JP2021522242A5 - - Google Patents
Info
- Publication number
- JP2021522242A5 JP2021522242A5 JP2020559394A JP2020559394A JP2021522242A5 JP 2021522242 A5 JP2021522242 A5 JP 2021522242A5 JP 2020559394 A JP2020559394 A JP 2020559394A JP 2020559394 A JP2020559394 A JP 2020559394A JP 2021522242 A5 JP2021522242 A5 JP 2021522242A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound according
- ring
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023092450A JP2023101824A (ja) | 2018-04-24 | 2023-06-05 | 抗増殖性化合物およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862661719P | 2018-04-24 | 2018-04-24 | |
| US62/661,719 | 2018-04-24 | ||
| PCT/US2019/028607 WO2019209759A1 (en) | 2018-04-24 | 2019-04-23 | Antiproliferation compounds and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023092450A Division JP2023101824A (ja) | 2018-04-24 | 2023-06-05 | 抗増殖性化合物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021522242A JP2021522242A (ja) | 2021-08-30 |
| JP2021522242A5 true JP2021522242A5 (https=) | 2022-04-13 |
| JP7304892B2 JP7304892B2 (ja) | 2023-07-07 |
Family
ID=66655429
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020559394A Active JP7304892B2 (ja) | 2018-04-24 | 2019-04-23 | 抗増殖性化合物およびその使用 |
| JP2023092450A Pending JP2023101824A (ja) | 2018-04-24 | 2023-06-05 | 抗増殖性化合物およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023092450A Pending JP2023101824A (ja) | 2018-04-24 | 2023-06-05 | 抗増殖性化合物およびその使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US10815225B2 (https=) |
| EP (2) | EP3784666B1 (https=) |
| JP (2) | JP7304892B2 (https=) |
| KR (1) | KR102813581B1 (https=) |
| CN (1) | CN112236428B (https=) |
| AR (1) | AR114496A1 (https=) |
| AU (1) | AU2019261308B2 (https=) |
| BR (1) | BR112020020940A2 (https=) |
| CA (1) | CA3098335A1 (https=) |
| CY (1) | CY1125433T1 (https=) |
| DK (2) | DK4043460T3 (https=) |
| ES (2) | ES2987356T3 (https=) |
| FI (1) | FI4043460T3 (https=) |
| HR (2) | HRP20241163T1 (https=) |
| HU (2) | HUE058746T2 (https=) |
| IL (2) | IL278142B2 (https=) |
| LT (1) | LT3784666T (https=) |
| MX (1) | MX2020011089A (https=) |
| PL (2) | PL3784666T3 (https=) |
| PT (2) | PT3784666T (https=) |
| RS (1) | RS63281B1 (https=) |
| SG (1) | SG11202009500QA (https=) |
| SI (1) | SI3784666T1 (https=) |
| SM (1) | SMT202200308T1 (https=) |
| TW (1) | TWI813673B (https=) |
| WO (1) | WO2019209759A1 (https=) |
| ZA (1) | ZA202006071B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20241163T1 (hr) | 2018-04-24 | 2024-11-22 | Merck Patent Gmbh | Antiproliferacijski spojevi i njihova uporaba |
| WO2020010451A1 (en) * | 2018-07-10 | 2020-01-16 | Trillium Therapeutics Inc. | Heteroaromatic-fused imidazolyl amides, compositions and uses thereof as sting agonists |
| WO2020236834A1 (en) * | 2019-05-20 | 2020-11-26 | Seshadri Raju | Modified z stents for iliac vein stenting |
| CN118496197A (zh) | 2019-12-20 | 2024-08-16 | 拜耳公司 | 取代的噻吩甲酰胺、噻吩甲酸及其衍生物 |
| WO2024073502A1 (en) * | 2022-09-28 | 2024-04-04 | Accutar Biotechnology Inc. | Heterocyclic compounds as e3 ligase inhibitors |
| TW202547516A (zh) * | 2024-04-26 | 2025-12-16 | 大陸商正大天晴藥業集團股份有限公司 | 稠合雙環化合物及其用途 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| DE19840028A1 (de) | 1998-09-02 | 2000-03-09 | Max Planck Gesellschaft | Nucleinsäuremoleküle codierend Enzyme, die Fructosyltransferaseaktivität besitzen, und deren Verwendung |
| DE60037345T2 (de) | 1999-12-10 | 2008-11-13 | Pfizer Products Inc., Groton | Pyrrolo(2,3-d)pyrimidin-Verbindungen |
| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
| DE60217322T2 (de) | 2001-04-27 | 2007-10-04 | Zenyaku Kogyo K.K. | Heterocyclische verbindung und antitumormittel, das diese als wirkstoff enthält |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| PT1536827E (pt) | 2002-08-14 | 2009-03-20 | Silence Therapeutics Ag | Utilização de proteína cinase n beta |
| AU2004228668B2 (en) | 2003-04-03 | 2011-10-27 | Park Funding, Llc | PI-3 kinase inhibitor prodrugs |
| ES2382377T3 (es) | 2003-05-30 | 2012-06-07 | Gemin X Pharmaceuticals Canada Inc. | Compuestos triheterocíclicos, composiciones, y métodos para tratar cáncer |
| EP1692153A4 (en) | 2003-07-03 | 2007-03-21 | Univ Pennsylvania | INHIBITION OF EXPRESSION OF SYK-KINASE |
| WO2005113556A1 (en) | 2004-05-13 | 2005-12-01 | Icos Corporation | Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta |
| AU2006206458B2 (en) | 2005-01-19 | 2012-10-25 | Rigel Pharmaceuticals, Inc. | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
| PL1888550T3 (pl) | 2005-05-12 | 2014-12-31 | Abbvie Bahamas Ltd | Promotory apoptozy |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| US7402325B2 (en) | 2005-07-28 | 2008-07-22 | Phoenix Biotechnology, Inc. | Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander |
| US7989622B2 (en) | 2005-10-07 | 2011-08-02 | Exelixis, Inc. | Phosphatidylinositol 3-kinase inhibitors and methods of their use |
| JP5191391B2 (ja) | 2005-11-01 | 2013-05-08 | ターゲジェン インコーポレーティッド | キナーゼのビ−アリールメタ−ピリミジン阻害剤 |
| SG10202003901UA (en) | 2005-12-13 | 2020-05-28 | Incyte Holdings Corp | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| WO2007129161A2 (en) | 2006-04-26 | 2007-11-15 | F. Hoffmann-La Roche Ag | Thieno [3, 2-d] pyrimidine derivative useful as pi3k inhibitor |
| DK2526933T3 (en) | 2006-09-22 | 2015-05-18 | Pharmacyclics Inc | Inhibitors of Bruton's tyrosine kinase |
| PE20081229A1 (es) | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
| KR101566840B1 (ko) | 2007-03-12 | 2015-11-06 | 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 | 페닐 아미노 피리미딘 화합물 및 이의 용도 |
| WO2008118802A1 (en) | 2007-03-23 | 2008-10-02 | Regents Of The University Of Minnesota | Therapeutic compounds |
| PE20090717A1 (es) | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| HUE029767T2 (en) | 2008-03-11 | 2017-04-28 | Incyte Holdings Corp | JAK inhibitor azetidine and cyclobutane derivatives |
| US8338439B2 (en) | 2008-06-27 | 2012-12-25 | Celgene Avilomics Research, Inc. | 2,4-disubstituted pyrimidines useful as kinase inhibitors |
| DE102008031517A1 (de) * | 2008-07-03 | 2010-01-07 | Merck Patent Gmbh | Pyrrolopyridinyl-pyrimidin-2-yl-amin-derivate |
| CA2729045A1 (en) | 2008-07-31 | 2010-02-04 | Philippe Bergeron | Pyrimidine compounds, compositions and methods of use |
| AR076014A1 (es) | 2009-04-02 | 2011-05-11 | Sanofi Aventis | Derivados de 3- (1,4) oxazepan -4-pirimidona |
| BR112012012905A2 (pt) * | 2009-12-04 | 2017-03-01 | Hoffmann La Roche | derivados de difenil azepina como inibidores da reabsorção de monoamina |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| EP3256132A1 (en) * | 2015-02-13 | 2017-12-20 | Merck Patent GmbH | Pyrimidine derivatives for use in the treatment of cancer |
| HRP20241163T1 (hr) | 2018-04-24 | 2024-11-22 | Merck Patent Gmbh | Antiproliferacijski spojevi i njihova uporaba |
-
2019
- 2019-04-23 HR HRP20241163TT patent/HRP20241163T1/hr unknown
- 2019-04-23 DK DK22161962.0T patent/DK4043460T3/da active
- 2019-04-23 ES ES22161962T patent/ES2987356T3/es active Active
- 2019-04-23 HR HRP20220710TT patent/HRP20220710T1/hr unknown
- 2019-04-23 BR BR112020020940-6A patent/BR112020020940A2/pt active Search and Examination
- 2019-04-23 KR KR1020207033873A patent/KR102813581B1/ko active Active
- 2019-04-23 SM SM20220308T patent/SMT202200308T1/it unknown
- 2019-04-23 AR ARP190101062A patent/AR114496A1/es unknown
- 2019-04-23 PT PT197267925T patent/PT3784666T/pt unknown
- 2019-04-23 SI SI201930251T patent/SI3784666T1/sl unknown
- 2019-04-23 US US16/391,419 patent/US10815225B2/en active Active
- 2019-04-23 PT PT221619620T patent/PT4043460T/pt unknown
- 2019-04-23 LT LTEPPCT/US2019/028607T patent/LT3784666T/lt unknown
- 2019-04-23 IL IL278142A patent/IL278142B2/en unknown
- 2019-04-23 MX MX2020011089A patent/MX2020011089A/es unknown
- 2019-04-23 WO PCT/US2019/028607 patent/WO2019209759A1/en not_active Ceased
- 2019-04-23 AU AU2019261308A patent/AU2019261308B2/en active Active
- 2019-04-23 JP JP2020559394A patent/JP7304892B2/ja active Active
- 2019-04-23 TW TW108114146A patent/TWI813673B/zh active
- 2019-04-23 IL IL301501A patent/IL301501B2/en unknown
- 2019-04-23 FI FIEP22161962.0T patent/FI4043460T3/fi active
- 2019-04-23 HU HUE19726792A patent/HUE058746T2/hu unknown
- 2019-04-23 CA CA3098335A patent/CA3098335A1/en active Pending
- 2019-04-23 ES ES19726792T patent/ES2919572T3/es active Active
- 2019-04-23 EP EP19726792.5A patent/EP3784666B1/en active Active
- 2019-04-23 SG SG11202009500QA patent/SG11202009500QA/en unknown
- 2019-04-23 PL PL19726792.5T patent/PL3784666T3/pl unknown
- 2019-04-23 CN CN201980036896.XA patent/CN112236428B/zh active Active
- 2019-04-23 EP EP22161962.0A patent/EP4043460B1/en active Active
- 2019-04-23 DK DK19726792.5T patent/DK3784666T3/da active
- 2019-04-23 RS RS20220537A patent/RS63281B1/sr unknown
- 2019-04-23 HU HUE22161962A patent/HUE067936T2/hu unknown
- 2019-04-23 PL PL22161962.0T patent/PL4043460T3/pl unknown
-
2020
- 2020-08-27 US US17/004,109 patent/US11440907B1/en active Active
- 2020-09-30 ZA ZA2020/06071A patent/ZA202006071B/en unknown
-
2022
- 2022-06-10 CY CY20221100409T patent/CY1125433T1/el unknown
- 2022-09-07 US US17/930,352 patent/US12195453B2/en active Active
-
2023
- 2023-06-05 JP JP2023092450A patent/JP2023101824A/ja active Pending
-
2024
- 2024-11-08 US US18/941,447 patent/US20250188070A1/en active Pending
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