JP2021521119A5 - - Google Patents
Info
- Publication number
- JP2021521119A5 JP2021521119A5 JP2020555099A JP2020555099A JP2021521119A5 JP 2021521119 A5 JP2021521119 A5 JP 2021521119A5 JP 2020555099 A JP2020555099 A JP 2020555099A JP 2020555099 A JP2020555099 A JP 2020555099A JP 2021521119 A5 JP2021521119 A5 JP 2021521119A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- buffer
- chromatography
- ultrafiltration
- antibody construct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024056116A JP2024075786A (ja) | 2018-04-12 | 2024-03-29 | 安定なタンパク質組成物を製造する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656687P | 2018-04-12 | 2018-04-12 | |
| US62/656,687 | 2018-04-12 | ||
| PCT/US2019/024683 WO2019199476A1 (en) | 2018-04-12 | 2019-03-28 | Methods for making stable protein compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056116A Division JP2024075786A (ja) | 2018-04-12 | 2024-03-29 | 安定なタンパク質組成物を製造する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021521119A JP2021521119A (ja) | 2021-08-26 |
| JP2021521119A5 true JP2021521119A5 (cg-RX-API-DMAC10.html) | 2022-03-30 |
| JP7465215B2 JP7465215B2 (ja) | 2024-04-10 |
Family
ID=66251859
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555099A Active JP7465215B2 (ja) | 2018-04-12 | 2019-03-28 | 安定なタンパク質組成物を製造する方法 |
| JP2024056116A Pending JP2024075786A (ja) | 2018-04-12 | 2024-03-29 | 安定なタンパク質組成物を製造する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024056116A Pending JP2024075786A (ja) | 2018-04-12 | 2024-03-29 | 安定なタンパク質組成物を製造する方法 |
Country Status (15)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014018747A2 (en) | 2012-07-26 | 2014-01-30 | Momenta Pharmaceuticals, Inc. | Glycoproteins with anti-inflammatory properties |
| ES2708759T3 (es) | 2013-05-13 | 2019-04-11 | Momenta Pharmaceuticals Inc | Procedimientos para el tratamiento de la neurodegeneración |
| EP3058084A4 (en) | 2013-10-16 | 2017-07-05 | Momenta Pharmaceuticals, Inc. | Sialylated glycoproteins |
| RS67656B1 (sr) | 2018-05-10 | 2026-02-27 | Regeneron Pharma | Formulacije koje sadrže visoke koncentracije fuzionog proteina vegf receptora |
| WO2021097344A1 (en) * | 2019-11-13 | 2021-05-20 | Amgen Inc. | Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules |
| CA3194520A1 (en) * | 2020-06-11 | 2021-12-16 | 2Seventy Bio, Inc. | Methods for manufacturing viral vectors |
| US12286451B2 (en) | 2020-11-23 | 2025-04-29 | Medtech Products Inc. | Borate ester complexes of α-hydroxy carboxylic acids and their conjugate base buffers |
| EP4259192A4 (en) * | 2020-12-09 | 2024-11-20 | Dr. Reddy's Laboratories Limited | STABLE AQUEOUS BUFFER-FREE FORMULATION OF AN INTEGRIN ANTIBODY |
| MX2023010372A (es) * | 2021-03-10 | 2023-09-12 | Bausch & Lomb Ireland Ltd | Soluciones oftálmicas. |
| WO2024165043A1 (en) * | 2023-02-08 | 2024-08-15 | Beigene Switzerland Gmbh | Preparation methods for a highly concentrated pd1 antibody solution by applying single-pass tangential flow filtration (sptff) |
| CN117088974B (zh) * | 2023-08-14 | 2024-02-13 | 武汉健昊生物科技有限公司 | 一种抗体保存液 |
| WO2026159667A1 (en) * | 2025-01-24 | 2026-07-30 | Hovione Farmaciência Sa | Synthetic sugars as enablers for viscosity reduction of highly concentrated biological molecules |
| CN121587349B (zh) * | 2026-01-28 | 2026-06-09 | 内蒙古蒙牛乳业（集团）股份有限公司 | 高浓度无菌乳铁蛋白液及其制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| WO2006073417A2 (en) | 2004-05-10 | 2006-07-13 | Curagen Corporation | Prophylactic and therapeutic uses of fgf-20 in radiation protection |
| US20060051347A1 (en) | 2004-09-09 | 2006-03-09 | Winter Charles M | Process for concentration of antibodies and therapeutic products thereof |
| AU2005304973A1 (en) | 2004-11-05 | 2006-05-18 | Palingen, Inc. | Antibody induced cell membrane wounding |
| DK1915398T3 (en) | 2005-07-18 | 2016-07-04 | Amgen Inc | Humane anti-B7RP1 neutraliserende antistoffer |
| US20070190057A1 (en) | 2006-01-23 | 2007-08-16 | Jian Wu | Methods for modulating mannose content of recombinant proteins |
| WO2008119567A2 (en) | 2007-04-03 | 2008-10-09 | Micromet Ag | Cross-species-specific cd3-epsilon binding domain |
| TWI569810B (zh) * | 2007-06-26 | 2017-02-11 | 巴克斯歐塔公司 | 可水解之聚合茀基甲氧基羰基－連接劑 |
| JP5718640B2 (ja) | 2007-08-21 | 2015-05-13 | アムジエン・インコーポレーテツド | ヒトｃ−ｆｍｓ抗原結合性タンパク質 |
| US20130195888A1 (en) * | 2007-11-30 | 2013-08-01 | Abbvie | Ultrafiltration and diafiltration formulation methods for protein processing |
| US8420081B2 (en) * | 2007-11-30 | 2013-04-16 | Abbvie, Inc. | Antibody formulations and methods of making same |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| JO3382B1 (ar) | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
| JP5789521B2 (ja) * | 2009-03-03 | 2015-10-07 | グリフオルス・セラピユーテイクス・インコーポレーテツドＧｒｉｆｏｌｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | プラスミノーゲンを製造するための組成物、方法およびキット；ならびにそれから製造されるプラスミン |
| US20100278822A1 (en) * | 2009-05-04 | 2010-11-04 | Abbott Biotechnology, Ltd. | Stable high protein concentration formulations of human anti-tnf-alpha-antibodies |
| AU2010202125B1 (en) | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
| US8772462B2 (en) | 2010-05-26 | 2014-07-08 | Baxter International Inc. | Removal of serine proteases by treatment with finely divided silicon dioxide |
| PL2616090T3 (pl) | 2010-09-17 | 2023-12-18 | Takeda Pharmaceutical Company Limited | Stabilizowanie immunoglobulin poprzez wodną formulację z histydyną o ph od słabo kwaśnego do obojętnego |
| AU2012250924B2 (en) | 2011-05-02 | 2017-05-25 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
| ES2381828B1 (es) | 2012-03-20 | 2012-11-16 | Grifols, S.A. | PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO |
| US20140154270A1 (en) * | 2012-05-21 | 2014-06-05 | Chen Wang | Purification of non-human antibodies using kosmotropic salt enhanced protein a affinity chromatography |
| WO2014110246A1 (en) | 2013-01-09 | 2014-07-17 | Shire Human Genetic Therapies, Inc. | Methods for purification of arylsulfatase a |
| KR102215405B1 (ko) | 2013-03-15 | 2021-02-10 | 암젠 인크 | 인간 pac1 항체 |
| US20160347833A1 (en) * | 2014-02-07 | 2016-12-01 | Novo Nordisk A/S | Antibody process |
| WO2016009049A1 (en) | 2014-07-18 | 2016-01-21 | Sandoz Ag | Methods for purifying tnfr:fc |
| EP3226896A1 (en) | 2014-12-02 | 2017-10-11 | Biogen MA Inc. | Methods and compositions for controlling antibody aggregation |
| EA039859B1 (ru) | 2015-07-31 | 2022-03-21 | Эмджен Рисерч (Мюник) Гмбх | Биспецифические конструкты антител, связывающие egfrviii и cd3 |
| CA3031860A1 (en) | 2016-08-17 | 2018-02-22 | Boehringer Ingelheim International Gmbh | Process for the preparation of highly concentrated liquid formulations containing biomolecules |
| GB201707484D0 (en) * | 2017-05-10 | 2017-06-21 | Argenx Bvba | Method of preparing ph-dependent antibodies |
| EP3446710A1 (en) * | 2017-08-25 | 2019-02-27 | Glenmark Pharmaceuticals S.A. | Methods of inactivating viral contaminants |
| GB2636539A (en) * | 2023-03-16 | 2025-06-25 | Univ Of Sunderland | Wound dressing |
-
2019
- 2019-03-28 EP EP19719397.2A patent/EP3774894A1/en active Pending
- 2019-03-28 EA EA202092464A patent/EA202092464A1/ru unknown
- 2019-03-28 CA CA3096374A patent/CA3096374A1/en active Pending
- 2019-03-28 WO PCT/US2019/024683 patent/WO2019199476A1/en not_active Ceased
- 2019-03-28 MX MX2020010724A patent/MX2020010724A/es unknown
- 2019-03-28 CN CN201980025383.9A patent/CN111971302A/zh active Pending
- 2019-03-28 SG SG11202010100QA patent/SG11202010100QA/en unknown
- 2019-03-28 MA MA052204A patent/MA52204A/fr unknown
- 2019-03-28 BR BR112020020854-0A patent/BR112020020854A2/pt unknown
- 2019-03-28 KR KR1020207032156A patent/KR102791798B1/ko active Active
- 2019-03-28 US US17/046,662 patent/US12679865B2/en active Active
- 2019-03-28 IL IL277797A patent/IL277797B1/en unknown
- 2019-03-28 JP JP2020555099A patent/JP7465215B2/ja active Active
- 2019-03-28 AU AU2019250882A patent/AU2019250882B2/en active Active
-
2020
- 2020-10-08 CL CL2020002597A patent/CL2020002597A1/es unknown
- 2020-10-09 MX MX2025009986A patent/MX2025009986A/es unknown
-
2024
- 2024-03-29 JP JP2024056116A patent/JP2024075786A/ja active Pending
-
2026
- 2026-01-14 AU AU2026200233A patent/AU2026200233A1/en active Pending
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