavable c-terminal charge-paired tags |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023191593A Division JP7785734B2 (ja) | 2018-05-08 | 2023-11-09 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523101A JP2021523101A (ja) | 2021-09-02 |
| JP2021523101A5 true JP2021523101A5 (https=) | 2022-05-16 |
| JPWO2019217587A5 JPWO2019217587A5 (https=) | 2022-05-16 |
Family
ID=66676901
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560761A Pending JP2021523101A (ja) | 2018-05-08 | 2019-05-08 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
| JP2023191593A Active JP7785734B2 (ja) | 2018-05-08 | 2023-11-09 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
| JP2025219116A Pending JP2026035775A (ja) | 2018-05-08 | 2025-12-02 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023191593A Active JP7785734B2 (ja) | 2018-05-08 | 2023-11-09 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
| JP2025219116A Pending JP2026035775A (ja) | 2018-05-08 | 2025-12-02 | 切断可能なｃ末端電荷対タグを有する二重特異性抗体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12384849B2 (https=) |
| EP (1) | EP3790904A1 (https=) |
| JP (3) | JP2021523101A (https=) |
| AU (2) | AU2019265699B2 (https=) |
| CA (1) | CA3099450A1 (https=) |
| MA (1) | MA52571A (https=) |
| MX (2) | MX2020011844A (https=) |
| WO (1) | WO2019217587A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020304671A1 (en) * | 2019-06-28 | 2022-01-20 | Amgen Inc. | Anti-CGRP receptor/anti-PAC1 receptor bispecific antigen binding proteins |
| EP4466020A4 (en) * | 2022-01-21 | 2026-04-15 | Lyvgen Biopharma Holdings Ltd | Multi-specific antibodies and their uses in avidity receptor cross-linking and immune modulation |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5932448A (en) | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| DE19819846B4 (de) | 1998-05-05 | 2016-11-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Multivalente Antikörper-Konstrukte |
| US7101692B2 (en) * | 1999-04-15 | 2006-09-05 | The Regents Of The University Of California | Identification of sortase gene |
| WO2001000814A2 (en) * | 1999-06-25 | 2001-01-04 | Universität Zürich | Hetero-associating coiled-coil peptides and screenign method therefor |
| US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
| US20050214300A1 (en) * | 2002-11-25 | 2005-09-29 | Chiron Corporation | Methods for treating cancer using Porimin as a target |
| EP3050963B1 (en) | 2005-03-31 | 2019-09-18 | Chugai Seiyaku Kabushiki Kaisha | Process for production of polypeptide by regulation of assembly |
| US8703132B2 (en) | 2009-06-18 | 2014-04-22 | Hoffmann-La Roche, Inc. | Bispecific, tetravalent antigen binding proteins |
| KR20120108967A (ko) | 2009-09-16 | 2012-10-05 | 제넨테크, 인크. | 코일드 코일 및/또는 테더 함유 단백질 복합체 및 그의 용도 |
| EP2824111B1 (en) * | 2010-04-30 | 2017-03-22 | Alexion Pharmaceuticals, Inc. | Anti-C5A Antibodies and Methods for Using the Antibodies |
| US10851178B2 (en) * | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| JO3519B1 (ar) * | 2013-01-25 | 2020-07-05 | Amgen Inc | تركيبات أجسام مضادة لأجل cdh19 و cd3 |
| SG11201508732PA (en) * | 2013-04-25 | 2015-11-27 | Scripps Korea Antibody Inst | Method for refining protein including self-cutting cassette and use thereof |
| RS61907B1 (sr) | 2015-04-06 | 2021-06-30 | Subdomain Llc | Polipeptidi koji sadrže de novo vezujući domen i njihova primena |
| KR102095096B1 (ko) * | 2015-08-26 | 2020-03-30 | 바이슨 테라퓨틱스 인크. | 다중특이적 항체 플랫폼 및 관련 방법 |
-
2019
- 2019-05-08 MA MA052571A patent/MA52571A/fr unknown
- 2019-05-08 US US17/053,728 patent/US12384849B2/en active Active
- 2019-05-08 EP EP19727555.5A patent/EP3790904A1/en active Pending
- 2019-05-08 WO PCT/US2019/031379 patent/WO2019217587A1/en not_active Ceased
- 2019-05-08 JP JP2020560761A patent/JP2021523101A/ja active Pending
- 2019-05-08 CA CA3099450A patent/CA3099450A1/en active Pending
- 2019-05-08 MX MX2020011844A patent/MX2020011844A/es unknown
- 2019-05-08 AU AU2019265699A patent/AU2019265699B2/en active Active
-
2020
- 2020-11-05 MX MX2025001939A patent/MX2025001939A/es unknown
-
2023
- 2023-11-09 JP JP2023191593A patent/JP7785734B2/ja active Active
-
2025
- 2025-01-15 US US19/021,390 patent/US20250197518A1/en active Pending
- 2025-12-02 JP JP2025219116A patent/JP2026035775A/ja active Pending
-
2026
- 2026-02-19 AU AU2026201242A patent/AU2026201242A1/en active Pending
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