JP2021519764A5 - - Google Patents

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Publication number
JP2021519764A5
JP2021519764A5 JP2020552324A JP2020552324A JP2021519764A5 JP 2021519764 A5 JP2021519764 A5 JP 2021519764A5 JP 2020552324 A JP2020552324 A JP 2020552324A JP 2020552324 A JP2020552324 A JP 2020552324A JP 2021519764 A5 JP2021519764 A5 JP 2021519764A5
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JP
Japan
Prior art keywords
optionally substituted
substituted
membered
nhc
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020552324A
Other languages
English (en)
Japanese (ja)
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JP2021519764A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/023917 external-priority patent/WO2019190999A1/en
Publication of JP2021519764A publication Critical patent/JP2021519764A/ja
Publication of JP2021519764A5 publication Critical patent/JP2021519764A5/ja
Pending legal-status Critical Current

Links

JP2020552324A 2018-03-28 2019-03-25 線維性疾患を処置する方法 Pending JP2021519764A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862649428P 2018-03-28 2018-03-28
US62/649,428 2018-03-28
PCT/US2019/023917 WO2019190999A1 (en) 2018-03-28 2019-03-25 Method of treating fibrotic disease

Publications (2)

Publication Number Publication Date
JP2021519764A JP2021519764A (ja) 2021-08-12
JP2021519764A5 true JP2021519764A5 (enExample) 2022-03-31

Family

ID=68060720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020552324A Pending JP2021519764A (ja) 2018-03-28 2019-03-25 線維性疾患を処置する方法

Country Status (15)

Country Link
US (1) US20210113560A1 (enExample)
EP (1) EP3774785A4 (enExample)
JP (1) JP2021519764A (enExample)
KR (1) KR20200139721A (enExample)
CN (1) CN112166111A (enExample)
AU (1) AU2019242595A1 (enExample)
BR (1) BR112020019325A2 (enExample)
CA (1) CA3093749A1 (enExample)
CL (1) CL2020002465A1 (enExample)
IL (1) IL277500A (enExample)
MX (1) MX2020010034A (enExample)
RU (1) RU2020130012A (enExample)
SG (1) SG11202008773PA (enExample)
TW (1) TW202003503A (enExample)
WO (1) WO2019190999A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017292646A1 (en) 2016-07-05 2019-02-07 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
US10934261B2 (en) 2016-09-28 2021-03-02 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
CA3095164A1 (en) * 2018-03-28 2019-10-03 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
EP3820864A4 (en) * 2018-06-28 2022-03-30 Blade Therapeutics, Inc. METHOD OF TREATMENT OF HEPATIC FIBROSIS USING CALPAIN INHIBITORS
BR112022025037A2 (pt) 2020-06-10 2023-02-14 Aligos Therapeutics Inc Compostos antivirais para tratar infecções por coronavírus, picornavírus e norovírus
WO2023283256A1 (en) 2021-07-09 2023-01-12 Aligos Therapeutics, Inc. Anti-viral compounds
US12065428B2 (en) 2021-09-17 2024-08-20 Aligos Therapeutics, Inc. Anti-viral compounds
AU2023303408A1 (en) 2022-07-06 2024-12-19 Aligos Therapeutics, Inc. Anti-viral compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4544993A (en) * 1992-06-24 1994-01-24 Cortex Pharmaceuticals, Inc. Use of calpain inhibitors in the inhibition and treatment of medical conditions associated with increased calpain activity
EP0699074B1 (en) * 1993-04-30 2002-11-13 Merck & Co. Inc. Thrombin inhibitors
AU5526098A (en) * 1996-12-23 1998-07-17 Biochem Pharma Inc. Bicyclic thrombin inhibitors
TR199902692T2 (xx) * 1997-05-02 2000-07-21 Akzo Nobel N.V. Serin proteaz inhibit�rleri.
DE19817459A1 (de) * 1998-04-20 1999-10-21 Basf Ag Neue heterozyklische substituierte Amide, Herstellung und Anwendung
US20100094755A1 (en) * 2008-10-09 2010-04-15 Nelnet Business Solutions, Inc. Providing payment data tokens for online transactions utilizing hosted inline frames
TWI519530B (zh) * 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 羰醯胺化合物及其作為鈣蛋白酶(calpain)抑制劑之用途
MX2013006419A (es) * 2010-12-09 2013-12-16 Abbvie Inc Compuestos carboxamida y su uso como inhibidores de calpaina v.
US9150545B2 (en) * 2012-04-03 2015-10-06 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors V
WO2014085633A1 (en) * 2012-11-30 2014-06-05 Novomedix, Llc Substituted biaryl sulfonamides and the use thereof
RU2020111934A (ru) * 2013-10-08 2020-04-29 Промедиор, Инк. Способы лечения фиброзного рака
US10934261B2 (en) * 2016-09-28 2021-03-02 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
CA3095164A1 (en) * 2018-03-28 2019-10-03 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof

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